Streptomyces roseirectus: IAG44_12895
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Entry
IAG44_12895 CDS
T07860
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sroi
Streptomyces roseirectus
Pathway
sroi00020
Citrate cycle (TCA cycle)
sroi00630
Glyoxylate and dicarboxylate metabolism
sroi00785
Lipoic acid metabolism
sroi01100
Metabolic pathways
sroi01110
Biosynthesis of secondary metabolites
sroi01120
Microbial metabolism in diverse environments
sroi01200
Carbon metabolism
sroi01210
2-Oxocarboxylic acid metabolism
Module
sroi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sroi_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sroi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
IAG44_12895
00630 Glyoxylate and dicarboxylate metabolism
IAG44_12895
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IAG44_12895
Enzymes [BR:
sroi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
IAG44_12895
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
IAG44_12895
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
IAG44_12895
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
IAG44_12895
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QNP70255
UniProt:
A0A7H0IBT9
LinkDB
All DBs
Position
3159723..3163499
Genome browser
AA seq
1258 aa
AA seq
DB search
MSSQSPSNGSSTSTEADQTGTNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAEPAAPAAAGTAAAGAAATTPTAPATPAPVPAAPAAPAATPAPQPAAAAPAPAPAPK
PKAAPVSTPAPSKEAPEGPELVTLRGPAAAVAKNMNASIEVPTATSVRAVPVKLLFDNRI
VINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPAHVNFGLAID
LVKANGDRQLVVAGIKKAETLGFFEFWQAYEDIVRRARDGKLTMDDFTGVTVSLTNPGGL
GTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAA
SGEFLRIVANLLLGENGFYDDVFKSLRIPYEPIRWLKDIDASHDNDVTKAARVFELIHSY
RVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSLMKLRDILGVLR
DSYCRTTGVEFMHIQDPKQRKWIQDRIERPHSKPEREEQLRILRRLNAAEAFETFLQTKY
VGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFRE
FEGNLDPKSMHGSGDVKYHLGAQGTFTGLDGEEITVSLVANPSHLEAVDPVLEGVARAKQ
DIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAA
PESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLLCYRRR
GHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLEKVFT
EVREATAQGPAGASADPQDGFPVATPTAISTEAVKRIAESQVNIPDHITAHPRLLPQLQR
RAAMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDRETAEEFTP
LNYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVVDEFI
SSAEQKWAQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQNNMTVAMPTLPSNYFHLL
RWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFRPVIGDTSVDPNAVRKVVFTAG
KVYYDLDAERQKRGITDTAIIRIERLYPLAGAELQAEIAKYPNAEKYLWAQEEPANQGAW
PFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLVREVFEA
NT seq
3777 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtcacagtcccccagtaacggatcgagcacctcgaccgaagcggaccaaacgggt
accaatcccgcggccgcgttcggaccgaacgagtggcttgtcgacgagatctatcagcag
tacctccaggacccgaattccgtggaccgggcctggtgggacttcttcgccgactacaag
ccgggggctgccgagccggccgctccggctgcggcgggtactgcggccgcgggggccgca
gcgaccacccccacggcgcctgccacacccgctcccgttcccgcggctcccgcggccccg
gcggcgaccccggctccccagccggccgccgccgcgcccgcccccgcacccgcacccaag
ccgaaggccgctcccgtgtcgacgcccgccccctcgaaggaagcccccgagggccccgag
ctggtcaccctgcgcggtccggccgccgccgtcgcgaagaacatgaacgcctccatcgag
gtccccacggcgacgtccgtgcgcgcggtcccggtgaagctgctcttcgacaaccgcatc
gtcatcaacaaccacctcaagcgcgcccggggcgggaagatctccttcacgcacctcatc
