Scomber scombrus (Atlantic mackerel): 133993012
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Entry
133993012 CDS
T10651
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ssco Scomber scombrus (Atlantic mackerel)
Pathway
ssco00140
Steroid hormone biosynthesis
ssco01100
Metabolic pathways
Module
ssco_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
ssco_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
ssco_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ssco00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
133993012 (hsd3b1)
Enzymes [BR:
ssco01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
133993012 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
133993012 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
NmrA
RmlD_sub_bind
KR
adh_short
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
133993012
NCBI-ProteinID:
XP_062287820
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Position
13:2778310..2780428
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AA seq
376 aa
AA seq
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MSLRGDVCVVTGASGFLGKRLVRLLLEEENIAEVRLLDKRVPPQLVQTLEDCRGDTKVSV
FEGDIRDGDFLQKACRGASIVFHIASIIDLNGSVEDSEMYGVNVKGTQLLLEACIQENVV
SFIYTSTIEVMGPNAKGEPIINGNEDTFYNSSLKFAYSKTKKEAEQRTLRAHGEMLKNGG
RLATCALRPMYIFGEGCRFLLGHMGDGIRNKDKLFRMSLPEARVNPVYVGNVAVAHIQAA
RSLKDPPKRNAIGGKFYFISDDTPPVSYSDFNHVVMSPLGFRIQDKLPLPLGLFYMFCFF
MEIVCAILRPLIRIAPPLNRQLLTMLNTPFTFSYQKAKRDLGYIPRYTWEEARKSTMEWL
ASQLPQERERKNNIKK
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggggatgtgtgtgtggtgactggagcctctggattcctggggaaaaga
ctggtccggctgctgctggaggaagagaacattgctgaggttcgactgctggacaaacgc
gtaccaccccaactcgtacagactctggaggactgtagaggtgacacaaaggtgagtgtt
ttcgagggggacatcagggacggagatttcctacaaaaagcctgccgtggtgcatcgatc
gtcttccacatcgcatccatcattgaccttaatggatcagtggaggacagcgagatgtat
ggggtcaatgtcaaaggaacacagctgctcctagaagcatgtattcaagagaacgtggtg
tccttcatctacaccagcaccattgaggtaatgggcccgaatgccaaaggtgaacctata
atcaacggcaatgaggacacattttacaactcctccctgaagtttgcctacagcaaaact
aaaaaggaggctgagcagagaaccctccgggcccacggcgagatgctcaaaaacggaggc
cgactggccacctgcgccctcagacccatgtacatctttggagagggttgtcgcttcctc
ctgggccacatgggcgatgggatacgaaacaaggataagctgttccgaatgtctttacca
gaagcccgtgtgaatcctgtctatgtgggtaacgtggctgtggctcacatccaggcagct
cgcagcctcaaagatccaccaaaaagaaatgcgatcggaggaaagttttacttcatttca
gatgatacaccgcccgtgagttattcagacttcaaccacgtcgtgatgtcacccctgggc
ttccgcattcaagataaactcccgctgccgcttggcctcttctacatgttctgcttcttt
atggagattgtgtgcgcgattctccgccctttgatacgcatcgcaccacctctgaaccgg
cagctcctcaccatgttgaacacaccgttcaccttctcctatcaaaaggctaagagggac
ctgggatacatccccagatacacctgggaggaagcacgcaaaagcaccatggaatggctt
gcctcccagttgccacaggagagggaaagaaaaaataatattaaaaaatga
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