KEGG   Serratia quinivorans: E4343_18335
Entry
E4343_18335       CDS       T05941                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
squ  Serratia quinivorans
Pathway
squ00270  Cysteine and methionine metabolism
squ00450  Selenocompound metabolism
squ00670  One carbon pool by folate
squ01100  Metabolic pathways
squ01110  Biosynthesis of secondary metabolites
squ01230  Biosynthesis of amino acids
squ04981  Folate transport and metabolism
Module
squ_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:squ00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    E4343_18335 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    E4343_18335 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    E4343_18335 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    E4343_18335 (metH)
   04980 Cobalamin transport and metabolism
    E4343_18335 (metH)
Enzymes [BR:squ01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     E4343_18335 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: QBX68012
LinkDB
Position
3901065..3904745
AA seq 1226 aa
MTNRVEQLRRQLAQRILVLDGGMGTMIQSYRLEESDFRGERFADWQSDLKGNNDLLVLTK
PEVITAIHYGYLEAGADILETNTFNSTSIAMADYHMESLSAEINYQAACLARACADEWTA
RTPEQPRYVAGVLGPTNRTASISPNVNDPAFRNVSFDELVEAYRESTRALVEGGVDLIMI
ETIFDTLNAKAAAFAVETEFEALGVALPIMISGTITDASGRTLSGQTTEAFYNSMRHVKP
LSFGLNCALGPDELRQYVSELSRISESYVTAHPNAGLPNAFGEYDLDAQEMAKQVGEWAN
AGFLNIIGGCCGTTPEHIAAMVKAVAGVPPRQLPAIPVACRLAGLEPLNIDAKTLFVNVG
ERTNVTGSARFKRLIKEEKYSEALAVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHAKLVRRYGAAV
VVMAFDEAGQADTRERKFEICRRAYKILTERVGFPPEDIIFDPNIFAVATGIDEHNNYAV
DFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMDMGIVNAG
QLAIYDDLSAELRDAVEDVILNRRDDGTERLLELAEKYRGSKDNEVAVQQAEWRGWPVEK
RLEYSLVKGITEFIELDTEEARQRADRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKS
ARVMKQAVAYLEPYIEASKEKGTTAGKILLATVKGDVHDIGKNIVGVVLQCNNYEIVDLG
VMVPTEKILKTAREQNVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKAH
TAVKIEQNYSGSTTYVQNASRTVGVVSALLSATQRDDFVARTRKEYETVRIQHARKKPRT
PPVSLQKARDNAMVLDWESYQPPVPKRLGVYPVEAGIETLRHYIDWTPFFMTWSLAGKYP
RILEDEVVGEEAKRLFADANQMLDWLAANGSLNPRGVYGLFPANRVGDDVEVYRDENRDE
VLVVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDDLAAAYDAQHD
DYNKIMVKALSDRLAEAFAEYLHEQVRKLHWGFAAEENLSNEELIRENYQGIRPAPGYPA
CPEHTEKAEIWRLLDVNRHTGMVLTESFAMWPGAAVSGWYFSHPQSKYFAVAQLQRDQVE
DYAARKGMSVSEVERWLAPNLGYDAD
NT seq 3681 nt   +upstreamnt  +downstreamnt
gtgacaaatcgagtagaacaactgcgccggcagttagcgcagcgaattttagtgttggat
ggcggcatgggcaccatgatccagagctatcgtctggaagagagtgactttcgtggcgag
cgttttgccgactggcagagcgatctgaaaggcaataatgacctgctggtgctaaccaaa
ccggaagtgatcaccgccattcactacggctacctggaagcgggggccgacattctcgaa
accaataccttcaactccacgtccatcgccatggccgactaccatatggagtcgctgtcc
gccgaaattaactatcaggccgcctgcctggcacgagcctgtgccgatgaatggaccgct
cgcacgccagagcagccgcgttacgtggccggggtgctggggccgaccaaccgtaccgcc
tctatttcaccgaacgtcaacgatccggcgttccgtaatgtttctttcgatgagctggtg
gaagcctaccgcgaatcgacgcgtgcgctggtggaaggcggtgtcgatctgatcatgatc
gaaaccatcttcgataccctgaacgccaaagccgccgccttcgcggtggaaaccgaattt
gaagccctgggcgttgcgctgccgatcatgatttccggcaccatcaccgacgcctccggc
