Streptomyces phaeolivaceus: F9278_33535
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Entry
F9278_33535 CDS
T07107
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00020
Citrate cycle (TCA cycle)
sphv00630
Glyoxylate and dicarboxylate metabolism
sphv00785
Lipoic acid metabolism
sphv01100
Metabolic pathways
sphv01110
Biosynthesis of secondary metabolites
sphv01120
Microbial metabolism in diverse environments
sphv01200
Carbon metabolism
sphv01210
2-Oxocarboxylic acid metabolism
Module
sphv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sphv_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
F9278_33535
00630 Glyoxylate and dicarboxylate metabolism
F9278_33535
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F9278_33535
Enzymes [BR:
sphv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
F9278_33535
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
F9278_33535
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
F9278_33535
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
F9278_33535
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QFR00282
UniProt:
A0A5P8KB04
LinkDB
All DBs
Position
complement(7223176..7226973)
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AA seq
1265 aa
AA seq
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MSPQSPSNSSISTDADQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASAPASTAAAGAAATTTPAAPAAPAQAAPAAQAAPAPAAPKPAAAPAPAPAKPAAA
APAPAKPVAAAPAKQAAPAAAAAGGPELITLRGPAAAVAKNMNASLELPTATSVRAVPVK
LLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAEKDGKPTLVKPPHV
NFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVS
LTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGIAKVMTLTSTYDH
RVIQGAASGEFLRVVANSLLGENGFYDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARV
FELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSLMKLR
DILGVLRDSYCRTTGVEFMHIQDPKQRRWIQDRIERPHTKPEREEQLRILRRLNAAEAFE
TFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKS
YAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPIVE
GVSRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINN
QVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVID
LICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQG
QLEKVFTEVREATSQPASAEVHDPQDGFPVAVNTAITAETVKRIAESQVNVPDHITAHPR
LLPQLQRRASMVEDGTIDWGMGETLAIGSLLLEGTPVRLAGQDSQRGTFGQRHAVIIDRE
TGEEFTPLMYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNGAQ
TVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSP
SNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGEFRPVIGDGSVDPNAVK
KVVFCAGKVYYDLEAERQKRGVTDTAIIRIERLYPLPGAEVQAEVNKYPNAEKYLWTQEE
PANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLVR
EVFEA
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgcagaccaagcgggtaag
aaccccgccgcggccttcggtccgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagcca
ggcgcagctgccgcctcggctccggcgagcactgcggccgcgggggccgcagcgaccacc
acacccgcggctcccgccgccccggcccaggccgcacccgccgcccaggccgcacccgcc
ccggctgccccgaagcccgccgccgccccggccccggcccccgcgaagcccgcggccgcc
gcgcccgcgccggccaagccggtggccgccgcccccgcgaagcaggccgcgcccgccgct
gccgccgccgggggcccggagctgatcacgctgcgcggccccgccgccgcggtcgcgaag
aacatgaacgcctccctggagctgcccacggccacgtccgtgcgcgcggtcccggtgaag
ctgctgttcgacaaccgcatcgtcatcaacaaccatctgaagcgcgcccggggcgggaag
atctccttcacgcacctgatcggctacgcgatggtgcaggccatcaaggccatgccgtcg
