Sus scrofa (pig): 397445
Help
Entry
397445 CDS
T01009
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc04022
cGMP-PKG signaling pathway
ssc04024
cAMP signaling pathway
ssc04062
Chemokine signaling pathway
ssc04071
Sphingolipid signaling pathway
ssc04270
Vascular smooth muscle contraction
ssc04310
Wnt signaling pathway
ssc04360
Axon guidance
ssc04510
Focal adhesion
ssc04520
Adherens junction
ssc04530
Tight junction
ssc04611
Platelet activation
ssc04670
Leukocyte transendothelial migration
ssc04810
Regulation of actin cytoskeleton
ssc04921
Oxytocin signaling pathway
ssc05132
Salmonella infection
ssc05135
Yersinia infection
ssc05163
Human cytomegalovirus infection
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
397445 (ROCK2)
04071 Sphingolipid signaling pathway
397445 (ROCK2)
04024 cAMP signaling pathway
397445 (ROCK2)
04022 cGMP-PKG signaling pathway
397445 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
397445 (ROCK2)
04520 Adherens junction
397445 (ROCK2)
04530 Tight junction
397445 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
397445 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
397445 (ROCK2)
04670 Leukocyte transendothelial migration
397445 (ROCK2)
04062 Chemokine signaling pathway
397445 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
397445 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
397445 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
397445 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
397445 (ROCK2)
05205 Proteoglycans in cancer
397445 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
397445 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
397445 (ROCK2)
05135 Yersinia infection
397445 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
397445 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
397445 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ssc03036
]
397445 (ROCK2)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
397445 (ROCK2)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
397445 (ROCK2)
Chromosome and associated proteins [BR:
ssc03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
397445 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
397445
NCBI-ProteinID:
XP_013843390
Ensembl:
ENSSSCG00000008629
LinkDB
All DBs
Position
3:125353063..125493368
Genome browser
AA seq
1475 aa
AA seq
DB search
MSRPPPTGKMPGAPEAVSGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSPSCKENDSIQIRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCKSVNTRLEKV
AKELEEEIALRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETAKLKLEKDFINLQSVLESERRDRTHGSEIINDLQGRISGLEEDLKNGKI
LLTKVEMEKRQLQERFTDLEKEKNNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSILDCDLKQSQQKINELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDTTIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDMRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEADDGFPVHITQSHTMESMSFTYQRSSTSLNIATKPSSSHMLLDSDSDSEEESVPYLP
ISSEPNGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLD
IDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNCICHKGH
EFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDI
SSAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQ
LAANKPRLLDLAFKDWDWSFDDIDGGDDDGDVFDF
NT seq
4428 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccgccgacggggaaaatgcccggcgcccccgaggccgtgtcgggggac
ggcgcgggcgcgagtcgccagaggaaactggaggcgctgatccgagaccctcgctcgccc
atcaacgtggagagcttgctggatggcttaaattccttggtcctcgatttggattttcct
gctttgaggaaaaacaagaatatagacaatttcttaaatagatatgagaaaattgtaaaa
aagatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtgcagttggttcgtcataaggcatcacagaaggtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatcagattctgcttttttctgggaggaa
agagatattatggcctttgccaacagtccctgggtggttcagcttttttgtgcctttcaa
gatgataagtatctatacatggtaatggagtacatgcctggtggagaccttgtgaacctc
atgagtaactacgatgtacctgaaaaatgggccaagttttatactgccgaagttgttctt
gctttggatgccatacactccatgggtttaattcacagagatgtgaagcctgacaacatg
