Sus scrofa (pig): 100624934 Help Entry 100624934         CDS       T01009                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ssc  Sus scrofa (pig) Pathway ssc00230   Purine metabolism ssc01100   Metabolic pathways ssc01522   Endocrine resistance ssc04015   Rap1 signaling pathway ssc04020   Calcium signaling pathway ssc04022   cGMP-PKG signaling pathway ssc04024   cAMP signaling pathway ssc04062   Chemokine signaling pathway ssc04072   Phospholipase D signaling pathway ssc04081   Hormone signaling ssc04082   Neuroactive ligand signaling ssc04114   Oocyte meiosis ssc04211   Longevity regulating pathway ssc04213   Longevity regulating pathway - multiple species ssc04261   Adrenergic signaling in cardiomyocytes ssc04270   Vascular smooth muscle contraction ssc04371   Apelin signaling pathway ssc04540   Gap junction ssc04611   Platelet activation ssc04713   Circadian entrainment ssc04714   Thermogenesis ssc04720   Long-term potentiation ssc04723   Retrograde endocannabinoid signaling ssc04724   Glutamatergic synapse ssc04725   Cholinergic synapse ssc04727   GABAergic synapse ssc04750   Inflammatory mediator regulation of TRP channels ssc04911   Insulin secretion ssc04912   GnRH signaling pathway ssc04913   Ovarian steroidogenesis ssc04914   Progesterone-mediated oocyte maturation ssc04915   Estrogen signaling pathway ssc04916   Melanogenesis ssc04918   Thyroid hormone synthesis ssc04921   Oxytocin signaling pathway ssc04923   Regulation of lipolysis in adipocytes ssc04925   Aldosterone synthesis and secretion ssc04926   Relaxin signaling pathway ssc04927   Cortisol synthesis and secretion ssc04928   Parathyroid hormone synthesis, secretion and action ssc04934   Cushing syndrome ssc04935   Growth hormone synthesis, secretion and action ssc04970   Salivary secretion ssc04971   Gastric acid secretion ssc04972   Pancreatic secretion ssc04976   Bile secretion ssc05032   Morphine addiction ssc05142   Chagas disease ssc05146   Amoebiasis ssc05163   Human cytomegalovirus infection ssc05166   Human T-cell leukemia virus 1 infection ssc05200   Pathways in cancer ssc05207   Chemical carcinogenesis - receptor activation ssc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ssc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100624934 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100624934 (ADCY1)    04371 Apelin signaling pathway     100624934 (ADCY1)    04020 Calcium signaling pathway     100624934 (ADCY1)    04072 Phospholipase D signaling pathway     100624934 (ADCY1)    04024 cAMP signaling pathway     100624934 (ADCY1)    04022 cGMP-PKG signaling pathway     100624934 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100624934 (ADCY1)    04081 Hormone signaling     100624934 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100624934 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     100624934 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100624934 (ADCY1)    04062 Chemokine signaling pathway     100624934 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     100624934 (ADCY1)    04923 Regulation of lipolysis in adipocytes     100624934 (ADCY1)    04912 GnRH signaling pathway     100624934 (ADCY1)    04913 Ovarian steroidogenesis     100624934 (ADCY1)    04915 Estrogen signaling pathway     100624934 (ADCY1)    04914 Progesterone-mediated oocyte maturation     100624934 (ADCY1)    04921 Oxytocin signaling pathway     100624934 (ADCY1)    04926 Relaxin signaling