Streptomyces rectiverticillatus: FGW37_10145
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Entry
FGW37_10145 CDS
T06927
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
srk
Streptomyces rectiverticillatus
Pathway
srk00010
Glycolysis / Gluconeogenesis
srk00020
Citrate cycle (TCA cycle)
srk00620
Pyruvate metabolism
srk00785
Lipoic acid metabolism
srk01100
Metabolic pathways
srk01110
Biosynthesis of secondary metabolites
srk01120
Microbial metabolism in diverse environments
srk01200
Carbon metabolism
srk01210
2-Oxocarboxylic acid metabolism
Module
srk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
srk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FGW37_10145 (aceE)
00020 Citrate cycle (TCA cycle)
FGW37_10145 (aceE)
00620 Pyruvate metabolism
FGW37_10145 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FGW37_10145 (aceE)
Enzymes [BR:
srk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FGW37_10145 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QLE71915
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All DBs
Position
2342120..2344852
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AA seq
910 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLSERNLDSFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKVMQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNSTPDGQFQTYATETGAYIRDHFFGDDHRLR
KMVENMTDDQILHLGRGGHDHKKIYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKRFRDRLHIPIADKELESGLPPYYHPGRDSEEIQYMHDRRNSLGGYVP
TRVDRSKPLALPEDKVYASAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGVVSYDPAFGFEMAHIVKDGLRRMYGENAEDVFYYLTVYNEPIQHPAEPA
DVDADGILKGLYRFSQGEKGALPAQILASGVAVPWAIEAQKILAEEWDVKADVWSATSWN
ELRRDAIEAEEHNLLHPEEELRVPYVTQKLQGAEGPFVAVSDWMRAVPDQISRWVPGAYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKQGKVDRSLLKQAVDRYQLLDVTA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatcccgaagagacccaggagtggctcgactcgctcgacgcagccgtcgatgag
cgaggccgggaacgtgcccgctacctcatgcttcgcctgatcgagcgcgcacgcgagaag
cgcgtcgcggtgcccgagatgcgcagcacggactacgtcaacacgatcgcgaccaaggac
gagccgttcttccccggtaacgaggagatcgagcgcaagatcctcaacgcgacccgctgg
aacgcggccgtgatggtctcccgtgcccagcgccccggcatcggcgtcggcggccacatc
gccacgttcgcctcctccgcctccctgtacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctccccgggcatc
tacgcccgcgcgttcctcctggaccggctctccgagcggaacctggactccttccgccag
gagaagtcgaaggccccctacggcctctccagctacccgcacccgcgcctcatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggtgcgatctaccaggcc
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctccaagtcccacgtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgtccatcgcc
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcagcgcctcgac
ggcccggtccgcggcaacggcaaggtcatgcaggagctggagtcgcagttccgcggcgcc
ggctggaacgtgatcaagctggtctgggaccgctcctgggacccgctgctggcccaggac
cgcgacggcatcctggtcaacaagctcaacagcaccccggacggccagttccagacgtac
gccaccgagaccggtgcgtacatccgcgaccacttcttcggcgacgaccaccgtctgcgc
aagatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatctacgcggcgtacgcggcggccaaggcccacaagggccagccgaccgtg
atcctcgcgcagacggtcaagggctggaccctcggtccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcacggtcgaggacctcaagcgcttccgcgaccgcctccac
atcccgatcgccgacaaggagctggagtccggcctgccgccgtactaccacccgggtcgc
gactcggaggagatccagtacatgcacgaccgccgcaactcgctcggcggctacgtgccg
acccgcgtcgaccggtcgaagccgctggccctcccggaggacaaggtctacgcaagcgcc
aagaagggctccggccagcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggacgcgttcttcccgtcggccaagatctacaacccgctcggccag
cagtacgagtccgtggaccgcgagctgctgctcgcgtacaaggagtcgccgaccggccag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgcggcgggctcc
gcctacgcgacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcggc
ttccagcgcacgggcgaccagttctggcagatggccgaccagctgtcgcgcggcttcgtg
ctcggcgccacggcgggtcgcaccaccctgaccggtgagggcctgcagcacgccgacggc
cactcgcagctgctggcgtccaccaacccgggcgtcgtctcctacgaccccgcgttcggc
ttcgagatggcgcacatcgtcaaggacggtctgcgccggatgtacggcgagaacgccgag
gacgtcttctactacctgaccgtctacaacgagccgatccagcacccggccgagccggcg
gacgtggacgccgacggcatcctcaagggtctgtaccgcttctcgcagggcgagaagggc
gcgctcccggcccagatcctcgcctccggtgtcgcggtgccgtgggcgatcgaggcccag
aagatcctcgccgaggagtgggacgtcaaggcggacgtctggtcggcgacctcctggaac
gagctgcgcagggacgccatcgaggcggaggagcacaacctcctgcacccggaggaggag
ctccgcgtgccgtacgtcacgcagaagctccagggcgccgagggcccgttcgtggccgtg
tccgactggatgcgggccgttccggaccagatctcgcgctgggtgccgggtgcgtaccag
tcgctgggtgccgacggcttcggcttcgccgacacccgtggtgcggcccgtcgcttcttc
cacatcgacgcccagtcgatcgtcctggccgtgctcaccgagctggccaagcaggggaag
gtcgaccgctccctgctgaagcaggcggtggaccgctaccagctgctggacgtcacggcg
gccgacccgggcgccgcgggcggcgacgcgtaa
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