| Entry |
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| Symbol |
metH
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| Name |
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
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| KO |
| K00548 | 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] |
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| Organism |
spt Salmonella enterica subsp. enterica serovar Paratyphi A ATCC9150
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| Pathway |
| spt00270 | Cysteine and methionine metabolism |
| spt01110 | Biosynthesis of secondary metabolites |
| spt04981 | Folate transport and metabolism |
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| Module |
| spt_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
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| Brite |
KEGG Orthology (KO) [BR:spt00001]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SPA4026 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SPA4026 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPA4026 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SPA4026 (metH)
04980 Cobalamin transport and metabolism
SPA4026 (metH)
Enzymes [BR:spt01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SPA4026 (metH)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
4180422..4184105
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| AA seq |
1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGVDLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGHTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRERKIKICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILKTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGLTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD |
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| NT seq |
3684 nt +upstreamnt +downstreamnt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtactcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaattaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccactaaagcgctggtggaaggtggcgtagatctgattctgatt
gagaccgtctttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgatctgccgatcatgatttccggcaccatcaccgacgcctctggc
catacgctttccggccagacgaccgaagccttttataactcgctgcgccacgccgaagcg
ctcacttttggccttaactgcgcgctggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaa
gcgggcttcctgaatatcgttggcggctgctgtggcactacgccggagcatatcgccgcc
atgagccgcgccgttgccggtttgccgccgcgccagctgccggatatcccggtcgcctgc
cgcctttccggcctggagccgctgaacattggcgacgatagcctgtttgtcaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaagcgcctgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtagaaagcggcgcgcagattattgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggacattgcccgtgtaccaatcatgattgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcctttattcatcatgcgaagttgctacgtcgctatggcgccgcagtg
gtggtcatggcttttgatgagcaggggcaggccgatacccgcgagcgtaaaatcaaaatt
tgccgccgagcctacaaaattttgaccgaagaggtgggtttcccgccggaagatatcatc
ttcgacccgaatatcttcgccgtggcgaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcttgcgaagatattaaacgcgagttgccgcacgcgctgatctccggc
ggtgtgtctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgtcaacgccgga
cagctggctatctacgacgacctgcctgccgaactgcgcgatgcagttgaagatgtcatt
cttaaccgtcgcgatgacggcaccgagcgtttgctggaactggccgagaaataccgcggc
agcaaaaccgacgaagctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgagtttatcgaacaggataccgaa
gaagcccgccagcaggccgcccgcccgattgaggtgattgaagggccgctgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgcccgcgtgatgaaacaagcggtggcctacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtcatcgccaccgtgaagggcgatgtgcacgac
attggcaagaacatcgttggcgtggtgctgcaatgcaacaactacgaaatcgtcgatctt
ggcgtgatggtgcctgcggagaaaatcctcaaaacggcgaaagaggtgaacgcggacctg
atcggcctctccggcctgattacgccgtcgctggatgaaatggtcaacgtggcaaaagag
atggagcgtcagggccttaccatcccactgcttattggcggcgcgacaacgtcgaaagcg
cacacggcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacaaccagcgcgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgt
acgccgccggtcacgctggaagcggcgcgcgataatgatctggcgttcgattgggaacgc
tacaccccgccggtagcccaccgtctgggcgtgcaggaggtggaagccagcatcgaaact
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggc
ctgttcccggcgaaccgtgtgggtgacgacatcgaaatttatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagtcggttttgccaac
tactgtctggcggattttgtcgcgccgaaactgagcggcaaagcggattacatcggtgct
ttcgcggtgaccggcggtctggaggaggatgcgctggcggacgccttcgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgtttgcc
gagtatctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgaggacgttgagcggtggctggcgccg
aacctgggttacgatgcggactga |
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