cgtaccctgtcgggccagaccaccgaagccttctataactcaatgcgccacgtcaagccg
ctgagctttggcctgaactgtgcgctgggcccggacgaactgcgccaatacgtttctgag
ctgtcgcgtatctcggaaagctacgtcaccgctcaccccaacgccgggttacccaacgcc
ttcggcgaatacgatctggacgcgcaagaaatggcgaaacaggtcggcgagtgggcgaat
gccggcttcctgaatattatcggtggctgctgcggcaccacgccggaacacattgccgcg
atggtcaaggccgtggcgggtgtgccaccgcgtcaactgccggcgatcccggtcgcctgc
cgtctggccggccttgagccgttgaacattgacgccaagacgctgttcgtcaacgtgggc
gagcgtaccaacgtcaccggttccgcccgctttaagcggctgatcaaagaagagaaatac
agtgaagcgttagccgttgcccgccagcaggtggaaagcggcgcacagattatcgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatt
gccggtgaaccggatattgcccgcgtgccgatcatgatcgattcctccaaatggtcggtg
atcgagaaaggcctgaagtgtattcagggcaaaggcattgttaactctatctcgatgaaa
gagggcgaagaggcctttatccaccacgccaaactggtgcgccgctacggtgctgcggtc
gtggtgatggcatttgacgaggcaggccaggcggatacccgcgagcgcaagttcgagatt
tgtcgccgcgcttataaaatcctgaccgagcgcgtcggcttcccgccggaagacatcatt
tttgacccgaatatttttgccgtcgccaccggtatcgatgagcataacaactatgccgtc
gactttattgaagcctgtgccgacatcaaaacccacctgccgcatgcgatgatctccggt
ggggtgtccaacgtgtcgttctcattccgcggtaacgatccggtgcgtgaggcgatccac
gcggtattcctgtatcacgcgatccgcaacggcatggatatgggcatcgttaacgccggg
cagttggcgatctacgacgatctgagcgccgagttgcgcgatgcggtggaggacgtgatc
ctcaaccgccgcgacgacggcaccgagcgcctgctggagctggcggaaaaataccgcggc
agcaaagataacgaagtggcggtgcagcaggcggaatggcgcggctggccggtcgaaaaa
cggctggaatattcactggtcaaagggattaccgagtttatcgaactggataccgaagaa
gcgcgccagcgtgcggatcgcccgatcgaagtgatcgaagggccgctgatggcggggatg
aacgtggtcggtgacctgttcggcgaaggcaagatgttcctgcctcaggtggtgaaatcc
gcccgtgtgatgaagcaggcggtggcctatctggagccgtacatcgaggccagcaaggag
aaaggcacgacggcgggtaaaatcctgctggcgacggtgaagggcgatgtacacgacatc
ggcaaaaatatcgtcggcgtggtgttgcagtgcaacaactacgaaattgtcgatttgggc
gtgatggtgccgacggagaaaatcctgaaaaccgcgcgtgagcagaacgtcgatatcatc
ggcctgtcggggctgattaccccgtcgctggacgagatggtcaacgtggctaaagagatg
gagcgtcagggctttaccctgccgttgctgatcggcggtgccacgacgtccaaggcccat
accgcggtgaagattgagcaaaattacagtggctcaaccacctacgtgcaaaatgcctca
cgcaccgtgggtgtggtgtcggcactgctttccgccacccaacgcgacgatttcgtggcg
cgaacccgtaaagaatatgaaaccgtgcgcatccagcacgcgcgtaaaaagccgcgcact
ccgccggtcagcctgcaaaaagcgcgcgataacgccatggtgctggattgggaaagttat
cagccgccggtgccgaaacggttgggcgtttacccggttgaagccggtatagaaacgctg
cgtcattacatcgactggacgccgttctttatgacctggtcgctggcgggtaaatacccg
cgcattctggaagatgaagtggtgggtgaagaggccaaacggctgttcgccgacgccaac
cagatgctggactggcttgccgccaacggcagcctcaacccgcgcggtgtctatggcctg
ttcccggccaaccgcgttggtgacgatgtggaggtgtaccgcgacgaaaaccgtgatgag
gtgctggtggtcagccgccacctgcgccagcagacggaaaaaaccgacttcccgaactac
tgtttggcggactttgtcgcgccgaaaagcagtggcaaggccgactacttcggtgctttc
gcggtgaccggcggtctggaagaggatgacctggcggcggcctatgatgcgcagcacgat
gattacaataaaatcatggtgaaagcgctgtcggatcgtctggcggaggctttcgccgag
tacctgcacgagcaggtgcgcaagctgcactggggtttcgcggcggaagagaacctgagc
aacgaagagctgatccgcgaaaattatcagggcatccgcccggctccgggctatccggcc
tgcccggaacacaccgagaaagcggaaatctggcgcctgctggacgttaaccgccacacc
ggtatggtgttgaccgaatccttcgccatgtggccgggggcggcggtgtccggctggtac
tttagccacccgcaaagcaagtattttgcggtagcccagctccagcgcgatcaggtggaa
gactatgcggcgcgtaaaggcatgagcgtcagcgaggttgaacgctggctggcacccaac
ctcggctacgacgccgactga

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