KEGG   Streptomyces solicathayae: R2D22_11235
Entry
R2D22_11235       CDS       T11073                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ssli  Streptomyces solicathayae
Pathway
ssli03030  DNA replication
ssli03410  Base excision repair
ssli03420  Nucleotide excision repair
ssli03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ssli00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    R2D22_11235 (ligA)
   03410 Base excision repair
    R2D22_11235 (ligA)
   03420 Nucleotide excision repair
    R2D22_11235 (ligA)
   03430 Mismatch repair
    R2D22_11235 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ssli03032]
    R2D22_11235 (ligA)
   03400 DNA repair and recombination proteins [BR:ssli03400]
    R2D22_11235 (ligA)
Enzymes [BR:ssli01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     R2D22_11235 (ligA)
DNA replication proteins [BR:ssli03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     R2D22_11235 (ligA)
DNA repair and recombination proteins [BR:ssli03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     R2D22_11235 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     R2D22_11235 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     R2D22_11235 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      R2D22_11235 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_5 HHH
Other DBs
NCBI-ProteinID: WOX21935
LinkDB
Position
complement(2512200..2514386)
AA seq 728 aa
MAVEQGALPADVREQHAQLAEQVEEHRFRYYVKDQPVVSDAEFDRLLRALEALEDEYPAL
RTPDSPTQKVSGDYETGLAKVDHRERMLSLDNAFDDAELAAWAERVARDVGASGYHFLCE
LKVDGLAVNLTYEKGRLTRAATRGNGTTGEDITPNARTIQGIPDRLKGDRIPDLVEIRGE
VYFPMEKFEELNARRIAAGEQPYANPRNSASGSLRQKDPRVTATLPLRMVVHGLGARDGL
DIARLSEAYELLHEWGLPTARHNRVVDSLAGVREFIAYFGENRHSVEHEIDGVVVKLDEI
PLQGRLGSTARAPRWAIAWKYPPEEVNTKLVDIKVGVGRTGRVTPYAQVEPVTVAGSEVE
FATLHNQDVVKLKGVLIGDTVVLRKAGDVIPEILGPVVDLRDGTEREFVMPAECPECGTP
LRAMKEGDIDLRCPNARTCPAQLRERVSYLAGRECLDIENFGEVAAAALTRPLEPAEPAL
RDEGDLFDLTIEQLLPIKAYVRDQDSGLPKRDPKTGEAKVVTVFANQKGEPKKNALAMLA
NIEAAKQRPLARFLNGLSIRHVGPVAAQALAREFRSIDRIDAATEQELAATEGVGPIIAA
AVKQWFAEDWHREILRKWREAGARTEDEGAGEDEGPRPLEGLTVVVTGTLENHTRDGAKE
ALQSRGAKVTGSVSKKTDFVVVGDNPGSKYDKAMQLKVPVLNEEGFAVLLEQGPEAAREA
AVPVPEAG
NT seq 2187 nt   +upstreamnt  +downstreamnt
gtggctgtcgaacagggggccctgcccgccgacgtgcgggagcagcacgcacagctggcc
gagcaggtcgaggagcaccgcttccggtactacgtgaaggaccagccggtcgtcagtgac
gcggagttcgacaggctcctgcgcgccctcgaggcgctggaggacgagtacccggcgctg
cgcacgcccgactcgccgacccagaaggtctccggggactacgagacgggcctcgcgaag
gtcgaccaccgggagcggatgctctcgctcgacaacgccttcgacgacgcggagctcgcc
gcctgggcggagcgcgtcgcgcgggacgtcggcgcgtccgggtaccacttcctgtgcgag
ctgaaggtcgacggcctggcggtcaacctcacgtacgagaagggccggctgacccgggcc
gccacccggggcaacggcaccacgggcgaggacatcacgcccaacgcccggacgatccag
ggcattccggaccgactcaagggcgaccggatcccggacctcgtggagatccgcggcgag
gtctacttcccgatggagaagttcgaggagctgaacgcccgccggatcgccgccggcgag
cagccgtacgccaacccgcgcaactccgcctcgggttcgctgcgccagaaggacccccgg
gtcaccgccacgctgccgctgcgcatggtcgtgcacggcctcggtgcccgcgacggcctg
gacatcgcccggctctccgaggcgtacgagctgctccacgagtggggcctgccgaccgcc
cggcacaaccgggtggtcgactcgctggcgggcgtgcgcgagttcatcgcgtacttcggc
gagaaccggcactccgtcgagcacgagatcgacggcgtggtcgtgaagctggacgagatc
ccgctccagggtcggctgggctcgacggcgcgcgcgccgcgctgggcgatcgcctggaag
tacccgccggaggaggtcaacaccaagctggtcgacatcaaggtcggcgtcggccggacc
ggccgggtcacgccgtacgcgcaggtcgagccggtcacggtggccgggtccgaggtcgag
ttcgccaccctgcacaaccaggacgtggtgaagctcaagggcgtgctgatcggcgacacg
gtggtgctgcgcaaggcgggcgacgtgatcccggagatcctcggcccggtcgtcgacctg
cgggacggcacggagcgcgagttcgtcatgccggccgagtgtcccgagtgcggtacgccg
ctgcgggccatgaaggagggcgacatcgacctgcgctgcccgaacgcccggacctgcccg
gcccagcttcgggagcgcgtctcctacctcgccggccgcgagtgcctggacatcgagaac
ttcggcgaggtggcggcggcggcgctgacccgcccgctggagccggccgagccggcgctg
cgcgacgagggcgacctgttcgacctgacgatcgagcagctgctgccgatcaaggcgtac
gtgcgcgaccaggacagcgggctgcccaagcgggacccgaagaccggcgaggcgaaggtc
gtcacggtcttcgccaaccagaagggcgagccgaagaagaacgcgctggcgatgctggcg
aacatcgaggccgccaagcagcgtccgctcgcccgcttcctcaacggcctgtcgatccgg
cacgtgggtccggtcgcggcccaggcgctggcccgcgagttccgctccatcgaccgcatc
gacgcggccaccgagcaggagctggcggccaccgagggcgtcggcccgatcatcgcggcc
gcggtgaagcagtggttcgccgaggactggcaccgcgagatcctgcgcaagtggcgggag
gccggggcccggacggaggacgagggggccggcgaggacgagggcccgcgtccgctggag
gggctgacggtcgtcgtcaccggcaccctggagaaccacaccagggatggcgcaaaagag
gcgttgcagagccgcggagcgaaggtgaccggttccgtttcgaagaagaccgactttgtc
gttgtgggtgacaacccggggtccaaatacgacaaggcgatgcagctgaaggttccggtt
ctgaacgaggaaggcttcgcggtgctgctggaacagggtccggaggccgcccgggaggcc
gcggtcccggtgcccgaggccggctga

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