Streptomyces sp. RPA4-5: HEP86_33755
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Entry
HEP86_33755 CDS
T10325
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00909
Sesquiterpenoid and triterpenoid biosynthesis
srpa01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
HEP86_33755 (shc)
Enzymes [BR:
srpa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
HEP86_33755 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
HEP86_33755 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
QIY58554
UniProt:
A0A6H1K7B1
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All DBs
Position
7590930..7592948
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AA seq
672 aa
AA seq
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MTATTDGSTGALPPRAPSASDATAEKTATPAPARTAVRQDTVDAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPKLTEAAARHIRGQQGADGTWATFYGGPG
ELSATIEAYVALRLAGDVPDAPHMARAAAWVRAEGGIAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRHPNPP
RPLAPATTWDGVFQRLDKALHVYHKVALPGLRRAAMRSAARWIVERQENDGCWGGIQPPA
VYSVIALHLCGYDLDHPVLRAGLDSLDRFAVWREDGTRMIEACQSPVWDTCLATIALADA
GVPADHPQLVKAAEWMLAEQIDRPGDWSVKRPQLPSGGWGFEFENDNYPDIDDTAEVVLA
LRRVRHPDPLRVDAAVRRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQEPDGSWFGRWGTNYLYGTGSVLPALA
AVGVPGSHPAVRRAVRWLERVQNDDGGWGEDQRSYQDKERWAGRGASTASQTAWALMALL
AAGERDSQPVRRGVRWLAATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRY
LGGGPGGVPVES
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggcactgccgccccgggccccctcggccagc
gatgccaccgctgagaagaccgccacaccagcgcccgcgcgcaccgccgtacggcaggac
acggtggacgccgcccggcgcgcgaccgcacgcgccaccgactatctgctgtccgtccag
gaccccgccggatggtggaagggcgacctcgagaccaacgtcacgatggacgccgaagac
ctgctgctccgtcagttcctgggaatccaggacccgaagctcaccgaagccgctgcccgc
cacatccgtgggcaacagggcgcggacggcacctgggccaccttctacggcgggcccggt
gaactctccgccaccatcgaggcctatgtcgccctgcggctcgccggggacgtccccgac
gcgccgcacatggcccgggccgccgcctgggtccgcgcggagggcgggatcgccgcggcc
cgggtcttcacccgcatctggctggcgctcttcggctggtggaagtgggacgacctgccc
caactgccgccggaactcctctacttccccaagtggttcccgctcaacatctatgacttc
gggtgctgggcgcggcagaccatcgtgccgctgaccatcgtctcggccaagcgcccggtc
cgcccggccccgttcgccctcgacgagctgcacaccgatccgcgtcaccccaacccgccg
cggccgctcgcccccgccaccacctgggacggcgtgttccagcgcctcgacaaggcgctg
cacgtctaccacaaggtcgccctgcccggtctgcgccgggccgcgatgcgctccgccgca
cgctggatcgtcgaacggcaggagaacgacggctgctggggcggtatccagccccccgcc
gtctactccgtcatcgccctgcacctctgcggctacgacctcgaccaccccgtgctgcgc
gccggtctggactccctcgaccggttcgccgtctggcgcgaggacggtacccggatgatc
gaggcctgccagtccccggtctgggacacctgcctggcgaccatcgcgctggccgacgcc
ggagtgcccgccgaccacccgcagctggtcaaggccgccgagtggatgctcgccgagcag
atcgaccggcccggcgactggagcgtcaaacgaccccaactcccctccgggggctggggt
ttcgagttcgagaacgacaactacccggacatcgacgacaccgcggaggtggtgctcgcg
ctgcgccgggtccggcaccccgatccgctgcgggtcgacgccgcggtccggcgcgcggtg
cgctggaacctcgggatgcagtcgaagaacggggcctggggcgccttcgacgtcgacaac
accagcccgttccccaaccggctgccgttctgcgacttcggggaggtcatcgacccgccg
tcggccgatgtcaccgcccatgtcgtcgagatgctcgccgacgtcggccgtacccacgac
ccgcgcacccgccgcgggatcgcctggctgctggccgaacaggaacctgacggctcgtgg
ttcggccgctggggcaccaactacctttacggcaccggatcggtgctccccgccctggcc
gcggtcggcgtccccggctcgcaccccgcggtccgccgggccgtgcgctggctggagcgg
gtgcagaacgacgacggcggctggggcgaggaccagcgctcctaccaggacaaggagcgg
tgggcggggcgcggtgcctcgaccgcctcacagaccgcctgggcgctgatggcgctgctc
gcggccggggagcgggacagccagccggtacggcgcggggtgcgctggctggccgcgacc
cagcgcgaggacgggtcctgggacgagccgcacttcaccggcaccggcttcccctgggac
ttctccatcaactatcacctgtaccgccaggtcttcccgctgacggccctgggccgctac
ctcggcgggggaccgggcggcgtaccggtggagtcctga
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