Serratia sp. AS12: SerAS12_4215
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Entry
SerAS12_4215 CDS
T01502
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
srs
Serratia sp. AS12
Pathway
srs00010
Glycolysis / Gluconeogenesis
srs00020
Citrate cycle (TCA cycle)
srs00620
Pyruvate metabolism
srs00785
Lipoic acid metabolism
srs01100
Metabolic pathways
srs01110
Biosynthesis of secondary metabolites
srs01120
Microbial metabolism in diverse environments
srs01200
Carbon metabolism
srs01210
2-Oxocarboxylic acid metabolism
Module
srs_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
srs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SerAS12_4215
00020 Citrate cycle (TCA cycle)
SerAS12_4215
00620 Pyruvate metabolism
SerAS12_4215
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SerAS12_4215
Enzymes [BR:
srs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SerAS12_4215
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AEF52263
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Position
complement(4510167..4512830)
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AA seq
887 aa
AA seq
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MSERLNNDVDPIETRDWLQAIESVIREEGVERAQFLIDQVLGEARKGGVSVAAGAAANNY
VNTIAVEDEPAYPGNLDLERRIRSAIRWNAVMTVLRASKKDLDLGGHMASFQSSATFYEV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTEDQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPISAIYQAKFLKYLEHRGLKNTSAQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFAGAGWQVLKVIWGGRWD
ELLRKDTSGKLIQLMNETLDGDYQTFKSKDGAYVREHFFGRFPETAALVKDMTDDEIWAL
NRGGHDPKKVFAALKKAQDTQGKPTVILAHTIKGYGMGETAEGKNIAHQVKKMNMEGVHH
FRDRFNVPVADADIEKLPYITFEKESEEYKYLHERRQALKGYVPTRLPAFTQKLEMPALE
DFSSLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAASSWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLVRMYGDAQENVYYYITTLNENYHMPAMPQGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREASQILAKDYGVGSDIYSVTSFTELARDGQDCERWNMLHP
TETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPASDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIEASVVADAIKKFDINPEKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttaaacaatgacgtggatccgatcgaaacccgcgactggctgcaggcg
atcgaatcggtcatccgtgaagagggtgttgagcgagctcagtttctgattgatcaggta
ttgggtgaagcccgtaaaggcggtgttagcgttgcagccggtgctgccgccaacaactac
gtcaacaccatcgcggtggaagacgaacctgcttacccaggcaacctggatctggaacgt
cgtatccgttcagccatccgctggaacgcggtaatgaccgttctgcgtgcatccaagaaa
gatctggacctgggcggccacatggcttccttccagtcttccgcgaccttctatgaagtc
tgcttcaaccacttcttccgtgcgcgcaacgagcaagacggcggcgatctggtttacttc
cagggccacatctctccaggcgtttacgcacgagccttccttgaaggccgcctgaccgaa
gaccaaatgaacaacttccgtcaggaagttcacggcaaaggcctgtcttcttacccgcat
ccgaaactgatgccggaattctggcagttcccgaccgtttccatgggcctgggcccaatc
agcgccatctatcaagcgaagttcctgaaatatctggaacaccgtggcctgaagaacacc
tctgctcaaaccgtttatgccttcctgggcgacggcgagatggacgaacctgaatccaag
ggcgcgatcaccatcgctacccgtgaaaaactggacaacctggtcttcgtcatcaactgt
aacctgcagcgtctggacggcccggtcaccggtaacggcaagatcatcaacgagctggaa
ggcatcttcgccggtgcaggctggcaggttctgaaagtgatttggggcggacgttgggat
gaactgctgcgtaaagacaccagcggcaaactgatccaactgatgaacgaaaccctggac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtacgcgagcacttcttcggc
cgcttcccggaaaccgctgctctggtcaaagacatgaccgacgacgaaatctgggcgctg
aaccgtggtggtcacgatccgaagaaagtctttgctgcactgaaaaaagcgcaggacacc
caaggcaaaccaaccgtgatcctggcccataccatcaaaggttacggcatgggtgaaacc
gcggaaggtaaaaacattgctcaccaggtgaagaaaatgaacatggaaggggttcaccac
ttccgcgatcgtttcaacgtgccggttgccgatgctgacatcgaaaaactgccgtacatc
accttcgagaaagagtctgaagagtacaaatacctgcacgaacgccgtcaggcgctgaaa
ggttatgtgccgactcgtctgccggccttcacccagaagctggaaatgccggctctggaa
gacttcagctcactgctggaagagcagaacaaagaaatctccaccactatcgctttcgta
cgtgccctgaacgtgatgctgaagaacaagtcgattaaagatcgcctggttccaatcatt
gccgacgaagcccgtaccttcggtatggaaggtctgttccgtcagatcggtatctacagc
ccgaacggtcagcagtacactccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagatcctgcaggaaggcatcaacgaactgggcgcagcctcttcatggttg
gccgcagcgacttcctacagcaccaacgatctgccaatgattccgttctacatctactat
tcgatgttcggtttccagcgtatcggtgacctgtgctgggcagcgggcgaccaacaggcg
cgcggcttcctgatcggcgggacttccggccgtaccaccctgaacggtgaaggtctgcag
cacgaagacggccacagccacattcagtctctgactatccctaactgtatctcttacgat
ccagcttacgcatacgaagtggctgtaatcatgcatgacggtctggtccgcatgtacggc
gacgcgcaggaaaacgtctactactacatcaccacgctgaacgaaaactaccacatgccg
gccatgccgcagggtgcggaagaaggtatccgtaaaggtatctacaagctggaaactctg
gaaggcagcaaaggtaaagtgcagttgctgggttcaggttccattctgcgtcacgtgcgt
gaagcttcgcagatcctggcgaaagactacggcgtgggttctgacatctacagcgtgact
tccttcaccgaactggcgcgcgatggccaggactgcgagcgttggaacatgctgcaccca
accgaaaccccacgcgtgccttacatcgctcaggtgatgaacgatgcgcctgcggttgcg
tctaccgactacatgaagctgttcgcagaacaggttcgtacttacgttccagccagcgat
tatcgcgttctgggtactgacggcttcggtcgttcagacagccgcgaaaacctgcgtcac
cactttgaagtcgatgcttcttacgttgtggttgctgctctgggtgaactggctaaacgc
ggtgaaatcgaagcttctgtggtagctgatgcgattaagaaattcgacatcaacccagaa
aaagtcaacccgcgtctggcataa
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