cttttggataaacatggacatctaaaattagcagattttggcacatgtatgaagatggat
gaaacaggcatggtgcattgtgatacggcagttggaacacctgactatatatcacctgag
gttttgaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgtg
ggtgttttcctttttgagatgctggtgggggatactccattttatgcagattcacttgta
ggaacatacagcaaaattatggatcataaaaactcgttatgtttccctgaagatgcagaa
atttctaaacatgcgaagaatctcatctgtgccttcttaacagatagggaggtgcgactt
gggagaaatggggtggaagaaatcaaacaacatcctttctttaagaatgatcagtggaat
tgggataacataagagagacggcagctcctgtggtacctgagctcagcagtgacatagac
agcagcaattttgacgacattgaggatgataaaggagatgtggaaaccttcccaattcct
aaagctttcgtgggaaatcagctgccctttatagggtttacctattatagagaaaatctg
ttattaagtgactctccatcttgtaaagaaaatgattcaatacaaataaggaagaatgaa
gaaagtcaagagattcagaaaaagctatacacattagaagaacaccttagcactgagata
caagccaaagaggaactagagcagaagtgcaagtctgttaatactcgcctggagaaagta
gcaaaggagctagaagaagagattgccttaaggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcacttcttcagcacaaaaatgcagaatatcagcggaaggctgat
catgaagcagacaagaaacgaaatttggagaatgatgttaacagcttaaaagatcaactg
gaagatttgaaaaaaagaaatcagaactctcagatatccactgagaaagtgaatcaactc
cagagacagctggatgaaaccaatgctttgctgcgaacagaatctgatactgcggcccgg
ttaagaaaaacccaggcagaaagttcaaaacagattcagcagctggaatctaacaataga
gatctacaagataaaaattgcctgctggaaactgccaagttaaaacttgaaaaggatttt
atcaatctgcagtcagttctagaatctgaaaggagggaccgaacccatggatcagagatt
attaatgatttacaaggtagaatatctggcctggaagaagatttaaagaatggcaaaatc
ttattaaccaaagtagagatggagaagagacaactacaggagagatttactgatttggaa
aaggagaagaataacatggaaatagatatgacataccaactgaaagttatacagcagagc
ttagaacaggaagaggctgaacataaggctacaaaagcacggcttgcagataaaaataaa
atttatgaatccattgaagaagctaaatcagaagccatgaaagaaatggaaaaaaagctc
ttggaggaaagaactttaaaacagaaagtagagaacttgttgctggaagctgagaaaaga
tgctccatattagactgtgacctcaaacagtcacagcagaaaatcaatgaactcctcaaa
cagaaagatgtgctaaatgaggatgttagaaacttaacattaaaaatagagcaggaaact
cagaagcgctgccttacgcaaaatgacttgaagatgcaaacacagcaagttaacacgcta
aaaatgtcagaaaagcagttaaaacaagagaacaatcatctcatggaaatgaaaatgagc
ttggaaaaacagaatgctgaacttcgaaaagaacgtcaagatgcggatgggcaaatgaaa
gagctccaagatcagctggaagcagagcagtacttctcaaccctctataaaacacaggtt
agagaactgaaagaagaatgtgaagagaagaccaagctttgtaaggaattacagcagaag
aaacaggaactgcaggatgaaagagactccttggctgctcaactggagattaccttgacc
aaagcagattctgagcagctggctcgttcaattgccgaagaacaatattctgacttggaa
aaagagaagatcatgaaagagctggagatcaaagagatgatggccagacacaagcaggaa
ctcacggaaaaagatactacaatcgcatcccttgaagaaacgaataggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaattgaaagatgcccaa
gagcaactatcaagattgaaagatgaagagataagtgcagcagctattaaagcgcagttt
gagaagcagctgttaacagagagaacactcaaaactcaagctgtgaataagttggctgag
atcatgaatcggaaagaacctgttaagcgtggtaatgacacagatatgcggagaaaagaa
aaggagaatagaaagctacatatggaacttaaatctgaacgtgaaaaactgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggctcaaattgctgaagagagtcag
attcgaattgaactgcagatgacactggacagtaaagacagtgacattgagcagctgcga
tcccagctccaggccttgcatattggtctggatagttccagcataggcagcggaccaggg
gatgctgaagcagatgatgggtttccagttcatatcactcagtcacacactatggaatcc
atgtcattcacctaccaacgttcctctacttctctcaatattgccactaagccttccagt
tctcatatgcttcttgactctgattctgactcagaagaagaatctgtgccttacttacct
atttcgtcggaacctaatggtacagaatcaagattagaaggatggctttcattgcctgtg
cgaaacaacactaagaaatttggatgggttaaaaagtacgtgattgtaagcagtaagaag
atccttttttatgacagtgaacaagataaagaacaatctaacccgtacatggttttagat
atagacaagttatttcatgttcgaccagttacacagacagatgtatatagagcagatgct
aaagaaattccaaggatattccagattctctatgccaatgaaggagaaagtaagaaggaa
caagaatttcccgtagagccggtgggagaaaaatcaaattgtatttgccacaagggacat
gaatttattcccactctctaccatttcccaaccaactgtgaggcctgtatgaagccgttg
tggcacatgtttaaacctcctcctgctttggagtgccgtcgctgccatattaaatgtcat
aaagatcacatggataaaaaggaggaaattatagcaccctgcaaagtgtactatgacatt
tcatcggcaaagaatctattattattagcaaattctacagaagagcagcaaaagtgggtt
agtcggttagtgaaaaagatacctaagaagcctccagctccagacccttttgcacggtca
tctcctaggacatcaatgaaaatacaacaaaaccagtctatcagacggccaagtcgacag
cttgccgcaaacaaaccaagattgcttgatttggcatttaaagactgggattggtcgttt
gatgatattgatggtggtgatgatgatggcgatgtttttgatttctga
DBGET
integrated database retrieval system
