Streptomyces poriferorum: P8A21_27190
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Entry
P8A21_27190 CDS
T10937
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
spof Streptomyces poriferorum
Pathway
spof00020
Citrate cycle (TCA cycle)
spof00630
Glyoxylate and dicarboxylate metabolism
spof00785
Lipoic acid metabolism
spof01100
Metabolic pathways
spof01110
Biosynthesis of secondary metabolites
spof01120
Microbial metabolism in diverse environments
spof01200
Carbon metabolism
spof01210
2-Oxocarboxylic acid metabolism
Module
spof_M00009
Citrate cycle (TCA cycle, Krebs cycle)
spof_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
spof00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
P8A21_27190
00630 Glyoxylate and dicarboxylate metabolism
P8A21_27190
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
P8A21_27190
Enzymes [BR:
spof01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
P8A21_27190
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
P8A21_27190
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
P8A21_27190
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
P8A21_27190
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Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WLQ50940
LinkDB
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Position
complement(6167210..6171022)
Genome browser
AA seq
1270 aa
AA seq
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MSSQSPSNSSISTDQASPGTNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GTSGTADKPVPGAAAAGVAVPAAPAATAPAPAAPAAPAAKAPAVPAAPAPAPAASAPAAP
AAPVKAAPAKAAPAPAAKAPAAPATEAPAGPEYVTLRGPSAAVAKNMNASLELPTATSVR
AVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPAMNYSFAQKDGKPTLV
KPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARNGKLGMDDFT
GVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTLT
STYDHRVIQGAASGEFLRILSQLLLGENEFYDEIFKALRIPYEPVRWLKDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLERDFAVGGFAGKT
MMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRPKPEREEQLRILRRLNA
AEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLNVLAN
IVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAV
DPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVH
VVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQAFNK
DVVIDLICYRRRGHNEGDNPQFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEAEQAL
QDFQGQLEKVFAEVREATSHPAQPHVSDPQAEFPVAVTTAISQEVVKRIAESQVNIPDHI
TVHPRLMPQMQRRAASVEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDTRRGTFGQRHAV
LVDQVTGEDYTPLLYLTDEQARYNVYDSLLSEYAAMGFEYGYSLARPESLVVWEAQFGDF
VNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVA
MPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTVGGFRPVIGDDSVD
PSAVRKVVFCAGKVYYDLDAERQKRGDTETAIIRLERLYPLPGAELQAEIAKYPNAAKYL
WAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPRGSSPAVGSAKRHQAEQ
AQLVAEVFEA
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctccaccgaccaagccagcccgggtacg
aacccggctgccgcttttggccccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggatcccaattcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggtacgtccggcacggcggacaagcccgttcccggcgccgcagccgcgggggttgcggtg
cccgctgcgccggccgccaccgcaccggctccggccgcgccagccgcacccgcggccaag
gctccggccgtacccgctgctccggcgcccgctccggccgcatccgcacctgccgccccg
gcggctccggtgaaggccgcaccggcgaaggccgcaccggctccggccgcgaaggctccc
gccgccccggccaccgaggccccggccggtccggagtacgtgacgctgcgcggcccctcc
gccgctgtcgcgaagaacatgaacgcctcgctggaactgccgacggccacgtccgtccgc
gccgtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgc
gcccgcggcgggaagatctccttcacgcacctcatcgggtacgcgatggtgcaggccctc
aaggccatgccggcgatgaactactccttcgcccagaaggacggcaagccgaccctggtg
aagccggagcacgtcaacctcggcctcgccatcgacctggtgaagccgaacggcgaccgc
cagctggtcgtcgcggccatcaagaaggccgagacgctcaacttcttcgagttctggcag
gcctacgaggacatcgtccgccgggcccgcaacggcaagctcggcatggacgacttcacc
ggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgttcactcggtgccccgc
ctgatgcccggacagggcctcatcatgggcgtcggcgcgatggactaccccgcggagttc
cagggcacgtcgcaggacaccctgaacaagctgggcatctccaaggtcatgacgctgacc
tcgacgtacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcggatcctc
tcccagctgctgctcggcgagaacgagttctacgacgagatcttcaaggcgctgcgcatc
ccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcacc
aaggccgcacgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggcc
gacaccgacccgctggagtaccaccagcgcaagcaccccgacctggacatcaccgagcac
ggcctcaccctgtgggacctggagcgggacttcgcggtcggcggtttcgccggcaagacg
atgatgaagctccgcgacatcctcggtgtgctgcgtgagtcgtactgccgcaccaccggc
atcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggaccgggtggag
cgtccgcgccccaagcccgagcgcgaggagcagctgcgcatcctgcgccggctgaacgcc
gcggaggcgttcgagaccttcctgcagacgaagtacgtcggccagaagcggttctcgctg
gagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgccgccgaggcc
cgcctcgacgaggtcgtcatcggcatggcccaccgcggccggctgaacgtgctggcgaac
atcgtcggcaagtcgtacgcgcagatcttccgggagttcgagggcaacctcgacccgaag
tcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggt
ctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcacctggaggcggtc
gacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaacaagggcggcacg
gacttcaccgtcctgcccgtcgcgctccacggcgacgcggccttcgcgggccagggcgtc
gtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcac
gtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgctcctcgatg
tacgccaccgacgtggcgcgcatgatcgaggcgccgatcatccacgtcaacggtgacgac
cccgaggccgtcgtccgtgtcgcacggctggccttcgagttccgtcaggcgttcaacaag
gacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccg
cagttcaccaacccgcagatgtacaccctgatcgacaagaagcgctcggtgcgcaagctg
tacaccgagtccctcatcggtcgtggcgacatcacgctggaagaggcggagcaggcgctc
caggacttccagggccagctggagaaggtgttcgcggaggtccgcgaggccacctcgcac
ccggcgcagccgcatgtgtcggacccccaggccgagttcccggtggccgtgaccaccgcg
atctcccaggaggtcgtgaagcggatcgccgagtcgcaggtcaacatcccggaccacatc
accgtccacccgcgcctgatgccgcagatgcagcgtcgtgcggcctcggtggaggacggc
acgatcgactggggcatgggcgagaccctggccatcggttcgctgctgatggagggcacc
ccggtccggctcgccggccaggacacccgccgcggcacgttcggccagcgccacgcggtg
ctggtcgaccaggtgaccggcgaggactacaccccgctgctctacctcaccgacgagcag
gcccgttacaacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtac
ggctactcgctggcccgcccggagtcgctcgtcgtctgggaggcccagttcggtgacttc
gtcaacggcgcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggc
cagacctccggcgtcacgctgctgctgccgcacggctacgagggccagggcccggaccac
tcgtccgcccgcccggagcgcttcctccagatgtgcgcgcaggacaacatgacggtcgcg
atgccgaccctgccgtcgaactacttccaccttctgcggtggcaggtgcacaacccgcac
cacaagccgctgatcgtcttcaccccgaagtcgatgctccgcctcaaggcggcggcgtcg
aaggcggaggagttcaccgtcggcggtttccgcccggtgatcggcgacgactcggtcgac
ccgagcgcggtccgcaaggtcgtcttctgcgccggcaaggtctactacgacctggacgcc
gagcgccagaagcgcggcgacacggagaccgcgatcatccgtctggagcgcctgtacccg
ctgccgggcgcggagctccaggccgagatcgccaagtacccgaacgcggcgaagtacctg
tgggcccaggaggagccggccaaccagggcgcatggccgttcatcgccctgaacctgatc
gaccacctggacctggccgtcggcgccgacgtcccgcacggtgagcgcctgcgccgcatc
tcgcggccgcgcggctcttccccggcggtcggctcggccaagcgccaccaggcggagcag
gctcagctggtcgcggaggtcttcgaggcctga
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