Sus scrofa (pig): 100512686 Help Entry 100512686         CDS       T01009                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism ssc  Sus scrofa (pig) Pathway ssc04022   cGMP-PKG signaling pathway ssc04068   FoxO signaling pathway ssc04081   Hormone signaling ssc04140   Autophagy - animal ssc04150   mTOR signaling pathway ssc04151   PI3K-Akt signaling pathway ssc04152   AMPK signaling pathway ssc04211   Longevity regulating pathway ssc04213   Longevity regulating pathway - multiple species ssc04722   Neurotrophin signaling pathway ssc04910   Insulin signaling pathway ssc04920   Adipocytokine signaling pathway ssc04923   Regulation of lipolysis in adipocytes ssc04930   Type II diabetes mellitus ssc04931   Insulin resistance ssc04932   Non-alcoholic fatty liver disease ssc04935   Growth hormone synthesis, secretion and action ssc04960   Aldosterone-regulated sodium reabsorption ssc05010   Alzheimer disease ssc05206   MicroRNAs in cancer ssc05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ssc00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100512686 (IRS1)    04022 cGMP-PKG signaling pathway     100512686 (IRS1)    04151 PI3K-Akt signaling pathway     100512686 (IRS1)    04152 AMPK signaling pathway     100512686 (IRS1)    04150 mTOR signaling pathway     100512686 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     100512686 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100512686 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100512686 (IRS1)    04923 Regulation of lipolysis in adipocytes     100512686 (IRS1)    04920 Adipocytokine signaling pathway     100512686 (IRS1)    04935 Growth hormone synthesis, secretion and action     100512686 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100512686 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     100512686 (IRS1)   09149 Aging    04211 Longevity regulating pathway     100512686 (IRS1)    04213 Longevity regulating pathway - multiple species     100512686 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100512686 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     100512686 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100512686 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100512686 (IRS1)    04932 Non-alcoholic fatty liver disease     100512686 (IRS1)    04931 Insulin resistance     100512686 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  100512686 NCBI-ProteinID:  NP_001231418 Ensembl:  ENSSSCG00000025729 UniProt:  C3S7K3 LinkDB All DBs Position 15:complement(128245846..128307321) Genome browser AA seq 1241 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAGPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPN GHYILPRGGNGHRCLPGAGLGTSPALTGEEAGPASDLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRMPNYRHSAFVPTHSYPEEGLEMHPLERRGGHHR QDTSSLHTDDGYMPMSPGVAPVPGTRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVES SSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EESARHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQPH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQPPQPALLHPPEPKSPGEYVNIEF GGDQPGYLSGPVASHSAPSVRCSSQLQPAPREENTGAEEYMNMDLGPGRRAIWQESAGVQ PGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPISYADMRTGIVV EEASLPGATAAAPSASSATSASSAAPQGAGELAACSSLLGGPQGPGGLSAFTRVNLSPNR NQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTVPFGGGAAVGGGGGGSSSTEAVKRH SSASFENVWLRPGELGGAPKELAQMCGAAGGLENGLNYIDLDLVKNFKQRPQERPPQPQP PPPPPPHQPLGNSESSSTSRSSEDLSAYASISFQKQPEDRQ NT seq 3726 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctcccgagacggatggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgctttttcgtgctgcgggcggccagcgaggctgggggc cccgcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggcggattccaagaac aagcacctggtggccctctacacccgggacgagcactttgccatcgcggcggacagcgag gccgaacaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac cacgacggggccgcaggccctggggcgggaggcggtgggggcagctgcagtggcagctct ggcctcggcgaggctggggaggacttgagctatggggacgtgcccccaggacccgccttc aaggaggtttggcaggtgatcctgaaacccaaaggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagtttcgtgaagctgaactcggag gcggcggctgtggtgctgcagctgatgaacatcaggcgctgtggccactcagagaacttc ttcttcatcgaagtgggccgttctgcagtgacgggacccggggagttttggatgcaggtg gatgattctgtggtggcccagaatatgcatgagacaatcctggaggccatgcgggccatg agcgatgagttccgccctcgaagcaagagccagtcctcctctaactgctccaaccccatc agtgtacctctgcgcaggcaccacctcaacaaccctccgcccagccaggtggggctgacc cgccgctcacgcacagagagcatcactgccacctccccggccagcttggtgggcgggaag cagggctccttccgcgtccgtgcgtccagtgatggcgaaggcaccatgtctcgccccgcc tctgtggatggcagtcctgtgagccctagcaccaacaggactcacgcccaccggcatcga ggcagctcccggctgcacccgcctcttaaccacagccgctctattcccatgccttcttct cgctgctcaccctccgccaccagcccggtcagcctgtcgtccagcagcaccagcggccat ggctccacctcggactgtctcttcccgcggcggtctagtgcttctgtgtccgggtccccc agtgacggcggtttcatctcttccgatgagtatggctctagcccctgtgatttccgaagc tccttccgcagtgtcacgccagattccctgggccacaccccgcccgcccgcggtgaggag gagctgagcaactacatctgcatggggggcaagggggcctccaccctcgctgcccccaat ggccactacattttgcctcggggtggcaatggccaccgctgcctcccaggagctggcttg ggcacgagcccagccctgaccggggaggaagcaggccctgcatctgatctggataaccgg ttccgaaagcggactcactctgctggcacatcccctactatttcccaccagaagacccca tcccagtcctctgtggcttccattgaggaatatacagagatgatgccggcctacccacca ggaggtggcagtggaggccggatgcccaactaccggcactccgccttcgtgcccacccac tcctaccctgaggagggtctggaaatgcaccccttggagcggcgtgggggtcaccaccgc caagacacctccagcctccacaccgatgatggctacatgcccatgtccccaggagtagcc ccagtgcccggcacccgaaagggcagtggggactacatgcccatgagccccaagagcgtg tctgccccgcagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat ggctacatgatgatgtcccccagcggcagctgctctcctgacattggaggtggtcccagc agcgggggcagcagcagcggtgccgccccttctgggagcagctatggcaagttatggaca aatggggtagggggccaccactctcacgccctgccacaccccaaactccctgtggagagc agtagtggcaagctcttgtcttgtacaggtgactacatgaacatgtcgccagtgggggac tccaacaccagcagcccttccgactgctactatggccccgaagatccccagcacaagcca gtcctctcctactactcgttgccaaggtccttcaagcacacgcagcgccccggggagctg gaggagagcgccaggcaccagcacctccgcctttcctccagctccggtcggcttctctat gctgcggcagcagaagattcgtcgtcatccaccagcagcgacagcctgggcgggggatac tgtggggctaggcccgagcccggcctcccgcatctccatcatcaggtcctgcagccccat ctgcctcgaaaggtggacacagcagcccagaccaacaaccgcctggctcggcccacgagg ctgtccctgggggatcccaaggccagcaccttacctcgggcccgagagcagccgccgcag ccggccctgctgcaccctccggaacccaaaagtccaggggaatatgtgaatattgaattt gggggcgatcagccgggctacttatcaggcccggtggcgtcccacagcgcgccttcggtg agatgttcatcgcagctccagccagctcccagagaagagaacactggcgccgaagagtac atgaacatggacctggggccaggccggagggcgatctggcaggagagcgctggggtccag cctggcagggtgggccccgcccccccgggagctgctagcgtgtgcaggccgacccgggcg gtgcccagcagccggggtgactacatgaccatgcagatgggttgtccccgtcagagctac gtggacacctcgccagtggcccccatcagctatgccgatatgcggaccggcatcgtcgtg gaggaggccagccttcccggggccacagcggctgctccctcggcgtcctcggccacctct gcttcctccgccgcgccccaaggagcaggggagctggcggcctgctcttccctgctgggg ggcccgcagggacccgggggcctgagcgccttcacacgggtgaatctcagtcccaaccgc aaccagagtgccaaagtgatccgtgccgaccctcaagggtgcaggaggcggcacagctcc gagaccttctcctcgacacccagtgccacccgggcgggcaacacggtacccttcggaggg ggagctgcagtcgggggcggcggtggtggcagcagcagcactgaggctgtgaaacgccac agctctgcctccttcgagaacgtgtggctgaggcctggggagcttgggggagcccccaag gagctggcccagatgtgcggagcagctgggggtttggagaatggtcttaactacatagac ctggatttggtcaagaacttcaaacagcgccctcaagagcgcccccctcaaccgcagcct cctccaccccctcctcctcatcagcctctgggcaacagtgagagcagctccaccagccgc tccagcgaggatttaagcgcctatgccagcatcagtttccagaagcagccagaggaccgt cagtag

DBGET integrated database retrieval system