Streptomyces platensis: CP981_10810
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Entry
CP981_10810 CDS
T07341
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
spla
Streptomyces platensis
Pathway
spla00010
Glycolysis / Gluconeogenesis
spla00020
Citrate cycle (TCA cycle)
spla00620
Pyruvate metabolism
spla00785
Lipoic acid metabolism
spla01100
Metabolic pathways
spla01110
Biosynthesis of secondary metabolites
spla01120
Microbial metabolism in diverse environments
spla01200
Carbon metabolism
spla01210
2-Oxocarboxylic acid metabolism
Module
spla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP981_10810 (aceE)
00020 Citrate cycle (TCA cycle)
CP981_10810 (aceE)
00620 Pyruvate metabolism
CP981_10810 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP981_10810 (aceE)
Enzymes [BR:
spla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP981_10810 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
AAA_lid_2
Motif
Other DBs
NCBI-ProteinID:
QEV52089
UniProt:
A0AAE6NFM8
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All DBs
Position
2496474..2499146
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AA seq
890 aa
AA seq
DB search
MPDPVRLPYSQLDQLPDRDPEETSEWRESLDAVTKAAGPHRAAYLMRRALEHTARTEGTA
LPSLLETDYVNTIPTSAEPAFPGDEAMEARITAWNRWNAAAMVTRGSALGLGGHIATFAS
AAWLYETGFQHFFRGKEGDGSGDQLYIQGHASPGVYARAFLEGRLTEDHLDRFRQETGGE
GLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRGIKDTANSHVWAFLGDGE
MDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRPNFKIVQELEAQFRAAGWNVVKS
LWGRAWDEIFALDTDGALIRRLGETPDAQFQTYATRDAAYLREHFFGANESLRALAAGLS
DAKLLELFQTSRAGHEPRKVYAAYKAAVEHQGAPTVILAQTVKGYTLGAGFESRNANHQM
KKLTMAEFRTMRDVLELPIPDSALEGDQVPYWRPAEDSPEMVYLRERRTALDGPAPARKV
VAKPLPMPADKAFDALKKGSGSQEIATTMAFVRLIKDLMRDKETGKRWVPIVPDEARTFG
MESLFPTAGLYSPKGATYDPVDRDQLLWYKEAKNGQILNEGITEAGSLADFTAAATSYAT
HGEPMIPFYIFYSMFGWQRTADQFWALADQLGRGFVIGATAGRTTMTGEGLQHADGHSHL
IASTNPAALSYDPAFAYEVAVIVKEGLRRMYGPEAEDVFYYLTVYNETKVQPAMPEGVEE
GILKGLYRFNEGTRPEADSPQLQLLASGTAIHWALEAQQLLAADWGVAADVWSAPSWTEL
RRDALECDAARLDGDDRIPYVTRALAGAPGPVIAVSDWMRAVPDQIAPWVEQDWTSIGTD
GFGLSDTREAARRHFGVDPQSVVVQALAALARRGEVKPEAVKEAKERYGL
NT seq
2673 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcccgtgcgcctgccgtacagccagctcgaccagctcccggatcgcgacccc
gaggagacgagcgagtggcgcgagtcgctcgacgccgtcaccaaggcagccggcccgcat
cgcgccgcgtacctcatgcgccgtgcccttgagcacaccgcgcgcaccgagggcaccgcc
ctgccgtccctcctggagacggactacgtcaacaccatcccgacctccgccgagcccgcc
ttcccgggcgacgaggcgatggaggccaggatcaccgcctggaaccgctggaacgccgcc
gcgatggtcacccgcggctccgcgctgggcctcggcggccacatcgccaccttcgcctcc
gccgcctggctctacgagaccggcttccagcacttcttccgcggcaaggaaggcgacggc
agcggcgaccagctctacatccagggccacgcctcccccggcgtctacgcccgcgccttc
ctcgaaggccgcctcaccgaggaccacctcgaccgcttccgccaggagaccggcggcgag
ggcctgccctcctacccgcacccgcggcggctgccctggctgtgggagttccccaccgtc
tccatgggactcggcccgctctccgcgatctaccaggcgcgcttcaaccgctacctggag
caccgcggcatcaaggacaccgccaactcccacgtctgggccttcctgggcgacggcgag
atggacgagcccgagtcgaccgccgccctggcgttggccggccgcgagggcctggacaac
ctgaccttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgccccaacttc
aagatcgtgcaggagctggaggcccagttccgcgcggccggctggaacgtcgtcaagtcg
ctgtggggccgcgcctgggacgagatcttcgccctcgacaccgacggcgccctgatccgc
cgcctcggcgagacccccgacgcgcagttccagacgtacgccacccgcgacgccgcctac
ctgcgcgaacacttcttcggcgccaacgagtccctccgggcgctcgccgccggcctgtcc
gacgccaagctgctggagctgttccagacctcccgggccggccacgagccgcgcaaggtg
tacgccgcctacaaggccgccgtcgagcaccagggcgcgcccaccgtcatcctggcgcag
accgtcaagggctacaccctcggcgcgggcttcgagtcccgcaacgccaaccaccagatg
aagaagctcaccatggcggagttccgcaccatgcgtgacgtgctcgaactccccatcccg
gacagcgcgctggaaggcgaccaggtgccgtactggcgccccgccgaggactcccccgag
atggtctacctgcgcgagcggcgcaccgccctcgacggcccggcccccgcccgcaaggtc
gtcgccaagccgctgccgatgcccgccgacaaggccttcgacgccctgaagaagggctcc
ggcagccaggagatcgccaccaccatggcgttcgtccggctgatcaaggacctgatgcgg
gacaaggagaccggcaagcgctgggtccccatcgtccccgacgaggcccgcaccttcggt
atggagtccctcttcccgacggccggcctctactcccccaagggcgcgacgtacgacccg
gtcgaccgcgatcagctgctctggtacaaggaagccaagaacggccagatcctcaacgag
ggcatcaccgaggccggttcgctcgccgacttcaccgccgccgcgacctcgtacgcgacg
cacggcgagccgatgatccccttctacatcttctactcgatgttcggctggcagcgcacc
gccgaccagttctgggcactggccgaccagttgggccgcggcttcgtcatcggcgccacc
gccggccgcaccacgatgaccggcgagggcctccagcacgccgacggccactcgcacctg
atcgcctccaccaacccggcggcgctctcctacgacccggccttcgcctacgaggtcgcg
gtcatcgtcaaggagggcctgcgccggatgtacggccccgaggccgaggacgtcttctac
tacctcacggtctacaacgagaccaaggtccagccggccatgccggagggcgtcgaagag
ggcatcctcaagggcctgtaccgcttcaacgagggcacccgtcccgaggccgacagcccg
cagctccagctgctggcatccggcaccgccatccactgggccctggaggcacagcagctg
ctggccgccgactggggtgtggcggcggacgtctggtcggccccgtcctggacggagctg
cgccgggacgccctggagtgcgatgccgcccgtctggacggcgacgaccgcatcccgtac
gtcacccgcgccctggccggcgcccccggcccggtcatcgcggtcagcgactggatgcgc
gccgtccccgaccagatcgccccctgggtcgagcaggactggacctccatcggcaccgac
ggcttcggcctctccgacacccgcgaggcggcccgccgccacttcggtgtcgacccccag
tcggtcgtcgtccaggccctggccgcactcgcccgccgcggcgaggtcaagccggaggcc
gtcaaggaggccaaggagcggtacggcctgtaa
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