Streptomyces rochei: SRO_2546
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Entry
SRO_2546 CDS
T06265
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
srj
Streptomyces rochei
Pathway
srj00020
Citrate cycle (TCA cycle)
srj00630
Glyoxylate and dicarboxylate metabolism
srj00785
Lipoic acid metabolism
srj01100
Metabolic pathways
srj01110
Biosynthesis of secondary metabolites
srj01120
Microbial metabolism in diverse environments
srj01200
Carbon metabolism
srj01210
2-Oxocarboxylic acid metabolism
Module
srj_M00009
Citrate cycle (TCA cycle, Krebs cycle)
srj_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
srj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SRO_2546
00630 Glyoxylate and dicarboxylate metabolism
SRO_2546
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SRO_2546
Enzymes [BR:
srj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SRO_2546
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SRO_2546
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SRO_2546
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SRO_2546
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
BBC93722
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All DBs
Position
2882699..2886346
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AA seq
1215 aa
AA seq
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MGLLRRLQAGRACHARAGGYCGRGGRSDPHSGAPGRSGARGPGGPKPAAAPAPAAAAPAA
PAAKTAPSPAKPAQPAQAPAQPQAKAAPATEAPAGPEQITLRGPAAAVAKNMDASLEMPT
ATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPAMNHSFTVKDG
KPTLVKPAHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRAREGKLT
MDDFTGVTVSLTNPGGLGTVHSVPRLMPGQAVIMGVGSMDYPAEFQGTSQDTLNKLGVSK
VMTLTSTYDHRVIQGAASGEFLRQVANLLLGENKFYDEIFEALRIPYEPVRWLKDIDASH
DDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDIVEHGLTLWDLEREFAVGG
FAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHAKPEREEQLRIL
RRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRL
NVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGANGTFTGLDGEQIKVSLVANPS
HLEAVDPILEGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRT
GGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFR
QAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEE
AEQALQDYQGQLEKVFTEVREATAQPAAGAPQEAQDGFPVAVPTAVSAEVVKRIAESQVN
IPEHITVHPRLQPQLQRRAAMVEDGTIDWGMGETLAIGSLLLDGTPVRLAGQDSQRGTFG
QRHAVLIDRETGEEYTPLQYLAEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEA
QFGDFVNGAQTVVDEFISSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQN
NMTVAMPTSPSNYFHLLRWQVHNPAHKPLVVFTPKSMLRLKAAASKAEEFTTGGFQPVIG
DATAEAAAVRRVVFCSGKVYYDLEAERKKRGATDTAIIRIERLYPLPGAELQAEVNKYPN
AEKYLWVQEEPANQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHSSSPAVGSAKR
HQAEQEQLVREVFEA
NT seq
3648 nt
NT seq
+upstream
nt +downstream
nt
gtgggacttcttcgccgattacaagccgggcgcgcctgccacgcccgcgccggcgggtac
tgcggccgcgggggtcgcagcgacccccactccggcgccccaggccgctccggcgcccgc
ggccccggcggcccgaagcccgccgccgccccggcgcccgctgcggccgctccggcggct
cccgcggcgaagacggccccctccccggccaagccggcgcagcccgcacaggcgcccgct
cagccgcaggcgaaggccgctcccgccaccgaggcccccgccggtcccgagcagatcact
ctgcgcggcccggccgccgcggtcgccaagaacatggacgcctcgctggagatgccgacc
gccacctcggtccgcgccgtcccggtgaagctgctgttcgacaaccgcatcgtcatcaac
aaccacctcaagcgcgcccgcggcgggaagatctccttcacgcacctcatcgggtacgcg
atggtgcaggccatcaaggccatgccggcgatgaaccactcgttcaccgtcaaggacggc
