Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0032
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Entry
MGAS10750_Spy0032 CDS
T00356
Symbol
purK
Name
(GenBank) Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit
KO
K01589
5-(carboxyamino)imidazole ribonucleotide synthase [EC:
6.3.4.18
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00230
Purine metabolism
spi01100
Metabolic pathways
spi01110
Biosynthesis of secondary metabolites
Module
spi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10750_Spy0032 (purK)
Enzymes [BR:
spi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase
MGAS10750_Spy0032 (purK)
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Ortholog
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GFIT
Motif
Pfam:
ATP-grasp
RS_preATP-grasp-like
PurK_C
Dala_Dala_lig_C
ATP-grasp_3
2-Hacid_dh_C
CPSase_L_D2
SPO1_gp41
Rossmann-like
NAD_binding_2
3HCDH_N
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
ABF36982
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Position
49069..50202
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AA seq
377 aa
AA seq
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MRNKEKSQRSQVVNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDCPASRVSEVI
VAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNRIVEKDF
LANKAGVTVAPYKVMTSSLDLGGLDLTKTYVLKTATGGYDGHGQKIIRSAEDLPEAQQLA
NSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPARISDQLADKA
KKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEACDFSQFDTHILGV
LGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVTENPSAHLHMYGKLEAKHNRKMGHVTVLK
EDEVEFGEEINWKYGEI
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgaggaacaaggaaaaatcgcagaggagtcaagtggtgaactcatttaagaccattggg
attattggtggtggtcagctggggcagatgatggcgattgcggctatctacatgggccac
aaggtcatcacgctggatcctgctagcgactgccctgcctcccgcgttagcgaggtaatt
gtggcgccttacgatgatgttgaggctttgggacaattggctgcgcgttgcgatgtattg
acttatgagtttgagaatgttgatgcggacggtttggatgccgttgtgtcagcttgtcag
ctaccgcaggggaccgatctgctccgcatttcccaaaaccgtatcgttgaaaaagacttt
ctggcaaataaggctggtgtgacagtcgctccctataaggtgatgacgtctagccttgac
ctaggggggcttgatttgaccaagacctatgtcctcaagacagcgacaggtggttatgac
ggtcatgggcaaaagattatccgctcagcagaagatttgccagaggcgcagcaattagct
aactcagctcagtgtgtcttggaagagtttgtcaatttcgaccttgaaatctcagttatc
gtgtctggaaacggagaggatgtgacggtctttcccgttcaggaaaatatccactgcaat
aatatcctgtcaaaaactatcgtgccagctcgcatctcagatcaactggctgataaggct
aagaaaatggcggtgcagattgccaagaaactccagctgtcaggaactctctgtgtggaa
atgtttgcgaccgcagatgatatcattgtcaatgaaattgccccacgtccccacaactca
gggcactactcaatcgaggcttgcgacttttcacagtttgacacccacattttgggcgtg
ctaggagcgccgctcccaaccatccacctccatgctccagccgtcatgcttaatgtcctc
ggacaacacgtccagcaggcaattgactatgtgactgaaaaccctagcgcccacctccac
atgtatggtaaactagaagcgaaacataaccgcaaaatgggacacgtgacggtgttgaaa
gaagatgaagtagagtttggggaagagattaattggaagtatggagaaatttaa
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