Streptomyces rectiverticillatus: FGW37_22210
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Entry
FGW37_22210 CDS
T06927
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
srk
Streptomyces rectiverticillatus
Pathway
srk00020
Citrate cycle (TCA cycle)
srk00630
Glyoxylate and dicarboxylate metabolism
srk00785
Lipoic acid metabolism
srk01100
Metabolic pathways
srk01110
Biosynthesis of secondary metabolites
srk01120
Microbial metabolism in diverse environments
srk01200
Carbon metabolism
srk01210
2-Oxocarboxylic acid metabolism
Module
srk_M00009
Citrate cycle (TCA cycle, Krebs cycle)
srk_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
srk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
FGW37_22210
00630 Glyoxylate and dicarboxylate metabolism
FGW37_22210
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FGW37_22210
Enzymes [BR:
srk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
FGW37_22210
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
FGW37_22210
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
FGW37_22210
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
FGW37_22210
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QLE73935
LinkDB
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Position
complement(4995946..4999755)
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AA seq
1269 aa
AA seq
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MSPQSPNTSSISTDQDGQGKSPADVFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GTAAAAPPQEVIEAAGGPAPAATTPAAPAAPAPAAPAAAAQPATAAPAAPAAPAAAAAAP
AAPAPAKPAVKAAPAKPAAAAKPAEPAAGPELVTLRGPAAAVAKNMNASLELPTATSVRA
VPVKLLFDQRIVINNHLKRARGGKVSFTHLIGYAMVQALKLMPSMNYSFTEKDGKPTLVK
PEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARVGKLTMDDFTG
VTASLTNPGGIGTVHSVPRLMPGQGLILGVGAMDYPAEFQGTSQDALNRMGISKVMTLTS
TYDHRVIQGAASGEFLRILAQLLLGENGFYDEIFEALRIPYEPVRWLKDIDASHDDDVTK
AARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSM
MKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHSKPEREEQLRILRRLNAA
EAFETFLQTKYVGQKRFSLEGGESVIPLLDSVLDAAAEARLDEVVIGMAHRGRLNVLANI
VGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVD
PVVEGIARAKQDIIGKAGTDFTVLPVQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHI
VINNQVGFTAPPESSRSSMYCTDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKD
VVIDLICYRRRGHNESDNPSFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQ
DYQGQLEKVFVEVRDADAATAPAAVPAPLGGFPAAVNTAISQEVLKRIAESQVTTPENVT
VHPRLVPQLQRRAASIEDGTIDWGMGETLAFGSLLMEGTPVRLAGQDSRRGTFGQRHAVL
VDRETGEDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFV
NGAQSIVDEFISSSEQKWNQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNNMTVAM
PTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTSGQFRPVIGDDTVAA
ADVRKVVFCSGKVYYDLAAERAKRGATDTALVRIERLYPLPGEELQAEIAKFPNAEKYIW
AQEEPANQGAWPFIALNLIDHLDLAVGADVPARERLRRISRPHSSSPAVGSAKRHQAEQQ
TLINEVFDA
NT seq
3810 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccaacacctcgagcatctcgaccgaccaagacgggcagggcaag
agccctgcagacgtattcggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtcgaccgagcctggtgggacttcttcgccgactacaagccg
ggcaccgcggcggcagcgccgccgcaggaggtgatcgaagccgcgggcggccccgccccg
gccgccaccacgcccgcggcgcccgccgcaccggccccggccgctccggccgccgccgcg
cagcccgccaccgccgccccggcggctccggccgctcccgccgccgctgcggccgccccg
gcggcccccgctccggcgaagcccgcggtcaaggccgcgcccgccaagccggcggccgcc
gcgaagccggccgagccggccgcgggccccgagctggtcaccctgcgtggtcccgccgct