pathway     100624934 (ADCY1)    04935 Growth hormone synthesis, secretion and action     100624934 (ADCY1)    04918 Thyroid hormone synthesis     100624934 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     100624934 (ADCY1)    04916 Melanogenesis     100624934 (ADCY1)    04925 Aldosterone synthesis and secretion     100624934 (ADCY1)    04927 Cortisol synthesis and secretion     100624934 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100624934 (ADCY1)    04270 Vascular smooth muscle contraction     100624934 (ADCY1)   09154 Digestive system    04970 Salivary secretion     100624934 (ADCY1)    04971 Gastric acid secretion     100624934 (ADCY1)    04972 Pancreatic secretion     100624934 (ADCY1)    04976 Bile secretion     100624934 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     100624934 (ADCY1)    04727 GABAergic synapse     100624934 (ADCY1)    04725 Cholinergic synapse     100624934 (ADCY1)    04720 Long-term potentiation     100624934 (ADCY1)    04723 Retrograde endocannabinoid signaling     100624934 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100624934 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     100624934 (ADCY1)    04213 Longevity regulating pathway - multiple species     100624934 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     100624934 (ADCY1)    04714 Thermogenesis     100624934 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100624934 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     100624934 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100624934 (ADCY1)    05163 Human cytomegalovirus infection     100624934 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     100624934 (ADCY1)    05142 Chagas disease     100624934 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     100624934 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100624934 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100624934 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100624934 (ADCY1) Enzymes [BR:ssc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100624934 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF7246 Motif Other DBs NCBI-GeneID:  100624934 NCBI-ProteinID:  XP_020934320 Ensembl:  ENSSSCG00000016726 UniProt:  A0A8D1SM94 LinkDB All DBs Position 18:complement(50043572..50143549) Genome browser AA seq 1136 aa AA seqDB search MAGAPRGRGGGGGGGGGGAGESGGAERAAGPAGRRGLRACEEEFACPELEALFRGYTLRL EQAATLKALAVLSLLAGALAVAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQV PQLQQVGQLALLFSLTFALLCCPFALGGPAGAHAGVAAVPAAAEQGVWQLLLVTFVSYAL LPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRLLAE RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY DVWSNDVTLANVMEAAGLPGKVHITKSTLACLNGDYEVEPGHGHERNSFLKTHNIETFFI VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKR RALRTASEKLRNRSSFSTNVVHATPGTRVNRYIGRLLEARQMELEMADLHFFTLKYKQAE RERKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCVCFLVACVLYLH ITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWTWSSSPNGSLVVLSSGGRA PMLPAPPCESAPHALLCGLVGTLPLVTFLRVSSLPKMILLAVLTTSYILVLELSGYTKAV GGGAVSGRSFEPILAILLFSCALALHARQVDIKLRLDYLWAAQAEEERDDMERVKLDNKR ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLR LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAKKCISSHLSTLADFA IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARSLNSERKMC PYGRAGLQARPATGHPPVPPAAGLPVRAGLGAVQGTGVVPCPPGQHLPPRVAGKEA NT seq 3411 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggaggcggcgcgggc