Streptomyces reticuli: TUE45_05792
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Entry
TUE45_05792 CDS
T04246
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
srw
Streptomyces reticuli
Pathway
srw00020
Citrate cycle (TCA cycle)
srw00630
Glyoxylate and dicarboxylate metabolism
srw00785
Lipoic acid metabolism
srw01100
Metabolic pathways
srw01110
Biosynthesis of secondary metabolites
srw01120
Microbial metabolism in diverse environments
srw01200
Carbon metabolism
srw01210
2-Oxocarboxylic acid metabolism
Module
srw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
srw_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
srw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
TUE45_05792 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
TUE45_05792 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TUE45_05792 (kgd)
Enzymes [BR:
srw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
TUE45_05792 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
TUE45_05792 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
TUE45_05792 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
TUE45_05792 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CUW31055
LinkDB
All DBs
Position
I:complement(6491513..6495310)
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AA seq
1265 aa
AA seq
DB search
MSPQSPSNSSISTDDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPG
APATPAPAGTAATGAAETTTTAQKPAAAPAPQAAAPAAPAAPKPAAAPAPAAKAPAPAPA
KPAQPAQAPAQPKAKPAPAKEAPEGPELITLRGPSAAVAKNMDASLEMPTATSVRAVPVK
LLFDNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYGVKDGKPTLIKPAHV
NLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVS
LTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGVSKVMTLTSTYDH
RVIQGAASGEFLRTVANLLLGENGFYDDIFEALRIPYEPVRWLRDIDASHDDDVTKAARV
FELIHSYRVRGHVMADTDPLEYKQRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKLR
DILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHSKMEREEQLRILRRLNAAEAFE
TFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKS
YAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLE
GVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINN
QVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVID
LICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQG
QLEKVFTEVREATSQPAAGDVQAPQDGFPVAVPTAVSSEVVKRIAESQVNIPDHITVHPR
LQPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGTPVRLAGQDSQRGTFGQRHAVLIDRE
TGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNGAQ
TVVDEFISSAEQKWNQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSP
SNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFRPVIGDSTVDPAAVR
KVVFCAGKVYYDLEAERAKRGVTDTAIIRIERLYPLPGAELQAEVNKYPNAEKYLWAQEE
PANQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHSSSPAVGSAKRHQAEQEQLVR
EVFDA
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgaccaagccgggaagaac
cccgcggctgcgttcggtccgaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtagaccgcgcctggtgggacttcttcgccgattacaagccgggg
gctcctgccaccccggctccggcgggtactgcggccacgggggccgcagagaccaccacc
acggctcagaagcccgccgcggccccggccccccaggccgccgccccggccgcccccgcg
gcgccgaagcccgccgcggctccggcccccgcggccaaggctccggcccccgccccggcc
aagccggcgcagcccgcacaggcgcccgctcagccgaaggcgaagcccgccccggcgaag
gaggcccccgagggccccgagctgatcaccctgcgtggtccgtccgccgcggtcgccaag
aacatggacgcctcgctggagatgccgaccgccacctcggtccgcgccgtcccggtgaag
ctgctgttcgacaaccggatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaag
atctccttcacgcacatcatcgggtacgcgatggtgcaggccatcaaggccatgccgtcg
atgaactggtcgtacggcgtcaaggacggcaagccgaccctgatcaagccggcccacgtc
aacctcggcctggccatcgacctggtcaagccgaacggtgaccgccagctcgtcgtggcc
gccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatc
gtccgccgcgcccgtgacggcaagctgacgatggacgacttcaccggtgtcacggtctcc
ctgaccaaccccggcggcctcggcaccgtccactccgtgccgcggctgatgcccggccag
tccgtgatcatgggcgtcggctccatggactacccggcggagttccagggcaccagccag
gacaccctgaacaagctcggcgtctccaaggtcatgacgctcacgtcgacctacgaccac
cgggtcatccagggcgccgcctccggcgagttcctgcgcaccgtcgcgaacctgctgctc
ggcgagaacggcttctacgacgacatcttcgaggcgctgcggatcccctacgagccggtc
cgctggctgcgggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcccgcgtc
ttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctg
gagtacaagcagcgcaagcaccccgacctggacatcgtcgagcacggcctcaccctgtgg
gacctggagcgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaagctgcgc
gacatcctcggcgtgctccgcgactcgtactgccgcaccaccggcatcgagttcatgcac
atccaggaccccaagcagcgcaagtggatccaggaccgcgtggagcgcccgcactccaag
atggagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgcggaggccttcgag
accttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggcgagtcc
gtcatcccgctgctcgacgcggtcatcgactccgcggccgagtcccgcctggacgaggtc
gtcatcggcatggcccaccgcggccgcctgaacgtgctggccaacatcgtcggcaagtcg
tacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctcc
ggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcag
atcaaggtctccctggtcgcgaacccctcccacctggaggccgtcgacccggtcctggag
ggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtgctg
ccggtggcgatccacggcgacgcggccttcgcgggccagggcgtggtggccgagaccctg
aacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaac
caggtcggcttcaccgcggcccccgagtcctcgcgttcctccatgtacgcgacggacgtg
gcccgcatgatcgaggccccgatcttccacgtgaacggcgacgaccccgaggccgtcgtg
cgcgtcgcgcggctggccttcgagttccgccaggcgttcaacaaggacgtggtgatcgac
ctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccg
ctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctg
atcggtcgcggcgacatcaccctggaagaggccgagcaggccctccaggactaccagggc
cagctggagaaggtcttcaccgaggtccgcgaggctacgtcccagccggccgccggggac
gtccaggcgccccaggacggcttcccggtcgcggtcccgaccgcggtctcctcggaggtc
gtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcaccgtccacccgcgt
ctccagccgcagctgcagcgccgggcggcgatggtcgaggacggcacgatcgactggggc
atgggcgagaccctggccatcggctccctgctgctggagggcaccccggtccggctcgcg
ggccaggactcccagcgcggcaccttcggccagcgccacgcggtgctgatcgaccgggag
accggcgaggagtacaccccgctgcagtacctctccgaggaccaggcccggctcaacgtc
tacaactcgctgctctccgagtacgcggcgatgggcttcgagtacggctactcgctggcc
cgccccgacgcgctcgtgatgtgggaagcgcagttcggtgacttcgtcaacggcgcgcag
acggtcgtggacgagttcatctcgtcggccgagcagaagtggaaccagacctccggcgtc
gtcctgctgctgccgcacggctacgagggccagggcccggaccactcgtccgcgcgtccc
gagcgcttcctccagctgtgcgcgcagaacaacatgacggtcgcgatgccgacgtcgccg
tcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtc
gtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcctcgaaggcggaggagttc
acgagcgggcagttccgcccggtcatcggcgacagcacggtcgacccggccgcggtccgc
aaggtcgtgttctgcgccggcaaggtctactacgacctggaggccgagcgggccaagcgc
ggggtcacggacacggcgatcatccgcatcgagcggctgtacccgctgccgggtgccgag
cttcaggcggaggtcaacaagtacccgaacgccgagaagtacctgtgggcgcaggaggag
ccggcgaaccagggtgcctggccgttcatcgcgctgaacctgatcgaccacctggacctg
gcggtcggcgcggacatcccggccggcgagcggctgcggcgcatctcgcgtccgcacagc
tcgtccccggccgtgggttccgctaagcggcaccaggcggagcaggagcagctggtgcga
gaggtcttcgacgcctga
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