KEGG   Streptococcus pyogenes M1 GAS (serotype M1): SPy_0883
Entry
SPy_0883          CDS       T00050                                 
Symbol
dyr
Name
(GenBank) putative dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
spy  Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy00670  One carbon pool by folate
spy00790  Folate biosynthesis
spy01100  Metabolic pathways
spy01240  Biosynthesis of cofactors
spy04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:spy00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SPy_0883 (dyr)
   00670 One carbon pool by folate
    SPy_0883 (dyr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    SPy_0883 (dyr)
Enzymes [BR:spy01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SPy_0883 (dyr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAK33803
UniProt: Q9A091
LinkDB
Position
731153..731650
AA seq 165 aa
MTKEIIAIWAEDEAGLIGIAGKLPWYLPKELEHFKKTTLHQAILMGRVTFEGMNCKRLPQ
RQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNKVLEAFNGYFDRIIKTV
IHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALKHK
NT seq 498 nt   +upstreamnt  +downstreamnt
atgacaaaggaaattattgctatttgggcagaggatgaagcagggcttattggtattgcg
ggtaagttaccatggtatttaccaaaagagttagaacattttaaaaagacaacgctacat
caagcaatcttaatgggccgtgtgacttttgaaggaatgaattgcaaaagacttcctcaa
cgtcaaacccttgtcatgacaagaaatagagattatcaagtagatgaggtgttgacaatg
actagtattgaaaaagtcttggagtggtaccatgcgcaggataaaacactttatatcatt
ggtgggaataaggttttagaagcgtttaatggttatttcgatcgtatcataaaaacagtt
atccatcatcgttttaaaggagatacctaccgaccaaatctagattttagtcatttcacg
caagaaagccaaacgttctatgctcgagacgctaaaaatccttatgattttaccgttact
gctttaaaacacaaatag

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