Streptomyces rutgersensis: F0345_20465
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Entry
F0345_20465 CDS
T08623
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
srug
Streptomyces rutgersensis
Pathway
srug00020
Citrate cycle (TCA cycle)
srug00630
Glyoxylate and dicarboxylate metabolism
srug00785
Lipoic acid metabolism
srug01100
Metabolic pathways
srug01110
Biosynthesis of secondary metabolites
srug01120
Microbial metabolism in diverse environments
srug01200
Carbon metabolism
srug01210
2-Oxocarboxylic acid metabolism
Module
srug_M00009
Citrate cycle (TCA cycle, Krebs cycle)
srug_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
srug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
F0345_20465
00630 Glyoxylate and dicarboxylate metabolism
F0345_20465
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F0345_20465
Enzymes [BR:
srug01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
F0345_20465
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
F0345_20465
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
F0345_20465
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
F0345_20465
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QNE83195
UniProt:
A0A6A0BSM5
LinkDB
All DBs
Position
complement(4854790..4858584)
Genome browser
AA seq
1264 aa
AA seq
DB search
MSPQSPSNSSVSTDQAGQAKSPAAAFGSNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGGGAAPVETAAPSAATSPAPAKPAPAAKAPEAKPAAAPQAAAPAKPAAKAPAEKAAPAK
TAPAKTAPAKPAAKAAEPAAAAEGPEYVTLRGPSAAVAKNMSASLELPTATSVRAVPVKL
LFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNNSFAQKDGKPTLVKPEHIN
LGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFSGVTASL
TNPGGIGTVHSVPRLMPGQSVILGVGAMEYPAEFQGTSQDTLNKLGVSKVMTLTSTYDHR
VIQGAASGEFLRIVANLLLGENEFYDDIFKALRIPYEPVRWLKDIDASHDDDVTKAARVF
ELIHSYRVRGHVMADTDPLEYHQRKHPDLDINEHGLTLWDLERTFAVGGFAGKSMMKLRD
ILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGPGKPEREEQLRILRRLNSAEAFET
FLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGKSY
AQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQITVSLTANPSHLEAVDPVMEG
VVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQ
VGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVGRLAFEFRQAFNKDVVIDL
ICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQ
LEKVFTEVREATSHPVQHEPEGPEAEFPVAVQTAVSAEVVKRIAESQVNIPERVTVHPRL
LPQLQRRAAMVEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRET
GDDFTPLLYLSDNQARYNVYDSLLSEYAAMGFEYGYSLARPESLVLWEAQFGDFVNGAQT
VVDEFISSAEQKWGQHSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPS
NYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAASSKAEEFTTGGFRPVIGDDSVDASQVRK
VVLCAGKVYYDLEAERQKRGVTDTAIIRVERLYPLPGAELQAEIAKYPNAEKFLWAQEEP
ANQGFWPFIALNLIDHLDLGVGADLPAAERLRRISRPHSSSPAVGSAKRHQAEQAQLVAE
VFDA
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaattcgagcgtctcgaccgaccaagcggggcaggccaag
agtcctgccgccgccttcgggtcgaacgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccc
ggcggaggtggcgccgctcccgtggagaccgcggccccgtcggcggcgacctcgcccgct
ccggccaagcccgccccggcggccaaggcccccgaggcgaagccggccgccgccccgcag
gccgcggcccccgcgaagcccgcggcgaaggccccggccgagaaggcggcgcccgccaag
accgctcccgccaagaccgccccggccaagcccgccgcgaaggccgccgagccggccgcc
gccgcggagggcccggagtacgtcacactgcgtggcccctcggccgcggtcgcgaagaac
atgagtgcctcgctggaactgcccacggccacgtccgtgcgcgcggtgccggtcaagctc
ctcttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcccggggcgggaagatc
