Sardina pilchardus (sardine): 134078497
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Entry
134078497 CDS
T10667
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
spil Sardina pilchardus (sardine)
Pathway
spil00140
Steroid hormone biosynthesis
spil01100
Metabolic pathways
Module
spil_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
spil_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
spil_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
spil00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
134078497 (hsd3b1)
Enzymes [BR:
spil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
134078497 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
134078497 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
NAD_binding_10
Polysacc_synt_2
KR
NmrA
RmlD_sub_bind
adh_short
DUF5849
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
134078497
NCBI-ProteinID:
XP_062390453
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Position
4:19985786..19989544
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AA seq
374 aa
AA seq
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MSLSGDVCVVTGACGFLGQHLVKLLLEEEKLAEIRLLDRSVQPELIQDLEGKRGETTVSV
FEGDIRDADLLRRACRGASIVFHTVSLIDVIGALKYSELHGVNVKGTQMLLEACVQENVC
SLIYTSSIEVAGPNPRGDPVVNGDEDTPYSACLRFPYSRTKKEAEDLCLRAQGEVLRNGG
RLATCALRPMYIYGAGCRFTLGHMRDGIRNGHVLLRASPRRALVNPVYVGNVAAAHLQAA
RALRDPRTRAAVGGNVYYVADDTPPVSYSDFNHAVLAPLGFGIQERPALPFPVLYVVCFL
MEMLQTVLRPFVQFAPPLNRQLLTMLYTPFSFSYQKAKRDLGYTPRYSWEEARKTTTDWL
ALMLAKERAQVKAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtcgttgtcaggagacgtgtgtgtggtgacgggagcttgcggattcctggggcagcac
ctggtgaagctactcctggaggaggagaagctggctgagatccgactgctggacaggagc
gtccaaccggaactcatacaggacctggaaggtaaaaggggtgagacgacagtgagcgtg
tttgagggagacatcagggacgctgatctcctgaggagagcctgtcggggcgcatccatc
gttttccacacggtctccctcatcgacgtcataggagcactgaagtacagtgaactccac
ggggtcaatgtcaaagggacccagatgcttctggaagcgtgcgtccaggagaacgtctgc
tcgctcatctacacgagcagcatcgaggtggccggccccaacccccgcggcgaccccgtg
gtcaacggcgacgaggacacgccgtactccgcctgcctgaggttcccctacagccgcacc
aagaaggaggccgaggacctgtgcctccgcgcccagggcgaggtgctccgcaacgggggc
cgcctggccacctgcgccctgcggcccatgtacatctacggcgccggctgccgcttcacg
ctgggccacatgcgcgacggcatccgcaacggccacgtgctcctgcgggcgtcgccgcgc
cgcgcgctcgtcaaccccgtctacgtgggcaacgtggccgccgcgcacctccaggccgcc
cgggcgctccgcgacccgcgcacgagggcggcggtcggcgggaacgtgtactacgtggcg
gacgacacgccgccggtcagctactcggacttcaaccacgccgtgctggcgccgctggga
ttcgggatccaggagcggccggcgctcccgttccccgtgctctacgtcgtctgcttcctg
atggagatgctgcagacggtcctccgccccttcgtgcagttcgctccgcccctgaacagg
cagctgctgaccatgctgtacacgcccttctcgttctcctaccagaaggccaagagggat
ttggggtacacaccccgatatagttgggaggaggcgcgcaagaccaccactgattggctg
gccttaatgctggccaaggagagagcccaagtcaaagccaaatga
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