atgaactggcactacgcggagaaggacgggaagcccaccctcgtcaagccgccgcacgtc
aacttcggcctcgccatcgacctggtgaagcccaacggcgaccgccagttggtcgtcgcg
ggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatc
gtccgccgcgcccgtgacggcaagctgacgatggacgacttcaccggtgtcacggtctcc
ctgaccaaccccggcggcctcggcaccgtccactccgtgccccgtctgatgcccggtcag
tcggtcatcatgggcgtcggctccatggactacccggccgagttccagggcaccagccag
gacaccctgaacaagctcggcatcgcgaaggtcatgacgctcacgtcgacctacgaccac
cgggtcatccagggcgccgcctccggcgagttcctccgcgtcgtcgccaactccctcctc
ggggagaacggcttctacgacgagatcttcgaggccctgcgcatcccctacgagccggtc
cgctggctcaaggacatcgacgcgtcgcacgacgacgacgtcaccaaggccgcgcgcgtc
ttcgagctgatccactcctaccgggtccgcggccatgtcatggccgacaccgacccgctg
gagtaccgccagcgcaagcaccccgacctggacatcaccgagcacgggctcaccctgtgg
gacctggagcgcgagttcgcggtcggcggcttcgccggcaagtccctgatgaagctccgg
gacatcctcggcgtcctgcgtgactcgtactgccgtacgaccggcgtcgagttcatgcac
atccaggacccgaagcagcgccgctggatccaggaccgcatcgagcgcccgcacaccaag
ccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaggccttcgag
accttcctgcagacgaagtacgtcggccagaagcgcttcagcctggagggcggcgagtcc
gtcatcccgctgctcgacgcggtcatcgactcggcggcggagtcccgtctcgacgaggtc
gtcatcggcatggcccaccgcggccggctgaacgtgctggcgaacatcgtcggcaagtcg
tacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctcc
ggcgacgtgaagtaccacctgggcgccgagggcacgttcacgggcctggacggcgagcag
atcaaggtcagcctggtcgcgaacccctcgcacctggaggccgtggacccgatcgtcgag
ggtgtctcccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctg
cccgtcgccctgcacggcgacgcggccttcgccggccagggcgtggtggccgagacgctc
aacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaac
caggtcggcttcaccgccgccccggagtcctcgcgctcgtcgatgtacgcgacggacgtg
gcgaggatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggccgtggtc
cgcgtcgcgcggctcgccttcgagttccgtcaggcgttcaacaaggacgtggtgatcgac
ctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcgttcacccagccg
ctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctc
atcggtcgcggcgacatcaccctggaagaggccgagcaggcgctccaggactaccagggc
cagctggagaaggtcttcacggaggtccgtgaggccacctcgcagccggcgtccgccgag
gtccacgacccgcaggacggcttcccggtcgcggtgaacaccgcgatcacggcggagacc
gtcaagcggatcgccgagtcccaggtcaacgtcccggaccacatcaccgcccacccgcgg
ctgctcccgcagctccagcgccgggcgtcgatggtcgaggacggcacgatcgactggggc
atgggcgagaccctcgcgatcggctccctcctccttgagggcaccccggtccgcctggcc
ggccaggactcgcagcgcggcaccttcggccagcggcacgcggtgatcatcgaccgtgag
acgggcgaggagttcacgccgctgatgtacctctccgaggaccaggcgcggctgaacgtc
tacaactccctgctctccgagtacgcggcgatgggcttcgagtacggctactcgctcgcc
cgccccgagtccctggtgatgtgggaggcccagttcggcgacttcgtcaacggcgcccag
acggtcgtggacgagttcatctcgtcggcggagcagaagtggggccagacctccggcgtc
acgctcctcctcccgcacggctacgagggccagggcccggaccactcgtcggcccgcccg
gagcgcttcctccagctctgcgcgcagaacaacatgacggtcgcgatgccgacctcgccg
tcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtc
gtcttcaccccgaagtcgatgctgcgtctcaaggccgccgcgtcgaaggcggaggagttc
acgagcggcgagttccgcccggtcatcggcgacggctcggtcgacccgaacgcggtcaag
aaggtcgtcttctgcgccggcaaggtctactacgacctggaggccgagcgtcagaagcgc
ggcgtcacggacacggcgatcatccgcatcgagcggctgtacccgctgccgggcgccgag
gtccaggccgaggtcaacaagtacccgaacgccgagaagtacctctggacgcaggaggag
ccggcgaaccagggtgcctggccgttcatcgccctcaacctgatcgaccacctcgacctc
gcggtcggcgcggacgtcccccacggcgagcgcctgcgccgtatctcccgcccgcacggc
tcctcgccggcggtgggttcggccaagcgccaccaggccgagcaggagcagttggtgcgt
gaggtgttcgaggcgtaa
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