gggtacgcgatggtgcaggccatcaaggccatgccgtcgatgaactactccttcgcggag
aaggacggcaagccgacgctggtcaagccggcccacgtgaacttcggtctcgcgatcgac
ctggtgaaggccaacggcgaccgccagctcgtcgtcgccggcatcaagaaggccgagacg
ctcggcttcttcgagttctggcaggcgtacgaggacatcgtccgccgcgcccgcgacggc
aagctgacgatggacgacttcaccggcgtcaccgtctccctcaccaaccccggcgggctc
ggcaccgtccactccgtgccgcggctgatgcccggtcagtcggtcatcatgggcgtcggc
tccatggactacccggcggagttccagggcacctcgcaggacaccctgaacaagctcggc
atctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtcatccagggcgccgcc
tccggcgagttcctgcggatcgtcgcgaacctgctgctcggcgagaacggcttctacgac
gacgtcttcaagtcgctgcggatcccctacgagccgatccgctggctcaaggacatcgac
gcctcgcacgacaatgacgtcacgaaggccgcccgcgtcttcgagctgatccactcctac
cgggtgcgcggtcacgtgatggccgacaccgacccgctggagtaccagcagcgcaagcac
cccgacctggacatcaccgagcacggcctcaccctgtgggacctggagcgggagttcgcg
gtcggcgggttcgccggcaagtccctgatgaagctgcgcgacatcctcggcgtgctgcgc
gactcgtactgccgcaccaccggcgtcgagttcatgcacatccaggacccgaagcagcgc
aagtggatccaggaccgcatcgagcgcccgcactccaagccggagcgcgaggagcagctg
cggatcctgcgccgcctgaacgcggcggaagccttcgagacgttcctgcagaccaagtac
gtcggccagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcg
gtcatcgactccgccgccgaatcccggctcgacgaggtcgtcatcggcatggcccaccgc
ggccggctcaacgtgctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgag
ttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtcaagtaccacctg
ggcgcgcagggcacgttcaccggtctggacggcgaggagatcaccgtcagcctggtcgcg
aacccctcgcacctggaggccgtcgacccggtcctcgaaggtgtcgcgcgcgccaagcag
gacatcatcaacaagggcggcacggacttcaccgtcctgcccgtcgcgatccacggcgac
gcggccttcgcgggccagggcgtggtcgccgagacgctgaacatgtcgcagctgcgcggc
taccgcaccggcggcacggtccacgtcgtcatcaacaaccaggtcggcttcaccgccgcg
ccggagtcctcgcgctcctcgatgtacgccaccgacgtggcccgcatgatcgaggcgccg
atcttccacgtgaacggcgacgaccccgaggccgtcgtgcgcgtcgcgcggctcgcgttc
gagttccggcaggcgttcaacaaggacgtcgtcatcgacctgctgtgctaccgccgccgc
ggccacaacgagtcggacaacccggcgttcacgcagccgctgatgtacgatctgatcgac
aagaagcgctcggtgcgcaagctctacaccgagtcgctgatcgggcgcggcgacatcacg
ctggaagaggccgagcaggcgctccaggactaccaggggcagctggagaaggtcttcacg
gaggtccgcgaggccaccgcgcagggccccgccggcgcgtccgccgacccgcaggacggg
ttcccggtcgccacgccgaccgcgatctccaccgaggcggtcaagcggatcgccgagtcg
caggtcaacatcccggaccacatcacggcccacccccgcctgctgccgcagctccagcgc
cgggcggccatggtcgaggacgggacgatcgactggggcatgggcgagacccttgccatc
gggtcgctgctgctcgaaggcgtgccggtgcggctcgccgggcaggactcgcagcgcggt
acgttcggccagcgccacgcggtcatcatcgaccgtgagaccgccgaggagttcacgccg
ctgaactacctctcggaggaccaggcccggctcaacgtctacaactcgctgctctccgag
tacgcggccatgggcttcgagtacggctactcgctggcccgcccggacgcgctcgtcatg
tgggaggcgcagttcggtgacttcgtcaacggcgcgcagaccgtcgtcgacgagttcatc
tcctccgccgagcagaagtgggcgcagacgtccggcgtcacgctgctgctgccgcacggc
tacgagggccagggcccggaccactcgtccgcgcgcccggagcggttcctccagatgtgc
gcgcagaacaacatgacggtcgccatgccgacgctgccgtcgaactacttccacctcctg
cggtggcaggtgcacaacccgcaccacaagccgctggtcgtcttcacgccgaagtcgatg
ctgcgcctcaaggcggcggcgtcgaaggcggaggagttcacgtccgggcagttccgtccg
gtcatcggggacacctcggtcgacccgaacgccgtccgcaaggtcgtcttcaccgccggc
aaggtctactacgacctcgacgccgagcggcagaagcgcggcatcacggacacggcgatc
atccggatcgagcggctgtacccgctggcgggtgccgagctccaggcggagatcgccaag
taccccaacgccgagaagtacctctgggcccaggaagagccggcgaaccagggcgcctgg
cccttcatcgccctcaacctcatcgaccacctggacctggcggtcggcgcggacgtcccg
cacggggagcggctgcggcggatctcgcgtccgcacagctcgtcgcctgccgtcggctcg
gcgaagcgccaccaggcggagcaggagcagctggtccgcgaggtcttcgaggcgtga
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