KEGG   Sus scrofa (pig): 100152910
Entry
100152910         CDS       T01009                                 
Symbol
CYP1A2
Name
(RefSeq) cytochrome P450 1A2
  KO
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00140  Steroid hormone biosynthesis
ssc00232  Caffeine metabolism
ssc00380  Tryptophan metabolism
ssc00591  Linoleic acid metabolism
ssc00830  Retinol metabolism
ssc00980  Metabolism of xenobiotics by cytochrome P450
ssc00982  Drug metabolism - cytochrome P450
ssc01100  Metabolic pathways
ssc05204  Chemical carcinogenesis - DNA adducts
ssc05207  Chemical carcinogenesis - receptor activation
ssc05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100152910 (CYP1A2)
   00591 Linoleic acid metabolism
    100152910 (CYP1A2)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    100152910 (CYP1A2)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100152910 (CYP1A2)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    100152910 (CYP1A2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100152910 (CYP1A2)
   00982 Drug metabolism - cytochrome P450
    100152910 (CYP1A2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100152910 (CYP1A2)
   05207 Chemical carcinogenesis - receptor activation
    100152910 (CYP1A2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100152910 (CYP1A2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ssc00199]
    100152910 (CYP1A2)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     100152910 (CYP1A2)
Cytochrome P450 [BR:ssc00199]
 Cytochrome P450, animal type
  CYP1 family
   100152910 (CYP1A2)
SSDB
Motif
Pfam: p450 FANCI_HD1
Other DBs
NCBI-GeneID: 100152910
NCBI-ProteinID: NP_001153086
Ensembl: ENSSSCG00000001901
UniProt: F1SJ26 A0A4X1TKW5
LinkDB
Position
7:complement(58779529..58786155)
AA seq 516 aa
MTLFQPSLFSATELLLASAIFCLVFWVVRTWQPQVPKGLKSPPGPWGWPLLGHVLTLGKS
PHLALARLSQCYGDVLQIRIGCTPVLVLSGLDTIRQALVRQGDDFKGRPNLYSFTLVTDG
QSMTFNPDSGPVWAARRRLAQKALNTFSIASDPASSSSCYLEDHVSKEAECLLGKFQELM
AGPGHFDPYDHIVVSVGRVIGAMCFGKGFPQSSEEMFSIVKNSHEFVETASSGNPVDFFP
ILRYLPSPTLQRFKSFNQRLLQFLRKMVQERYRDFDKNCIQDITSALFKHSEENSSTSGG
LISQEKTINLVNDIFGAGFDTITTAISWSLLYLVTYPEIQKKIQKELDTVIGRARRPRLS
DRPQLPYMEAFILELFRHTSFVPFTIPHSTTRDTTLNGFYIPKERHVLVNQWQVNHDPKL
WGDPSEFRPERFLTADGTAIHKTMSEKVILFGMGKRRCIGEVLAKWEVFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHAHCKHFQAHLRFPIK
NT seq 1551 nt   +upstreamnt  +downstreamnt
atgacattattccagcccagtctcttctcagccacagagctgctcctggcctctgccatc
ttctgccttgtattctgggtggtcaggacctggcagcctcaggtccccaaaggcctgaag
agtccaccagggccctggggctggcccctgctcgggcacgtgctgaccttgggcaagagc
ccacacctggccctggcaaggctgagccagtgctatggagatgtgctgcaaatccgcatt
ggctgcacccctgtgctggtgctcagcggcctggacaccatccggcaggccctggtgcgg
cagggcgacgatttcaagggacggcccaacctctacagcttcactctggtcactgatggc
cagagcatgaccttcaacccagactctggaccagtgtgggctgcccgtcggcgcctggcc
cagaaggctcttaacaccttctccattgcctcagacccggcttcctcctcctcctgctac
ctggaggatcatgtgagcaaggaggctgagtgcctccttggcaagttccaggagctgatg
gcagggcctgggcactttgatccctatgaccacattgtggtgtcagtgggccgtgtcatc
ggtgccatgtgcttcgggaagggcttcccacagagcagtgaggagatgttcagcatcgtg
aagaacagtcatgaatttgtggagaccgcctcatccgggaaccccgtggacttcttcccc
atccttagatatctgcccagccctactctgcaaagattcaagagtttcaatcaaaggctc
ctgcaattcctgaggaaaatggtccaggagcgctatcgggactttgacaagaactgtatc
caggacatcacaagcgccctattcaagcacagcgaggagaattccagcaccagcggtggc
ctcatctcccaggagaagaccatcaaccttgtcaatgacatttttggagccggatttgat
acaattaccacagccatctcctggagccttttataccttgtgacatatcctgagatacag
aagaagatccagaaggagctggacacagtgattggccgggcgcggcggccccggctctcc
gacagaccccagctgccctatatggaggccttcatcctggagctcttccgacacacctcc
ttcgttcccttcaccatccctcacagcacaacaagggacacgacactgaatggcttctac
atccccaaggaacgccatgtcctcgtaaaccagtggcaggttaatcatgacccgaagctg
tggggggacccatccgagttccggccagagagattcctcactgccgatggcactgccatc
cacaagaccatgagtgagaaagttattctcttcggcatgggcaagcgccggtgcataggg
gaggtcctggccaagtgggaggtcttcctcttcctggccatcttgctgcagcagctagag
ttcagcgtgcctccaggcgtgaaagtggacctaacccccatctacgggctgaccatgaag
catgcccactgcaagcatttccaggcacatctgcgtttccccatcaaatga

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