Sus scrofa (pig): 100512268
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Entry
100512268 CDS
T01009
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00140
Steroid hormone biosynthesis
ssc00980
Metabolism of xenobiotics by cytochrome P450
ssc01100
Metabolic pathways
ssc05204
Chemical carcinogenesis - DNA adducts
Module
ssc_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100512268 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
100512268 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
100512268 (HSD11B1L)
Enzymes [BR:
ssc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
100512268 (HSD11B1L)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
100512268
NCBI-ProteinID:
XP_003123133
Ensembl:
ENSSSCG00000030546
UniProt:
A0A8D1J5T3
A0A480X741
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Position
2:complement(73288989..73294677)
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AA seq
293 aa
AA seq
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MDPVKAMKVLLLTGLGALFFAYYWGDNFDPASLRGARVLLTGASAGVGEELAYHYARLGS
HLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPDVPERVVQFALDKLGGLDYLVLN
HLGAAPAGTRARSAQAIRWLLQVNFISYVQLTSLALPSLTDSKGSLVVVSSLLGRVPTSF
SSPYSAAKFALDSFFDSLRRELDMQDVNVAITMCVLGLRDHASAAEGVRGVTRAKAAPGP
KAALAVIRGSATRASGVFYPWRFHLLCLLRGWLPHPRAWFIRQELNITASAAA
NT seq
882 nt
NT seq
+upstream
nt +downstream
nt
atggacccagtgaaggccatgaaggtgctgctcctcacggggctgggagccctgttcttc
gcctattattggggtgacaattttgacccagccagcctccgtggagcccgtgtgctgtta
acaggagccagcgcaggcgttggggaggaactggcatatcactatgcgcgcctgggctca
cacctggtgctcactgcccacaccgaggctctcctgcagaaagtggtagggaactgccgg
aagctgggcgctcccaaggtcttctacatcgctgcggacatggcctcccccgacgtgccc
gagcgcgtggtgcagttcgctctggacaagctgggagggctggactacctggtgctgaac
catctcggcgccgccccggcaggcacgcgggcccgcagcgcccaggcgatacgctggctc
ttgcaggtgaactttataagttacgtgcaactgacttcgttggcgctgcccagtctgact
gacagtaagggctccctggtggtggtgtcttctttgctaggccgcgtgcccacatccttc
tctagcccctactcggcggccaagttcgcgctggacagcttcttcgactctcttcggcga
gagctggacatgcaagatgtgaacgtggccatcaccatgtgtgtcctgggcctccgagat
catgcttcagccgctgaaggagtcaggggtgtcacgagggccaaggcggccccagggccc
aaggcagccctggctgtgatccgtggcagtgctacacgggcctccggtgtcttctaccca
tggcgcttccacctgctctgcctgcttcggggctggctgccacacccgagggcctggttc
atccgccaggagctcaacatcactgcctctgctgctgcctga
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