KEGG   Staphylococcus pseudintermedius HKU10-03: SPSINT_2038
Entry
SPSINT_2038       CDS       T01396                                 
Name
(GenBank) Dihydrofolate reductase
  KO
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
ssd  Staphylococcus pseudintermedius HKU10-03
Pathway
ssd00670  One carbon pool by folate
ssd00790  Folate biosynthesis
ssd01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ssd00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SPSINT_2038
   00670 One carbon pool by folate
    SPSINT_2038
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:ssd01504]
    SPSINT_2038
Enzymes [BR:ssd01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SPSINT_2038
Antimicrobial resistance genes [BR:ssd01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    SPSINT_2038
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ADV06566
LinkDB
Position
2110300..2110797
AA seq 165 aa
MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILGRKNLESIGRALPDRRN
IILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIYNLFFPYVEKMYITKIHHE
FEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYERKNLLS
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaaagtttctttgattgctgcgatggataagaatagagtgattggcaaagagaatgac
attccttggaggattcccaaggactgggaatatgttaaaaatactacaaagggacatccg
ataatattaggtaggaagaaccttgaatcaatcggaagagccttacctgacagaagaaat
attattctgacgagagataaggggtttacctttaatggttgtgaaattgttcattcaata
gaagatgtttttgagttatgtaaaaacgaagaagaaatttttattttcggaggagaacag
atttataatttgtttttcccttatgttgagaaaatgtacatcacaaaaatacatcatgaa
ttcgaaggagatactttttttccagaagtgaattatgaggaatggaatgaggtatttgcc
caaaaagggataaagaatgataaaaatccgtataactactattttcatgtatatgaaaga
aaaaacttattgagttaa

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