aagccgaccctggtcaagccggcccacgtcaacctcggtctcgccatcgacctggtcaag
cccaacggcgaccgccagctcgtcgtcgcggcgatcaagaaggccgagacgctgaacttc
ttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgaaggcaagctgacc
atggacgacttcaccggtgtcacggtctccctgaccaaccccggcggcctgggcaccgtg
cactccgtgccgcgtctgatgcccggccaggccgtgatcatgggcgtcggctccatggac
tacccggccgagttccagggcaccagccaggacaccctgaacaagctcggtgtctccaag
gtcatgaccctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgag
ttcctgcgccaggtcgccaacctgctgctcggcgagaacaagttctacgacgagatcttc
gaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcgtcccac
gacgacgacgtcaccaaggccgcgcgggtcttcgagctgatccactcctaccgggtccgc
ggccatgtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctg
gacatcgtcgagcacggcctcaccctgtgggacctggagcgcgagttcgccgtcggtggt
ttcgccggcaagtcgatgatgaagctgcgcgacatcctcggggtgctccgcgactcgtac
tgccgcaccaccggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatc
caggaccgggtcgagcgcggtcacgccaagccggagcgcgaggagcagctgcgcatcctg
cgccggctgaacgctgccgaggcgttcgagaccttcctccagacgaagtacgtcggccag
aagcgcttctccctggagggcggcgagtccgtcatcccgctgctggacgcggtcatcgac
tccgccgccgagtcccgcctggacgaggtcgtcatcggcatggcccaccgcggccgtctg
aacgtgctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggc
aacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccaat
ggcaccttcaccggcctggacggcgagcagatcaaggtctcgctggtcgccaacccctcc
cacctggaggcggtcgacccgatcctggagggcgtcgcccgcgccaagcaggacatcatc
aacaagggcggcacggacttcaccgtcctgccggtggcgatccacggcgacgcggccttc
gcgggccagggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcacc
ggcggcaccgtgcacatcgtcatcaacaaccaggtcggcttcacggcggcccccgagtcc
tcgcgttcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatcttccac
gtgaacggcgacgaccccgaggccgtcgtccgggtcgcgcggctggcgttcgagttccgc
caggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaac
gagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgc
tcggtgcgcaagctctacaccgagtccctgatcggtcgtggcgacatcaccctggaagag
gccgagcaggccctccaggactaccagggccagctggagaaggtcttcacggaggtccgc
gaggccaccgcgcagccggctgccggtgccccccaggaggcccaggacggcttcccggtc
gcggtcccgaccgccgtctccgccgaggtcgtcaagcggatcgccgagtcccaggtcaac
atccccgagcacatcaccgtgcacccgcggctccagccgcagctccagcgccgtgcggcg
atggtcgaggacggcaccatcgactggggcatgggcgagaccctggccatcggctccctg
ctgctggacggcaccccggtccgcctcgcgggccaggactcccagcgcggcaccttcggc
cagcgccacgcggtgctgatcgaccgggagaccggcgaggagtacaccccgctccagtac
ctcgccgaggaccaggcgcggctgaacgtctacaactcgctgctgtccgagtacgcggcc
atgggcttcgagtacggctactcgctcgcgcgtcccgacgcgctggtgatgtgggaggcc
cagttcggcgacttcgtcaacggcgcccagacggtcgtcgacgagttcatctcctcggcc
gagcagaagtggggccagacctccggcgtcgtcctgctgctgccgcacggctacgagggc
cagggcccggaccactcgtccgcgcgcccggagcggttcctccagctgtgcgcccagaac
aacatgacggtggccatgcccacctcgccgtcgaactacttccacctgctgcgctggcag
gtgcacaacccggcccacaagccgctggtcgtcttcaccccgaagtcgatgctgcgtctg
aaggccgccgcctccaaggcggaggagttcacgaccggcggcttccagccggtcatcggc
gacgcgaccgccgaggcggccgccgtccgcagggtcgtcttctgctccggcaaggtctac
tacgacctggaggccgagcgtaagaagcgcggcgccacggacacggcgatcatccgcatc
gagcgcctgtacccgctgccgggtgccgagctccaggcggaggtcaacaagtacccgaac
gccgagaagtacctgtgggtccaggaggagccggcgaaccagggtgcctggccgttcatc
gcgctcaacctgatcgatcacctcgacctggcggtcggcgcggacatcccggccggcgag
cggctgcggcgcatctcgcgcccgcactcctcgtccccggcggtgggttccgccaagcgc
caccaggccgagcaggagcagctggtgcgtgaggtgttcgaggcctaa
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