tccttcacgcacctgatcggctacgccatggtgcaggccatcaaggccatgccgtcgatg
aacaactccttcgcgcagaaggacggcaagccgacgctggtcaagcccgagcacatcaac
ctcgggctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtcgtcgcggcc
atcaagaaggccgagaccctcaacttcttcgagttctggcaggcgtacgaggacatcgtc
cgccgtgcccgggacaacaagctgacgatggacgacttctccggcgtcaccgcctcgctg
accaacccgggcggcatcggcaccgtccactcggtgccgcgcctgatgcccggccagtcg
gtgatcctcggcgtgggcgcgatggagtacccggcggagttccagggcacctcccaggac
accctgaacaagctcggcgtctccaaggtcatgaccctgacgtcgacctacgaccaccgg
gtcatccagggcgccgcctccggcgagttcctgcggatcgtcgcaaacctgctgctcggc
gagaacgagttctacgacgacatcttcaaggcgctgcgcatcccctacgagccggtccgc
tggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcccgcgtcttc
gagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctcgag
taccaccagcgcaagcaccccgacctcgacatcaacgagcacgggctgacgctctgggac
ctggagcgcaccttcgcggtcggcggcttcgccggcaagtcgatgatgaagctccgcgac
atcctcggcgtcctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatc
caggacccgaagcagcgcaagtggatccaggaccgggtggagcgcggtccgggcaagccc
gagcgcgaggagcagctgcgcatcctgcgtcggctcaacagcgccgaggcgttcgagacc
ttcctgcagaccaagtacgtcggccagaagcggttctcgctggagggcggcgagtccgtc
atcccgctgctcgacgcggtcctcgactcggcggccgagtcgcgcctggacgaggtcgtc
atcggcatggcccaccgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcgtac
gcgcagatcttccgggagttcgagggcaacctcgacccgaagtcgatgcacggctccggc
gacgtcaagtaccacctgggcgccgagggcaccttcacgggcctggacggcgagcagatc
acggtctccctcaccgccaacccctcccacctggaggcggtcgacccggtgatggagggc
gtggtccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctgccc
gtcgccctgcacggcgacgccgccttcgcgggccagggcgtcgtggccgagacgctcaac
atgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaaccag
gtcggtttcaccgccgcgccggagtcctcgcgctcctcgatgtacgccaccgacgtggcc
cgcatgatcgaggcgccgatcttccacgtgaacggtgacgacccggaggccgtcgtccgc
gtcggacggctcgccttcgagttccgccaggcgttcaacaaggacgtcgtcatcgacctg
atctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccgctg
atgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtcgctgatc
ggccggggcgacatcaccctggaggaggcggagcaggcgctccaggacttccagggccag
ctggagaaggtcttcaccgaggtccgcgaggccacctcgcacccggtgcagcacgagccg
gagggccccgaggcggagttcccggtcgcggtccagaccgcggtctccgccgaggtcgtc
aagcggatcgccgagtcgcaggtcaacatccccgagcgggtcaccgtccacccccgtctg
ctgccgcagctccagcgccgcgcggcgatggtcgaggacggcacgatcgactggggtatg
ggcgagaccctggccatcggttcgctgctgatggagggcaccccggtgcgcctcgccggc
caggactcgcgccgcggcaccttcggccagcgccacgcggtcctcatcgaccgggagacc
ggcgacgacttcacgccgctgctgtacctctcggacaaccaggcccgctacaacgtctac
gactcgctgctctcggagtacgcggcgatgggcttcgagtacggctactcgctggcccgt
ccggagtcgctggtgctgtgggaggcccagttcggtgacttcgtcaacggcgcgcagacc
gtcgtggacgagttcatctcctcggccgagcagaagtggggccagcactccggtgtgacc
ctcctgctgccgcacggctacgagggccagggcccggaccactcctcggcccgtccggag
cggttcctccagctctgcgcgcagaacaacatgacggtcgcgatgccgaccctcccgtcg
aactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtggtc
ttcacgccgaagtcgatgctgcgcctgaaggccgcctcgtccaaggcggaggagttcacg
acgggcggcttccgcccggtcatcggcgacgactcggtggacgcctcgcaggtccgcaag
gtcgtcctgtgcgccggcaaggtctactacgacctggaggccgagcggcagaagcgcggc
gtcacggacaccgcgatcatccgcgtcgagcggctgtacccgctgccgggtgcggagctc
caggcggagatcgccaagtacccgaacgccgagaagttcctgtgggcccaggaggagccg
gcgaaccagggcttctggccgttcatcgcgctcaacctgatcgaccacctggacctgggt
gtcggtgccgacctcccggcggccgagcggctgcggcgcatctcgcgtccgcactcctcg
tccccggcggtcggttcggccaagcgccaccaggccgagcaggcccagttggtcgccgag
gtcttcgacgcctga
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