gagtctgggggcgccgagcgggcggcagggccggctggccggcgcgggctgcgggcgtgc gaagaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg gagcaggcggccacgctgaaggcactggcggtgctcagcctgctggcgggcgcgctggct gtggccgagctgctgggcgcgcctgggcccgcgcccggcctggccaagggctcgcacccc gtgcactgcgtgctcttcttggcgctgctcgtggtcaccaacgtccgctcgctgcaggtg ccccagctgcagcaggtcggccagctggcgctgcttttcagcctcaccttcgcgctgctc tgctgtcccttcgcgctcggcggccccgccggggcccacgccggggtggcagcggtgccg gcggcagccgagcagggcgtctggcagcttcttttggtcaccttcgtgtcctatgccctg ctgcccgtgcgcagcctgctggccatcggttttgggctcgtggtggccgcctcgcacttg ctggtcacggctaccctggtccccgccaagcgcccacgtctctggaggacgctcggtgcc aacgccctgctcttcctgagcgtgaacatgtacggggtctttgtgaggctcctggccgag cgctcccagaggaaggccttcctgcaggcccggaactgcatcgaggaccggctgcggctg gaggatgagaacgagaagcaggagcggctgctcatgagtctcctgccccggaatgttgcc atggagatgaaggaagacttcctgaagccccccgagaggattttccacaagatttacatt cagcggcatgacaatgtgagcatcctctttgcagacatcgtgggcttcacgggcttggcg tcgcagtgcacggcccaggagctggtgaaactcctcaacgagctcttcggcaagtttgat gaactagccacggagaaccactgccgccgcatcaagatcctgggagactgctactactgc gtgtcgggcctcactcagcccaagaccgaccacgcccactgctgcgtggagatgggcctg gacatgatcgacaccatcacgtccgtggctgaggccactgaggtggatctgaacatgcgt gtggggctgcacaccgggagggtcctctgtggggtcctgggcctgcgcaagtggcagtac gacgtgtggtccaacgacgtgaccctggccaacgtcatggaagccgccgggctgcctggg aaggttcacatcaccaagagcaccctggcgtgtctgaacggggactacgaggtggagccc ggccacggccacgagaggaacagttttctgaaaactcacaacatcgagacttttttcatc gtgccctcccatcggcgaaagatatttccggggctgattctctcagacataaaaccagcc aagaggatgaagttcaagaccgtgtgctacctgctggtgcagctgatgcactgccggaag atgttcaaggcggagatccctttctccaacgtcatgacctgcgaggacgacgacaagcgg agggcgctgagaacagcctcggagaaactcagaaaccgctcgtctttctccaccaatgtc gtccacgccacccccgggacacgcgtcaacaggtacatcggccgcctcctggaagcccgc cagatggagctggagatggcagacctgcacttcttcaccctcaagtacaagcaggctgag cgagagcggaagtaccaccagctgcaggacgagtatttcaccagcgccgtggttctggcc ctcatcctggccgccttattcggccttgtctaccttctaatcatcccgcagagcgtggct gtcctgctcctgctggtgttctgcgtctgcttcctggtagcctgtgtcctgtatctacac atcacccgtgtccagtgttttccagggtgcctgacgatccagatccgcacagtcttatgt atcttcatagtggtcctgatctactccgtggcccaaggatgcgtggtgggctgcctgcct tggacctggagctccagccccaacgggtccctggtggtcctgtcatcggggggccgggcc cccatgctgcccgccccgccctgcgagtctgcgccgcacgccctgctctgcggcctcgtg ggcaccctcccgctggtcacgttcctgcgcgtctcctccctgccgaaaatgatcctgctt gccgtgctcaccacgtcctacatcctggtcctggagctcagcgggtacacgaaggccgtg gggggcggcgccgtctctgggcgcagcttcgagcccatcttggccatcctgctgttctca tgtgcgctggccttgcacgcccggcaggtggatatcaagctgcggctggactacctctgg gcagctcaggccgaggaggagcgggacgacatggagagggtgaagctggacaacaagagg atccttttcaacctcctgccggcccacgtggcccagcacttcctcatgtccaacccccgc aacatggacctgtactaccagtcctactcgcaggtgggggtcatgtttgcctccatcccc aacttcaacgacttctacatcgagctggacggtaacaacatgggggtggagtgcctgcgc ctcctcaacgagatcattgccgacttcgacgagctcatggacaaggacttttacaaggac ctggagaagatcaagaccatcggaagcacctacatggctgctgtggggctggcgcccacg gccggggccaaggctaagaaatgcatctcctcccatctcagcacgttggcggactttgcc attgagatgtttgatgtcttggatgagatcaactaccagtcttacaacgacttcgtgctc cgtgtgggcattaacgttggccccgtggtggccggggtgatcggggcccgcaggccgcag tacgacatttggggaaacaccgtcaacgtggccagtcggatggacagcaccggcgtccag ggcagaatccaggtgaccgaggaagttcaccggctgctgcgacggggcacgtaccgtttt gtgtgccgaggcaaagtcagcgtcaagggcaagggtgagatgctgacatacttcctggaa ggcaggaccgatggaaacggctcccaagctaggtccctgaactcagagcggaaaatgtgt ccctacggaagagccggcctccaggccagaccggccacgggccaccccccagtgccccca gcagccggcctccccgtcagagccgggctgggggctgtgcagggcacgggggtcgtcccc tgccccccaggccagcacctgccccccagagtggctgggaaggaggcttag

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