KEGG   Sardina pilchardus (sardine): 134101865
Entry
134101865         CDS       T10667                                 
Symbol
map2k2a
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2a
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
spil  Sardina pilchardus (sardine)
Pathway
spil04010  MAPK signaling pathway
spil04012  ErbB signaling pathway
spil04068  FoxO signaling pathway
spil04140  Autophagy - animal
spil04148  Efferocytosis
spil04150  mTOR signaling pathway
spil04210  Apoptosis
spil04218  Cellular senescence
spil04270  Vascular smooth muscle contraction
spil04370  VEGF signaling pathway
spil04371  Apelin signaling pathway
spil04517  IgSF CAM signaling
spil04519  Cadherin signaling
spil04540  Gap junction
spil04620  Toll-like receptor signaling pathway
spil04810  Regulation of actin cytoskeleton
spil04910  Insulin signaling pathway
spil04912  GnRH signaling pathway
spil04916  Melanogenesis
spil05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:spil00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    134101865 (map2k2a)
   04012 ErbB signaling pathway
    134101865 (map2k2a)
   04370 VEGF signaling pathway
    134101865 (map2k2a)
   04371 Apelin signaling pathway
    134101865 (map2k2a)
   04068 FoxO signaling pathway
    134101865 (map2k2a)
   04150 mTOR signaling pathway
    134101865 (map2k2a)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    134101865 (map2k2a)
   04519 Cadherin signaling
    134101865 (map2k2a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    134101865 (map2k2a)
   04148 Efferocytosis
    134101865 (map2k2a)
  09143 Cell growth and death
   04210 Apoptosis
    134101865 (map2k2a)
   04218 Cellular senescence
    134101865 (map2k2a)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    134101865 (map2k2a)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    134101865 (map2k2a)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    134101865 (map2k2a)
  09152 Endocrine system
   04910 Insulin signaling pathway
    134101865 (map2k2a)
   04912 GnRH signaling pathway
    134101865 (map2k2a)
   04916 Melanogenesis
    134101865 (map2k2a)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    134101865 (map2k2a)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    134101865 (map2k2a)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:spil01001]
    134101865 (map2k2a)
Enzymes [BR:spil01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     134101865 (map2k2a)
Protein kinases [BR:spil01001]
 Serine/threonine kinases: STE group
  STE7 family
   134101865 (map2k2a)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 APH
Other DBs
NCBI-GeneID: 134101865
NCBI-ProteinID: XP_062411699
LinkDB
Position
15:23161530..23170380
AA seq 397 aa
MAPKKRPGPIVITPAGEGQAVSTNAAIEASLVDLPKMLGELDLDEQQRKRLEAFLTQKAK
VGELKDDDFHLICELGAGNGGVVHKVRHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLH
ECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRVPEEILGKVSIAVLRGLAY
LREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH
YSVQSDVWSMGLSLVELAIGRFPIPPPDARELEAIFGRCVLNEAGGEQLSTSPRPKPPGR
PVSGHGMDSRPAMAIFELLDYIVNEPPPKLPHGVYTSDFQDFVNKCLIKNPADRADLKML
VSHTFIKRAEVEKVDFAGWLCKTMGLNQPSTPTRCAE
NT seq 1194 nt   +upstreamnt  +downstreamnt
atggccccaaagaagagacctggccccattgtcataacacctgctggagaggggcaagcg
gtttcaaccaatgcagcaattgaggccagtctagttgacctaccgaaaatgttaggggaa
ctggacttggatgagcagcagaggaaacgcttggaggctttcctcacccagaaagcaaag
gtgggcgaactcaaagatgatgacttccacctcatctgtgagctcggtgccggcaacggt
ggagtggtccacaaagtccgtcacaaaccctctggactagtcatggcaaggaagcttatc
catttagaaatcaagccagcgatcaggaaccagatcatcagagagcttcaagtgctgcac
gagtgcaactcgccctacatagtgggcttctatggggctttctacagcgacggcgagatc
agcatctgtatggagcatatggatggagggtcccttgaccaggtgctgaaagaagccaag
agagtcccagaagaaatacttgggaaagtcagcatagctgtacttagaggactggcgtac
ctccgagagaagcatcaaattatgcatagagacgtcaaaccgtccaacatcttggtgaac
tcgcgaggggagatcaagctgtgcgactttggcgtgagcggccagctcatcgactccatg
gccaactccttcgtgggaacccgttcctacatgtcgccggagagactgcagggcacgcac
tactcggtgcagtcggacgtgtggagcatgggcctgtccctggtggagctggccatcggc
cgcttccccatccccccgcccgacgcccgggagctggaggccatcttcgggcgctgcgtg
ctcaacgaggccggcggggagcagctcagcacctcgccgaggcccaagccccctggacgg
cctgtcagcggacacggaatggacagtcgtccggcgatggctatatttgaactactggac
tacattgtcaatgagcctccgcccaagctgccacatggagtctacacctccgacttccag
gactttgtgaacaaatgcctcataaagaaccctgcggaccgggccgacctgaagatgctg
gtgagtcacaccttcatcaagcgcgccgaggtagagaaggtggacttcgccggctggctg
tgcaaaaccatgggcctcaaccaacccagcactccgacccgatgtgccgaatga

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