Streptomyces pluripotens: LK06_007795
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Entry
LK06_007795 CDS
T04845
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00010
Glycolysis / Gluconeogenesis
splu00020
Citrate cycle (TCA cycle)
splu00620
Pyruvate metabolism
splu00785
Lipoic acid metabolism
splu01100
Metabolic pathways
splu01110
Biosynthesis of secondary metabolites
splu01120
Microbial metabolism in diverse environments
splu01200
Carbon metabolism
splu01210
2-Oxocarboxylic acid metabolism
Module
splu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LK06_007795
00020 Citrate cycle (TCA cycle)
LK06_007795
00620 Pyruvate metabolism
LK06_007795
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LK06_007795
Enzymes [BR:
splu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LK06_007795
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ARP69877
UniProt:
A0A221NX77
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Position
1766450..1769161
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AA seq
903 aa
AA seq
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MTDPHAIQPSELDQLPDRDPEETAEWQASLDAVAREAGPHRAAYLMRRTLERAEAGGIAL
PKLLETDYVNTIPTSAEPAVPGDPEMEARITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFNHFFKGKESPDAAGSGDQLYIQGHASPGIYARAFLDGRLTEQHLDNFRQEAG
GNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSASHVWAFLGD
GEMDEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVV
KTLWGSAWDELFQLDTTGALVRRLRDVPDAQIQTYQTRDAAYIRQDFFGADPALAQMAKL
LSDDKIIECFHLSRGGHEVRKVHAAYRAAVEHKGAPTVILAQTVKGHTLGEGFASKNANH
QMKKLTVDEFTTMRDLLDLPIKDSDFADGTVPYGHPGADSPEVRYLQERRAALGGPAPAR
RVHPVAPLPAPAERAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGRRWVPIVPDEAR
TFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTS
YATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLIGATAGRTTLTGEGLQHADGH
SPVIAATNPAALTYDPAFAYEIAVIVREGLRRMYGEAKPGEDQNVFYYLTVYNEPLPQPA
KPQGLGVDEGIVKGLYRFNTAESAGVSPVANAPRIQLLGSGTAIHWALEAQQLLAEEWGV
AADVWSATSWSELRRDAMDADAALLRGEERVPYIRQALQGAEGPVLAVSDYMRQTPDQIA
QWVEQDYSSLGADGFGLSDTREAARRHFGVDARSIVVAALAQLAKRGEVKAAAVKEAREK
YGL
NT seq
2712 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccccacgccatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatggcaggcctccctggacgccgtggccagggaggccgggccgcac
cgcgccgcatacctgatgcgccgcacgctggagcgcgccgaggcgggcggcatcgcgctg
ccgaagctcctcgaaacggactacgtcaacaccatccccacctccgccgagccggccgtt
cccggcgacccggagatggaggcccggatcaccgcctggaaccgctggaacgcggccgcg
atggtgacccgcggctccaagcacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagtccccggatgcc
gccggctccggcgaccagctgtacatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccgactgaccgaacagcacctggacaacttccgtcaggaggccggc
ggcaacggcctgccgtcctatccgcacccgcggcgcctgccctggctgtgggagttcccc
accgtctccatgggcctcggcccgctgtcggcgatctaccaggcccggttcaaccgctac
ctgaccaaccgcggcatcaaggacgtctccgcctcccacgtctgggccttcctcggcgac
ggcgagatggacgagccggagtcgacggcggccctcgcgctcgccgcccgggagcagttg
gacaacctcaccttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgcc
aacttcaagatcgtgcaggagctggaggcccagttccgcggtgccggctggaacgtcgtc
aagaccctgtggggctccgcctgggacgagctcttccagctcgacaccaccggcgcactg
gtacgccggctgcgcgacgtaccggacgcacagatccagacgtaccagacccgcgacgcg
gcttacatccgccaggacttcttcggcgccgatccggcgctcgcccagatggcgaagctg
ctgagcgacgacaagatcatcgagtgcttccacctctcgcgtggcggccacgaagtccgc
aaggtccacgccgcgtaccgggccgccgtcgagcacaagggcgcgccgaccgtgatcctg
gcccagacggtcaagggccacaccctcggtgagggcttcgcgtcgaagaacgccaaccac
cagatgaagaagctgacggtggacgagttcacgaccatgcgcgacctgctcgacctgccg
atcaaggacagcgacttcgccgacggcacggtcccctacggccacccgggcgccgactcc
cccgaggtccgctacctccaggaacgccgcgcggccctcggcggcccggccccggcccgt
cgtgtccacccggtggccccgctccccgcccccgctgagagggccttcgcctccttcgac
aagggctccggctcccagaacgtggccaccaccatggccttcgtccgcctggtcaaggac
ctggtccgggacaaggagaccggcaggcgctgggtgccgatcgtcccggacgaggcacgc
accttcggcatggagtccctgttcccgtcgctcgggatctactcccccaagggccagacg
tacgaaccggtcgaccgcgaccagttgatgtactacaaggaggccaagaacggccagatc
ctcaacgaggggatcaccgaggccggttccatggccgacttcatcgccgcttcgacgtcg
tacgcgacgcacggcgaggcgatgatccccttctacatcttctactcgatgttcggctgg
caacgcacggccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctgatc
ggcgccacggccggccgtacgaccctgaccggcgaaggcctgcagcacgccgacggccac
tcccccgtcatcgcggccaccaacccggccgccctcacctacgaccccgccttcgcctac
gagatcgcggtgatcgtccgtgagggcctgcgccggatgtacggcgaggccaaaccgggc
gaggaccagaacgtcttctactacctcaccgtctacaacgagccgctgccgcagcccgcg
aagccgcagggtctcggcgtcgacgagggcatcgtcaagggcctctaccggttcaacacg
gcggagtcggcgggcgtgtccccggtcgccaacgccccgcgcatccagttgctgggctcc
ggcacggcgatccactgggcgctggaggcacagcaactgctggccgaggagtggggtgtg
gccgccgacgtgtggtccgctacctcctggtccgagctgcgccgggacgccatggacgcc
gacgcggccctgttgcgcggcgaggagcgggtgccgtacatccggcaggcgctgcaaggt
gccgagggtccggtcctcgcggtctccgactacatgcgccagacgccggaccagatcgca
cagtgggtcgagcaggactactcctcgctgggcgccgacggcttcggcctttcggacacg
cgtgaagctgcccgccgccacttcggcgtggacgcccggtcgatcgtcgtggcggccctg
gcccagctcgccaagcgcggcgaggtgaaggctgcggcggtgaaggaggcccgggagaag
tacgggctgtag
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