Streptomyces reticuli: TUE45_07304
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Entry
TUE45_07304 CDS
T04246
Symbol
shc
Name
(GenBank) Squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
srw
Streptomyces reticuli
Pathway
srw00909
Sesquiterpenoid and triterpenoid biosynthesis
srw01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
srw00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
TUE45_07304 (shc)
Enzymes [BR:
srw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
TUE45_07304 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
TUE45_07304 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
PGM1_C
Motif
Other DBs
NCBI-ProteinID:
CUW32554
LinkDB
All DBs
Position
I:8274803..8276833
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AA seq
676 aa
AA seq
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MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVQEAAARAARRATDFLLARQDTQGWWKG
DLETNVTMDAEDLLLRQFLGILDDKTTQAAAKFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWIRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPQPLAPLAS
WDGVFQRLDKVVRGYRKVAVRRLRKAAMNSAARWIVERQENDGCWGGIQPPAVYSIIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLERVQNDDGGWGEDLRSYQDAKEWSGRGASTASQTAWALMALLAAGERGSE
AVERGIRWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
ILPAKTATAASRADGS
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggcgaccttgccgtcccgcgctgccgcggcc
agcgacaccaccctcaccacccccgaggcggccggggtacaagaagccgccgcacgcgcc
gcacggcgcgccaccgacttcctgctcgcccggcaggacacccagggctggtggaagggc
gacctggagaccaacgtcaccatggacgccgaggatctgctgctccgccagttcctgggc
atcctggacgacaagacgacgcaggccgccgcgaagttcatccgcggcgagcagcgcgag
gacggcacctgggccaccttctacggcggacccggcgaactgtccaccaccatcgaggcg
tacgtcgccctgcggctggccggcgacgcgcccgacgccccgcacatggcgaaggcgtcc
gcctggatccgcgaacgcggcggcatcgccgcctcccgggtcttcacccggatctggctc
gccctgttcggctggtggaagtgggaggacctgcccgaactcccgccggagctgatctac
ttccccacctggttcccgctcaacatctacaacttcggatgctgggcccggcagaccatc
gtgccgctgaccatcgtctccgccaagcgcccggtgcgtcccgcccccttcgcgctggac
gagctgcacaccgacccggcccaccccaacccgccgcagccgctcgccccgctggcgagc
tgggacggcgtcttccagcggctcgacaaggtggtccgcggctaccgcaaggtcgccgtg
cgcaggctccgcaaggccgcgatgaactcggcggcccgctggatcgtcgagcgccaggag
aacgacggctgctggggcggcatccagccgccggccgtgtactcgatcatcgccctccat
ctgctcggctacgacctggagcacccggtgctgcgcgagggcctcgcctcgctcgaccgc
ttcgccgtctggcgcgaggacggcgcgcggatgatcgaggcctgccagtccccggtgtgg
gacacctgcctggccaccatcgccctcgtggacgccggtctgccggtcgaccatccgcaa
ctggtcaaggcggccgactggatgctcggcgaggagatcgtccggcccggcgactgggcc
gtgcggcggccccaactgcccccgggcggctgggcgttcgagttccacaacgacaactac
ccggacatcgacgacaccgccgaggtcgccctcgcgctgcgccgggtccggcaccacgac
ccggagcgggtggaccgggcgatcgggcgggccgtccgctggaacctcggcatgcagtcg
aagaacggcgcctggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcaccgcgcacgtc
gtggagatgctcgccgccgagggcctggcccacgacccgcgcacccggcgcggcatcgac
tggctgctcgccgaacaggaaccggacggctcgtggttcggccgctggggggtcaactac
ctctacggcaccgggtcggtcgtccccgcgctcaccgcggccgggctgcccggctcgcac
ccggcgatccggcgggccgtggcctggctggagcgcgtccagaacgacgacggcggctgg
ggcgaggacctgcgctcctaccaggacgccaaggagtggagcggccggggcgcctccacc
gcctcgcagacggcgtgggcgctgatggcgctgctcgccgcgggggagaggggctccgag
gccgtcgagcgcggcatccggtggctggccgagacccagcgggaggacggcagctgggac
gagccgtacttcaccggcaccggcttcccctgggacttctccatcaactaccacctctac
cggcaggtgttcccgctcaccgcgctcggccgctacctgcacggggaccccttcgagcgc
atcctgccggccaagaccgcgacggccgcgtcccgggccgacgggagctga
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