KEGG   Streptomyces phaeoluteigriseus: NFX46_07355
Entry
NFX46_07355       CDS       T08568                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
sphw  Streptomyces phaeoluteigriseus
Pathway
sphw03030  DNA replication
sphw03410  Base excision repair
sphw03420  Nucleotide excision repair
sphw03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:sphw00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    NFX46_07355 (ligA)
   03410 Base excision repair
    NFX46_07355 (ligA)
   03420 Nucleotide excision repair
    NFX46_07355 (ligA)
   03430 Mismatch repair
    NFX46_07355 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:sphw03032]
    NFX46_07355 (ligA)
   03400 DNA repair and recombination proteins [BR:sphw03400]
    NFX46_07355 (ligA)
Enzymes [BR:sphw01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     NFX46_07355 (ligA)
DNA replication proteins [BR:sphw03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     NFX46_07355 (ligA)
DNA repair and recombination proteins [BR:sphw03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     NFX46_07355 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     NFX46_07355 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     NFX46_07355 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      NFX46_07355 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_5 HHH NHase_beta_N
Other DBs
NCBI-ProteinID: USQ83622
LinkDB
Position
1606045..1608240
AA seq 731 aa
MAGDRQAETTVPSEAREKHAQLAEQIEEHRFRYYVKDAPVVSDAEFDRLLRSLEALEEQY
PELRTPDSPTQKVAGAYETEFTAVQHRERMLSLDNAFDDLELAAWAERVHKDVGASAYHF
LCELKVDGLAVNLTYENGRLTRAATRGDGRTGEDITPNVRTIAEIPDRLTGHGVPSLVEI
RGEVYFPMEKFEELNARLVEAGDKPFANPRNAAAGSLRQKDPRVTANRPLHMVVHGIGAL
EGYEGLTRLSEAYDLLKSWGLPTSRHNKVVDDLDGVRAFIAYYGENRHSVEHEIDGVVVK
LDEIRLQGRLGSTARAPRWAIAYKYAPEEVNTKLLNIRVGVGRTGRVTPYAQVEPVTVAG
SEVEFATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGSEREFVMPSECPE
CDTPLRPMKEGDVDLRCPNARACPAQLRERLFYLAGRKALDIDHFGYVSAAALTKPLEPE
QPPLTDEGDLFDLTIEQLLPIKAYVLDQNSGLPKRDPKTGEEKIVTVFANQQGEPKKNAL
AMLDTIAAAKERPLVRILTGLSIRHVGPVAAEALAREFRSIDRIEQASEEELAGTDGVGP
IIAASLKEWFAEDWHREIIRKWKAAGVRMEEEGSGEDEGPRPLEGLTVVVTGTLEHFTRD
GAKDALQSRGAKVTGSVSKKTSFVVVGDSPGSKYDKAMQLKVPVLDEDGFTVLLEQGAEA
AAEVALPVPES
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtggccggcgacaggcaagcggagacgacggtgccctcggaggcgcgggagaagcacgcg
cagctcgctgagcagatcgaggagcaccgcttccggtactacgtgaaggacgcccccgtc
gtcagtgacgcggagttcgaccgcctcctgcgctccctggaggcgctggaggagcagtac
cccgagctgcgcaccccggactcgccgacccagaaggtagcgggggcgtacgagacggag
ttcaccgccgtccagcaccgcgagcgcatgctgtcgctggacaacgccttcgacgatctg
gagctggccgcctgggcagagcgcgtccacaaggacgtcggcgcctccgcgtaccacttc
ctgtgcgagctgaaggtcgacggactcgccgtcaacctgacgtacgagaacggccggctg
acccgcgcggccacccgcggcgacggccggaccggcgaggacatcacgcccaacgtgcgg
accatcgcggagatcccggaccggctgaccggacacggcgtcccgtccctcgtcgagatc
cgcggcgaggtctacttcccgatggagaagttcgaggagctgaacgcccgtctggtcgag
gccggcgacaagcccttcgccaatccgcgcaacgcggccgccggttcgctgcgccagaag
gacccgcgcgtcaccgccaaccgccccctgcacatggtggtccacggcatcggcgccctg
gaggggtacgagggcctcacccgcctctccgaggcgtacgacctcctcaagtcctggggc
ctgcccacctcccggcacaacaaggtggtcgacgacctcgacggcgtacgggcgttcatc
gcgtactacggcgagaaccggcactccgtggagcacgagatcgacggtgtcgtcgtcaag
ctcgacgagatccggctccaggggcggctcggctccacggcccgcgcgccgcgctgggcg
atcgcgtacaagtacgcgccggaggaggtcaacaccaagctcctcaacatccgcgtgggc
gtgggccgcaccggccgcgtcaccccgtacgcccaggtcgagccggtgaccgtggccggt
tccgaggtcgagttcgcgaccctgcacaaccaggacgtcgtcaaggccaagggcgtcctc
atcggcgacaccgtggtgctgcgcaaggccggtgacgtcatcccggagatcctcggtccg
gtcgccgacctgcgggacggcagcgagcgcgagttcgtcatgccgtcggagtgccccgag
tgcgacaccccgctgcggccgatgaaggagggcgacgtcgacctgcgctgccccaacgcc
cgtgcctgcccggcccagttgcgcgagcgcctcttctacctcgccggccgcaaggccctg
gacatcgaccacttcgggtacgtctccgccgcggccctgaccaagccgctggagcccgag
cagccgccgctgaccgacgagggcgacctgttcgacctcaccatcgagcaactgctgccc
atcaaggcgtacgtcctcgaccagaacagcggactgcccaagcgggacccgaagaccggc
gaggagaagatcgtcaccgtcttcgccaaccagcagggcgagccgaagaagaacgcgctc
gccatgctggacaccatcgcggcagccaaggagcgcccgctggtccgcatcctcaccggc
ctgtccatccggcacgtggggccggtcgcggccgaggcgctggcccgcgagttccgctcc
atcgaccgcatcgaacaggcgagcgaggaggagctggccgggaccgacggggtcggcccg
atcatcgcggcctccctcaaggagtggttcgccgaggactggcaccgcgagatcatccgc
aagtggaaggccgccggcgtccgcatggaggaggagggctccggcgaggacgagggcccg
cgcccgctggaaggcctcaccgtcgtggtcaccggcaccctggagcacttcacccgggac
ggcgccaaggacgccctccagagccgcggggcgaaggtgaccggatcggtctcgaagaag
acctcgttcgtcgttgtgggtgacagccccggatcgaagtacgacaaggccatgcagctg
aaggttccggtgctggacgaggacggcttcacggtcctcctcgaacaaggggcggaggcg
gccgccgaagtcgccctgccggtccccgagtcgtga

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