Streptomyces rutgersensis: F0345_07420
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Entry
F0345_07420 CDS
T08623
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
srug
Streptomyces rutgersensis
Pathway
srug00010
Glycolysis / Gluconeogenesis
srug00020
Citrate cycle (TCA cycle)
srug00620
Pyruvate metabolism
srug00785
Lipoic acid metabolism
srug01100
Metabolic pathways
srug01110
Biosynthesis of secondary metabolites
srug01120
Microbial metabolism in diverse environments
srug01200
Carbon metabolism
srug01210
2-Oxocarboxylic acid metabolism
Module
srug_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
srug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
F0345_07420 (aceE)
00020 Citrate cycle (TCA cycle)
F0345_07420 (aceE)
00620 Pyruvate metabolism
F0345_07420 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F0345_07420 (aceE)
Enzymes [BR:
srug01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
F0345_07420 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QNE80968
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Position
1804298..1807030
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AA seq
910 aa
AA seq
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MASGPDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRQRARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEVERKILNATRWNAAAMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAYLLDRFTEEQLDGFRQ
EKSKAPNGLSSYPHPRSMPDFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTTASHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGLLVNKLNTTPDGQFQTYATETGSYIREHFFGTDQRLR
SMVENMTDDQILHLGRGGHDHRKIFAAFAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVADLKGFRDRLHLPIPDKELEDGLPPYFHPGPDSEEIQYMHDRRRALGGYVP
TRVVRAKPLALPADKTYASVKKGSGQQAIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPAVVAYDPAYGYEIAHIVQDGLRRMYGPDSEDVFYYLTVYNEPIQHPAEPE
DVDVEGILKGVHRLRAGDSGEIPAQILASGVAVPWALEAQRILAQEWDVRADVWSATSWN
ELRREAIDVERHNLLHPEEEQRVPYVTRKLSGSEGPFVAVSDWMRAVPDQISRWVPGTYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAREGKVDRAAPKQAMDRYQLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggacccgatcgcaacccgatcatcattggcggcctgcccagccaggtcccg
gacttcgatcccgaagagacccaggaatggctggactccctcgacgccgccgtcgacgag
cgcggccggcagcgggcgcgctatctcatgctccgcctgatcgagcgggcccgcgagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtcaacacgatcgcgaccaaggac
gagccgttcttccccggcaacgaggaagtcgagcggaagatcctcaacgcgacccggtgg
aacgccgcggcgatggtctcccgcgcgcagcgccccggcatcggcgtcggcggccacatc
gcgaccttcgcctcctccgcctcgctgtacgacgtcggcttcaaccacttcttccgtggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggcatc
tacgcccgcgcctacctcctggaccgcttcaccgaggagcagctcgacggcttccgccag
gagaagtcgaaggcaccgaacggactctccagctatccgcacccgcgctccatgccggac
ttctgggagttccccaccgtctccatgggcctcggcccgctcggggctatcttccaggcg
cggatgaaccgctacatggaggcgcggggcatcgccgacaccaccgcctcgcacgtgtgg
gcttttctcggcgacggcgagatggacgagccggagtcgctcgggcagctctccatcgcg
gcccgtgaggggctcgacaacctcaccttcgtcgtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctcgagtcgcagttccgcggcgcg
ggctggaacgtgatcaagctcgtctgggaccgttcctgggacccgctgctcgctcaggac
cgcgacggcctgctggtcaacaagttgaacaccaccccggacggtcagttccagacctac
gcgaccgagacgggctcctacatccgcgagcacttcttcggcaccgaccagcggctgcgc
agcatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
caccggaagatctttgcggccttcgccgcggccaaggcccacaagggtcagccgacggtg
atcctggcgcagaccgtcaagggctggaccctcgggcccaacttcgagggccgcaacgcc
acacatcagatgaagaagctgaccgtcgccgacctcaagggcttccgcgaccggctccac
ctgccgatccccgacaaggagctggaggacggtctgccgccgtacttccacccgggcccc
gactcggaggagatccagtacatgcacgaccgccggcgcgcgctcggcgggtacgtgccg
acccgggtggtgcgggccaagccgcttgcactgccggccgacaagacctacgccagcgtg
aagaagggctcgggtcagcaggccatcgccacgacgatggccttcgtccgcctcctcaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgccccggacgagtac
cggaccttcggcatggactccttcttccccagcgccaagatctacaacccgctggggcag
cagtacgagtcggtcgaccgtgaactgcttctggcctacaaggagtcgccgaccgggcag
atgctccacgacggcatctcggaggcgggctgcacggcgtcgctgatcgcggccggctcc
gcctacgccacccacggcgaaccgctgatccccgtctacgtcttctactcgatgttcggg
ttccagcgcaccggcgaccagttctggcagatggcggaccagctggcccgcgggttcgtg
ctcggcgccaccgcgggacggaccaccctgaccggtgaggggttgcagcacgccgacggc
cactcccagcttctcgcctccaccaacccggccgtcgtggcctacgacccggcctacggc
tacgagatcgcccacatcgtccaggacggtctgcggcggatgtacgggcccgacagtgag
gatgtcttctactacctcaccgtctacaacgaacccatccagcaccccgcggagccggag
gacgtcgacgtcgagggcatcctcaagggcgtgcaccggctgcgagccggcgactccggc
gagatcccggcgcagatcctggcctccggcgtggccgtgccgtgggccctggaggcccag
cggatccttgcgcaggagtgggacgtgcgggcggacgtgtggtcggcgacctcctggaac
gagctgcgccgggaggcgatcgacgtggagcgccacaacctgctgcaccccgaggaggag
cagcgggtcccgtacgtgacgcggaagctgtccggctcggaaggccccttcgtggcggtc
tccgactggatgcgcgcggtccccgaccagatctcccgctgggtgcccgggacctaccag
tcgctcggcgccgacggcttcggcttcgcggacacccggggcgccgcccggcggttcttc
cacatcgacgcgcagtcgatcgtgctggcggtgctgacggagctggcccgtgagggcaag
gtcgaccgggccgcgcccaagcaggcgatggaccggtaccagttgctcgacgtggccgcc
gcggacccgggagcggcgggcggcgacgcctga
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