gcggtcgcgaagaacatgaacgcctccctggagctgccgacggccacgtccgtccgcgcc
gtcccggtgaagctgctgttcgaccagcgcatcgtgatcaacaatcacctcaagcgcgcc
cgcggcggcaaggtctccttcacgcacctcatcggctacgccatggtgcaggcgctgaag
ctcatgccgtcgatgaactactccttcacggagaaggacggcaagcccaccctcgtcaag
cccgagcacgtcaacctcggcctggcgatcgacctggtcaagccgaacggtgaccgccag
ctcgtggtcgcggccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgccgcgcccgcgtcggcaagctgacgatggacgacttcaccggc
gtcaccgcctcgctgaccaaccccggcggcatcggcaccgtgcactccgtgccgcgcctg
atgcccggccagggcctgatcctcggcgtcggcgcgatggactaccccgccgagttccag
ggcacctctcaggacgccctgaaccgcatgggcatctccaaggtcatgaccctgacctcg
acgtacgaccaccgggtgatccagggcgccgcctccggcgagttcctgcggatcctggcc
cagctgctgctcggcgagaacggcttctacgacgagatcttcgaggcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaag
gccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgac
accgacccgctggagtaccgccagcgcaagcaccccgacctcgacatcaccgagcacggc
ctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttcgccggcaagtccatg
atgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcgtcgagcgc
ggccactccaagcccgagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgcg
gaggccttcgagaccttcctgcagacgaagtacgtcggccagaagcgcttctccctggag
ggcggcgagtccgtcatcccgctgctggactcggtgctggacgccgccgccgaggcgcgt
ctggacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtcctcgcgaacatc
gtcggcaagtcctacgcccagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctg
gacggcgagcagatcaaggtctcgctggccgccaacccctcccacctggagacggtcgac
ccggtcgtcgagggcatcgcccgcgccaagcaggacatcatcggcaaggcgggcacggac
ttcaccgtcctgccggtccagctgcacggcgacgcggccttcgcgggccagggcgtcgtc
gccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacatc
gtcatcaacaaccaggtcggcttcaccgcgccgccggagtcctcgcgctcgtcgatgtac
tgcaccgacgtcgcccggatgatcgaggcgccgatcttccacgtgaacggtgacgacccg
gaggccgtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttcaacaaggac
gtcgtcatcgacctgatctgctaccgccgccgcgggcacaacgagtcggacaacccctcg
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtac
accgagtcgctgatcggccggggcgacatcaccctggaggaggccgagcaggccctgcag
gactaccagggccagctggagaaggtcttcgtcgaggtccgcgacgcggacgcggccacg
gctccggccgccgtcccggccccgctgggcgggttcccggcggcggtgaacaccgcgatc
tcccaggaggtcctcaagcggatcgccgagtcgcaggtcaccacgcccgagaacgtcacg
gtgcacccgcgcctggtgccgcagctgcagcgccgcgccgccagcatcgaggacggcacg
atcgactggggcatgggcgagaccctcgccttcggttcgctgctgatggagggcaccccg
gtccggctcgccggccaggactcccgccgcggcaccttcggccagcgtcacgcggtgctc
gtcgaccgcgagaccggcgaggactacaccccgctgctctacctgtccgaggaccaggcc
cgcttcaacgtctacgactcgctcctcagcgagtacgcggcgatgggcttcgagtacggc
tactcgctggcccgcccggacgcgctggtgctgtgggaggcccagttcggtgacttcgtc
aacggcgcccagagcatcgtcgacgagttcatctcctcctccgagcagaagtggaaccag
acctccggcgtcacgctgctgctgccgcacggctacgagggccagggcccggaccactcc
tcggcccgcgtcgagcgcttcctgcagctgtgcgcgcagaacaacatgacggtcgccatg
ccgacgctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcaccac
aagccgctgatcgtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtcgaag
gcggaggagttcaccagcggccagttccgtccggtcatcggtgacgacacggtcgccgcg
gcggacgtccgcaaggtcgtcttctgctccggcaaggtctactacgacctggccgccgag
cgcgccaagcgcggcgccacggacacggccctcgtccgcatcgagcgcctctacccgctg
ccgggcgaggagctccaggccgagatcgccaagttcccgaacgccgagaagtacatctgg
gcgcaggaggagccggcgaaccagggtgcctggccgttcatcgcgctgaacctgatcgac
cacctggacctggccgtcggcgccgacgtcccggcccgcgagcggctgcggcggatctcc
cgtccgcactcctcgtccccggcggtcggctcggccaagcgtcaccaggccgagcagcag
acgctgatcaacgaggtgttcgacgcctga
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