KEGG   Streptococcus pneumoniae R6 (avirulent serotype 2): spr1429
Entry
spr1429           CDS       T00060                                 
Symbol
dfr
Name
(GenBank) Dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
spr  Streptococcus pneumoniae R6 (avirulent serotype 2)
Pathway
spr00670  One carbon pool by folate
spr00790  Folate biosynthesis
spr01100  Metabolic pathways
spr01240  Biosynthesis of cofactors
spr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:spr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    spr1429 (dfr)
   00670 One carbon pool by folate
    spr1429 (dfr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    spr1429 (dfr)
Enzymes [BR:spr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     spr1429 (dfr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAL00233
UniProt: Q7CRB0
LinkDB
Position
complement(1412861..1413367)
AA seq 168 aa
MTKKIVAIWAQDEEGLIGKENRLPWHLPAELQHFKETTLNHAILMGRVTFDGMGRRLLPK
RETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGGKQIFQAFEPYLDEVIVTH
IHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTIQYRKRKEV
NT seq 507 nt   +upstreamnt  +downstreamnt
atgactaagaaaatcgtagctatttgggcccaggatgaagagggtttgattggtaaggaa
aatcgtctgccttggcatttgccagcagaattgcagcactttaaagaaacaactctgaat
catgctatcttgatggggcgtgtgacctttgatgggatggggcgtcgcttgcttccaaaa
cgggaaaccctgattttgacgcgtaatccggaagaaaagatagatggggttgctactttt
caggacgtccagtctgttcttgactggtatcaggatcaagaaaagaatctctacattatc
ggtgggaagcaaatttttcaggcttttgaaccttaccttgatgaagtgattgtcactcac
attcatgctcgggtggaaggagatacctatttccctgaagagcttgacttgtctcttttt
gagacagtttcaagcaaattttacgccaaagatgagaagaatccttatgattttaccatc
caataccgcaagagaaaggaagtctaa

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