Streptomyces pluripotens: LK06_008780
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Entry
LK06_008780 CDS
T04845
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00010
Glycolysis / Gluconeogenesis
splu00020
Citrate cycle (TCA cycle)
splu00620
Pyruvate metabolism
splu00785
Lipoic acid metabolism
splu01100
Metabolic pathways
splu01110
Biosynthesis of secondary metabolites
splu01120
Microbial metabolism in diverse environments
splu01200
Carbon metabolism
splu01210
2-Oxocarboxylic acid metabolism
Module
splu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LK06_008780
00020 Citrate cycle (TCA cycle)
LK06_008780
00620 Pyruvate metabolism
LK06_008780
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LK06_008780
Enzymes [BR:
splu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LK06_008780
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
ARP70044
UniProt:
A0A221NWC5
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Position
1982210..1984957
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERARER
RVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERRILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDDGRGGDQVFFQGHASPGIYARAYLLDRLAEDQLDGFRQ
EKSKHPNGLSSYPHPRSMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEPESLGQLTLAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGVLVNKMNTTPDGQFQTYATETGAYIRQHFFGDDHRLR
AMVENMTDHQILMLGRGGHDHRKIYAAYKAAVEHKGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPISDKELESGPPPYYHPGRDTEEIQYMHDRRKQCGGYVP
TRIVRAKPLALPDDKTYATVKKGSGQQAIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAYAYEIAHIVQDGLRRMYGGSPEHPYGEDVFYYLTVYNEPIQH
PAEPADVDVEGIVRGIHKIGEGAGGAIPAQIMASGVAVPWALEAQRILAAEWNVRAGVWS
ATSWNELRREAVECEEHNLLHPEEEQRVPFVTRKLRGAEGPFVAVSDWMRSVPDQIARWV
PGPYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELAREGKVDRSALKQAIDRYQL
LDVSAAHPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaatccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaggaaactcaggagtggctcgactccctcgacgccgccgtcgacgag
cgaggccgggaacgggcccgctacctcatgctgcgcctgatcgagcgggcacgcgagcgg
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatccccaccaagagc
gagcccttcttcccgggcaacgaggagatcgagcgccggatcctcaatgcaacccgctgg
aacgcggccgtgatggtctccagagcccagcgcccgggtatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctcgctctacgacgtgggcttcaaccacttcttccggggc
aaggacgacggccgcggcggcgaccaggtcttcttccaaggccacgcctcccccggtatc
tacgcacgcgcatacctgctcgaccggctcgccgaggaccagctggacggtttccgccag
gagaagtcgaaacaccccaacggcctgtccagctatccgcacccgcgctcgatgccggac
ttctgggagttcccgacggtctccatgggcctcggcccgctcggcgccatctaccaggca
cggatgaaccgctacatggaggcgcgtggcatcgccgacacctcccggtcacacgtgtgg
gcgttcctcggcgacggcgagatggacgagccggagtcactcggccagctcacgctggcc
gcccgggagggcttggacaacctgaccttcgtggtcaactgcaacctgcagcggctcgac
ggcccggtacgcggtaacggcaagatcatccaggaactggagtcggtcttccggggcgcc
ggctggaacgtgatcaagctgatctgggaccgctcctgggacccgctgctcgcccaggac
cgggacggtgtgctggtcaacaagatgaacacgaccccggacggccagttccagacgtac
gccaccgagaccggcgcgtacatccgccagcacttcttcggcgacgaccaccggctgcgc
gcgatggtcgagaacatgaccgaccaccagatcctgatgctgggccgcggcggtcacgac
caccgcaagatctacgccgcttacaaggccgccgtcgagcacaagggccagccgacggtg
atcctggccaagacggtcaagggttggacgctgggccccaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctgaagcgcttccgggaccgcctgcac
ctgccgatctcggacaaggagctggagtccggcccgccgccgtactaccacccgggccgg
gacacggaagagatccagtacatgcacgaccggcgcaagcagtgcggtgggtacgtgccg
acccggatcgtgcgcgccaagccgctcgccctacccgacgacaagacgtacgcgaccgtg
aagaagggctccggtcagcaggcgatcgccacaaccatggcgttcgtgcgactgctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtactgatcgcgccggacgaatac
cgcaccttcggcatggactccttcttcccgagcgcgaagatctacaacccgctaggccag
cagtacgaggcggtcgaccgggacctgctcctggcctacaaggagtctcccaccggtcag
atgctgcacgacgggatctccgaggccggctgcacggcctccctgatcgcggcgggctcg
gcgtacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatggccgaccaactggcgcgcggattcgta
ctgggtgcgaccgccggacgcacgacgctgaccggtgagggcctgcaacacgcagacggt
cactcgcagctgctcgcttccaccaacccggcgtgcgtggcgtacgacccggcgtacgcg
tatgagatcgcgcacatcgtgcaggacggtctgcgccgcatgtacggcggctcacccgaa
cacccctacggcgaggacgtcttctactacctcacggtctacaacgagcccatccagcac
cccgccgaaccggcggacgtggacgtggagggcatcgtcaggggcatccacaagatcggg
gagggcgcaggcggcgcgatcccggcacagatcatggcgtcgggtgtggcggtcccgtgg
gctctggaggcccagcggatcctcgcggcggagtggaacgtcagggccggcgtgtggtcc
gcgacctcctggaacgagctgcgcagggaggcggtggagtgcgaggagcacaatctgctg
cacccagaggaggagcagcgggtgccgttcgtgacgcggaaactccgcggtgccgagggc
ccgttcgtcgccgtgtccgactggatgcgatcggttccggaccagatcgcacggtgggtg
ccgggtccgtaccagtcgctcggcgcggacgggttcgggttcgcggacacccggggtgcg
gcgcgccggttcttccacatcgacgcccagtcgatcgtggtggcagtgctgaccgagctg
gcacgcgagggcaaggtggaccgctccgcgctgaagcaggcgatcgaccgttaccagctg
ctggacgtctcggcagcccatcctggtgcggcgggcggcgacgcatga
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