Streptomyces phaeoluteigriseus: NFX46_06340
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Entry
NFX46_06340 CDS
T08568
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sphw
Streptomyces phaeoluteigriseus
Pathway
sphw00020
Citrate cycle (TCA cycle)
sphw00630
Glyoxylate and dicarboxylate metabolism
sphw00785
Lipoic acid metabolism
sphw01100
Metabolic pathways
sphw01110
Biosynthesis of secondary metabolites
sphw01120
Microbial metabolism in diverse environments
sphw01200
Carbon metabolism
sphw01210
2-Oxocarboxylic acid metabolism
Module
sphw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sphw_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sphw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
NFX46_06340
00630 Glyoxylate and dicarboxylate metabolism
NFX46_06340
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NFX46_06340
Enzymes [BR:
sphw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
NFX46_06340
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
NFX46_06340
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
NFX46_06340
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
NFX46_06340
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
USQ83440
UniProt:
A0ABY4Z3C6
LinkDB
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Position
complement(1375540..1379343)
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AA seq
1267 aa
AA seq
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MSPQSPSNASSISTDADQTGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAAPSAPAGTAAAGAAATTSTPAAPAAPAAPAAAAAPAQAAPAAPAPAPAPVAPTPAA
AAPAPAKAAAPAAKPAAKAEPAASPEGPEYVTLRGPSAAVVKNMNASLELPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKISFTHLIGFAMVQAIKAMPSMNWHYAEKDGKPTLVKPP
HVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVT
VSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTY
DHRVIQGAASGEFLRIVANLLLGEQGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAA
RVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSLMK
LRDILGVLRDSYCRTTGVEFMHIQDPKQRRWIQDRIERSHTKPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAVDPV
LEGIARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVI
NNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVV
IDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDY
QGQLEKVFTEVREATAQPAPGTSPDPQDGFPVAVNTAISAEVVKRIAESQVNIPDHITAH
PRLLPQLQRRATMVEDGTIDWGMGETLAVGSLLLEGVPVRLAGQDSQRGTFGQRHAVIID
RETGEEFTPLMYLADEQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNG
AQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQNNMTVAMPT
LPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDASVDPAA
VKKVVFCAGKVYYDLESERQKRGSTDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQ
EEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQL
VREVFEA
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaacgcatcgagcatctcgaccgacgcagaccaaacgggc
aagaatcccgcggccgcgttcggaccgaacgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaattcggtcgaccgtgcctggtgggacttcttcgccgactacaag
ccgggcgccgccgcgccctcggctccggcgggtactgcggccgcgggggccgcagcgacc
accagcacgcccgcggctcccgccgcacctgcggcgccggccgccgcggccgctccggcc
caggccgcgcccgcagccccggctcccgcaccggcgccggtcgccccgacgcccgcggcg
gccgctccggctcccgccaaggccgcggccccggccgcgaagccggccgccaaggccgag
cccgccgcctctcccgagggccccgagtacgtgacgctgcgcggcccgtccgccgcggtc
gtcaagaacatgaacgcctcgctggaactgcccacggccacgtccgtgcgcgcggtcccg
gtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccggggc
gggaagatctccttcacgcacctgatcggcttcgcgatggtgcaggccatcaaggccatg
ccgtcgatgaactggcactacgcggagaaggacgggaagccaaccctcgtcaagccgccg
cacgtcaacttcggcctggccatcgacctggtgaagcccaacggcgaccgccagctcgtc
gtcgccggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgag
gacatcgtccgccgcgcccgtgacggcaagctgacgatggacgacttcaccggcgtcacc
gtctcgctgaccaaccccggcggcctcggcaccgtccactccgtcccgcgcctgatgccc
ggccagtcggtcatcatgggcgtcggctcgatggactacccggcggagttccagggcacc
agccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctac
gaccaccgggtcatccagggcgccgcctccggcgagttcctgcgcatcgtcgcgaacctc
ctcctcggcgagcagggcttctacgacgacatcttcgaggcgctgcgcatcccctacgag
ccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaaggccgcc
cgcgtcttcgagctgatccactcctaccgggtccgcggccatgtcatggccgacaccgac
ccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggtctgacg
ctctgggacctggagcgcgagttcgccgtcggcggcttcgcgggcaagtccctgatgaag
ctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcgtcgagttc
atgcacatccaggaccccaagcagcgcaggtggatccaggaccgcatcgagcgctcgcac
accaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaggcc
ttcgagaccttcctgcagacgaagtacgtcggccagaagcgcttctccctggagggcggc
gagtccgtcatcccgctgctcgacgcggtgctggactcggccgccgagtcccgcctcgac
gaggtcgtcatcggcatggcccaccgcggccggctgaacgtcctggccaacatcgtcggc
aagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggcctggacggc
gagcagatcaaggtctcgctcgccgcgaacccctcccacctggaggcggtcgacccggtt
ctggagggcatcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcacg
gtcctgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtggtggccgag
accctgaacatgtcgcagctgcggggctaccgcaccggcggcacggtccacatcgtcatc
aacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctccatgtacgcgacg
gacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggcc
gtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttcaacaaggacgtggtg
atcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacc
cagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgag
tccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcgctccaggactac
cagggccagctggagaaggtcttcacggaggtccgcgaggccaccgcgcagcccgccccc
ggcacctcccccgacccgcaggacggcttcccggtcgcggtgaacaccgcgatctcggcg
gaggtcgtcaagcgcatcgccgagtcccaggtcaacatccccgaccacatcaccgcccac
ccgcgcctgctgccgcagctccagcgccgggccacgatggtcgaggacggcacgatcgac
tggggcatgggcgagacgctggccgtcggctccctcctcctggagggcgtcccggtccgc
ctggccggccaggactcccagcgcggtacgttcggacagcggcacgccgtgatcatcgac
cgggagaccggcgaggagttcacgccgctgatgtacctcgcggacgagcaggcgcgcctg
aacgtctacaactccctcctctccgagtacgcggcgatgggcttcgagtacggctactcg
ctggcccgccccgacgcgctcgtgctgtgggaggcccagttcggcgacttcgtcaacggc
gcccagacggtcgtggacgagttcatctcgtcggcggagcagaagtggggccagacgtcc
ggcgtcaccctgctcctcccgcacggctacgagggccagggcccggaccactcgtccgcc
cgcccggagcgcttcctccagatgtgcgcccagaacaacatgacggtcgccatgccgacc
ctgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccg
ctggtcgtcttcaccccgaagtcgatgctgcgcctcaaggccgcggcgtcgaaggcggag
gagttcacgacgggccagttccgcccggtcatcggcgacgcctcggtcgacccggccgcc
gtcaagaaggtcgtcttctgcgccggcaaggtctactacgacctggagtccgagcgtcag
aagcgcggctccacggacacggcgatcatccgcatcgagcgcctgtacccgctgccgggt
gccgagctccaggcggagatcgccaagtacccgaacgccgagaagtacctgtgggcccag
gaggagccggcgaaccagggtgcctggccgttcatcgccctgaacctgatcgaccacctg
gacctggccgtcggcgcggacgtgccgcacggcgagcgcctgcgccgcatctcgcggccg
cacggctcgtccccggcggtcggctcggccaagcgtcaccaggccgagcaggagcagttg
gtgcgtgaggtgttcgaggcgtag
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