KEGG   Streptomyces platensis: CP981_12390
Entry
CP981_12390       CDS       T07341                                 
Name
(GenBank) peptidase M15D vanX D-ala-D-ala dipeptidase
  KO
K08641  zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
Organism
spla  Streptomyces platensis
Pathway
spla01502  Vancomycin resistance
spla02020  Two-component system
Brite
KEGG Orthology (KO) [BR:spla00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    CP981_12390
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    CP981_12390
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:spla01002]
    CP981_12390
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:spla01011]
    CP981_12390
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:spla01504]
    CP981_12390
Enzymes [BR:spla01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.13  Dipeptidases
    3.4.13.22  D-Ala-D-Ala dipeptidase
     CP981_12390
Peptidases and inhibitors [BR:spla01002]
 Metallo peptidases
  Family M15: zinc D-Ala-D-Ala carboxypeptidase family
   CP981_12390
Peptidoglycan biosynthesis and degradation proteins [BR:spla01011]
 Peptidoglycan biosynthesis and degradation
  Carboxypeptidase
   CP981_12390
Antimicrobial resistance genes [BR:spla01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
    CP981_12390
SSDB
Motif
Pfam: CN_hydrolase Peptidase_M15 VanY DUF1265 Rv0078B
Other DBs
NCBI-ProteinID: QEV52359
UniProt: A0AAE6NG63
LinkDB
Position
2832278..2833672
AA seq 464 aa
MIIAAAQFLPVPGDIEANAARMAGLLTEAAGRGAGLVVFPELALTHYDLALIAADPVGMT
VTADDARLAPVREACRATGTAAVVNAAGRATGGGSRPAISSFVIGPDGALVTRYDKVHLF
GDENTVFAPGSAPGRCTLGGIRFALATCFDNSHPEVAARAAADGCRVSLASSFHGSAERV
AGYAQQARDHGLQVLLANGMGTGGSASGCGLSGAWLPSGERVAAAAEWTGPVPGDGAELV
FTDVRDRITLMADPAVAAVPVEECGEPLVDVRAAEPALLVAEDRNDPLGAYAFLREGMLQ
RLLAAQKSLPDGLRLQFVEGYRPPGLQRRYFEEYADELRAAHPDWDAARLHQAASRYVSP
PEIAPHSAGGAVDLTLVTTEGEPVDMGTPINASPEESDGACYTAAPELTPVARAHRRVLN
AALTAAGLVNYPTEWWHWSYGDRYWALATGADHALYGPTEPAGR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgatcattgctgccgcacaattcctcccggtaccgggcgatatcgaggccaatgccgcc
cggatggccgggcttctcaccgaggccgccgggcgcggcgcggggctggtggtcttcccc
gaactcgcgctgacgcactacgacctggccctgatagccgccgacccggtgggcatgacg
gtcacggcggacgacgcccggctggcacccgtacgggaggcctgccgggcgaccgggacc
gcggcggtcgtgaacgcggcgggccgtgccaccggcggcgggtcccgtccggccatctcc
tcgttcgtcatcggcccggacggcgccctggtcacccgctacgacaaggtccatctgttc
ggggacgagaacaccgtgttcgcgccggggagcgcgccgggccgctgcaccctgggcggc
atccggttcgcgctcgccacctgcttcgacaacagccaccccgaggtggcggcgcgggcc
gcggcggacggctgccgggtgtcgctcgccagctccttccacggctcggcggagcgcgtg
gcgggatatgcgcagcaggcgcgggaccacggtctgcaggtgctgctcgccaacggcatg
gggaccggcggctccgcttcggggtgcggtctcagtggcgcctggctgccgtcgggtgag
cgggtggcggcggccgccgagtggaccgggccggtgccgggggacggtgcggagctggtg
ttcaccgatgtccgtgaccggatcacgctgatggcggacccggcggtggccgcggtcccc
gtcgaggagtgcggtgagccgctggtggacgtacgtgccgcggagcccgcgctgctcgtg
gccgaggaccggaacgacccgctcggcgcctatgccttcctgcgggaaggcatgctccaa
cggctgctggcggcgcagaagtcactgccggacgggctgcggttgcagttcgtcgagggc
taccggccgccgggactccagcgccgctacttcgaggagtacgcggacgagctgcgcgcc
gcccaccccgactgggacgccgcccggctccaccaggccgccagccgctatgtgtcgccg
cccgagatcgcaccgcacagcgccggtggcgcggtggacctcaccctcgtcaccaccgag
ggggaacccgtcgacatggggacgccgatcaatgcctcccccgaggagagcgacggcgcc
tgctacacggccgcgccggagctgacacccgtcgcccgcgcccaccgccgggtgctgaac
gccgcgctgaccgccgccgggctggtcaactacccgaccgagtggtggcactggtcctac
ggcgaccgctactgggcgctggcgaccggcgcggaccacgcgctgtacgggccgacggag
ccggccgggcggtga

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