Schizosaccharomyces pombe (fission yeast): 2543141
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Entry
2543141 CDS
T00076
Symbol
hcs1, SPOM_SPAC4F8.14C
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA synthase
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
spo
Schizosaccharomyces pombe (fission yeast)
Pathway
spo00280
Valine, leucine and isoleucine degradation
spo00650
Butanoate metabolism
spo00900
Terpenoid backbone biosynthesis
spo01100
Metabolic pathways
spo01110
Biosynthesis of secondary metabolites
Module
spo_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
spo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
2543141 (hcs1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
2543141 (hcs1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
2543141 (hcs1)
Enzymes [BR:
spo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
2543141 (hcs1)
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Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
Motif
Other DBs
NCBI-GeneID:
2543141
NCBI-ProteinID:
NP_001342835
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Position
I:join(2643624..2643683,2643860..2645143)
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AA seq
447 aa
AA seq
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MSFDRKDIGIKGLVLYTPNQYVEQAALEAHDGVSTGKYTIGLGLTKMAFVDDREDIYSFG
LTALSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKSVLMQLFGDNHNVEGIDCVNACYG
GVNALFNTIDWIESSAWDGRDGIVVAGDIALYAKGNARPTGGAGCVALLVGPNAPIVFEP
GLRGTYMQHAYDFYKPDLTSEYPYVDGHFSLECYVKALDGAYANYNVRDVAKNGKSQGLG
LDRFDYCIFHAPTCKQVQKAYARLLYTDSAAEPSNPELEGVRELLSTLDAKKSLTDKALE
KGLMAITKERFNKRVSPSVYAPTNCGNMYTASIFSCLTALLSRVPADELKGKRVGAYSYG
SGLAASFFSFVVKGDVSEIAKKTNLVNDLDNRHCLTPTQYEEAIELRHQAHLKKNFTPKG
SIERLRSGTYYLTGIDDMFRRSYSVKP
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atgtcctttgatagaaaagatattggtattaagggcctcgtgttgtacactcccaatcag
tatgttgaacaagctgccctcgaagcgcatgatggagtctctactggaaagtatactatt
ggcctcggcttgactaagatggcttttgtcgacgatcgtgaagacatttattcctttggt
cttaccgctctttctcaacttatcaagagataccaaattgatataagcaagattggtcgt
ttggaagttggaactgagactatcatcgataaatctaagtctgtcaaaagtgttttaatg
caactttttggggataaccacaatgtcgaaggtattgattgtgttaatgcctgttatggt
ggcgtgaacgctctttttaacacaatcgattggattgagtcttctgcttgggatggccgt
gatggtatagttgtcgctggtgatattgctctctatgccaagggcaatgctcgtcctacc
ggtggtgctggttgtgtcgcccttttggttggtcctaatgcccctattgtttttgaacct
ggtctacgtggtacttacatgcaacatgcttacgatttttacaaacccgatttgacgagt
gaatacccttacgttgatggccatttttctcttgaatgttatgttaaagctcttgatgga
gcatatgctaattacaatgttcgtgatgttgctaagaatggaaaaagtcaaggacttgga
ttggatcgttttgattattgcattttccacgctcctacttgcaaacaagtccaaaaagca
tatgcgcgtttattgtacaccgatagcgctgctgaaccatctaatcccgagttggaaggt
gtccgtgaacttcttagcaccctggatgctaagaaatcccttaccgacaaggctttagaa
aaaggtcttatggccataactaaagagcgttttaacaaacgagtttcccctagtgtctat
gcccctaccaactgtggtaatatgtacactgccagtattttctcttgtttaactgcatta
cttagccgtgtccccgctgatgaacttaaaggaaaacgcgtcggtgcttactcttatggt
tctggtttggctgcctcgtttttttcattcgttgtcaaaggcgacgtctctgaaattgcc
aagaaaactaacttggttaacgatttggataatcgtcattgtttaacccctacgcagtat
gaagaggctattgagctacgccatcaagcacacttgaaaaagaattttactcccaaagga
agcatcgaacgtcttcgttcaggtacttactaccttactggtattgatgacatgttccgc
cgtagctattcggtgaagccttaa
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