Streptomyces solicathayae: R2D22_12165
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Entry
R2D22_12165 CDS
T11073
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ssli Streptomyces solicathayae
Pathway
ssli00020
Citrate cycle (TCA cycle)
ssli00630
Glyoxylate and dicarboxylate metabolism
ssli00785
Lipoic acid metabolism
ssli01100
Metabolic pathways
ssli01110
Biosynthesis of secondary metabolites
ssli01120
Microbial metabolism in diverse environments
ssli01200
Carbon metabolism
ssli01210
2-Oxocarboxylic acid metabolism
Module
ssli_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ssli_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ssli00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
R2D22_12165
00630 Glyoxylate and dicarboxylate metabolism
R2D22_12165
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2D22_12165
Enzymes [BR:
ssli01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
R2D22_12165
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
R2D22_12165
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
R2D22_12165
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
R2D22_12165
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WOX22105
UniProt:
A0ABZ0LRJ1
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All DBs
Position
2718107..2721910
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AA seq
1267 aa
AA seq
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MSSQSPSTPSTSTDQDGQGQNPATAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GSTEAPAAAPQVSPAQAAPAAPAAPAAPAAPAQAAPTPAAAPAASAPAAPAPAPAPAPAK
PAAAAPAAVKAAPAPAKAAPAAEAPAGPELVTLRGPAAAVAKNMNLSLEMPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPD
HVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVKRARVGKLTMEDFTGVT
VSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTY
DHRVIQGAASGEFLRIVANLLLGEDGFYDDIFKALRIPYEPVRWLKDIDASHDDDVTKAA
RVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMK
LRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRVERSHSKPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPV
LEGVVRAKQDVINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVI
NNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVV
IDLICYRRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDF
QGQLEKVFAEVREATSAPAPVHVPDTRAEFPVAVSTAVSQEVVKRIAESQVNVPERITVH
PRLMPQMQRRAASVEDGTIDWGMGETLAIGSLLMEGTTVRLAGQDSRRGTFGQRHAVLVD
QETGEDYTPLLYLADDQARYNVYDSLLSEYAAMGFEYGYSLARPDALVIWEAQFGDFVNG
AQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPT
LPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTTGGFRPVIGDDSVNPAD
VRKVVFCAGKVYYDLEAERQKRGNTDTAIIRVERLYPLPGAELQAEIAKYPNAAKYIWAQ
EEPANQGAWPFIALNLIDHLDLAVGADLPPAERLRRISRPHSSSPAVGSAKRHQAEQQQL
CNEVFEA
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaccccgagtacctccaccgaccaagacgggcagggtcag
aaccctgctaccgccttcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgatcgtgcctggtgggacttcttcgccgactacaagccc
ggctcgacggaggctcccgccgccgcgccgcaggtgagccccgcacaggctgcacctgcc
gctccggccgcccccgccgctccggccgcgcccgcccaggccgccccgaccccggccgcc
gctccggctgcgtccgctccggccgctccggctccggctccggctccggctccggcgaag
cccgccgcggccgcgccggccgccgtcaaggccgctccggcgcccgccaaggccgctccg
gcggccgaggccccggccggtcccgagctggtcacgctgcgcggtcccgccgccgccgtc
gcgaagaacatgaacctctcgctggagatgccgacggccacgtccgtccgcgccgtcccg
gtgaagctgctcttcgacaaccggatcgtgatcaacaaccacctgaagcgcgcccggggc
gggaagatctccttcacccacctcatcggctacgcgatggtgcaggcgatcaaggccatg
ccgtcgatgaactactccttcgcggagaaggacggcaagccgacgctggtcaagccggac
cacgtgaacttcggtctggccatcgacctggtgaagccgaacggcgaccgccagctcgtc
gtcgcgggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgag
gacatcgtcaagcgcgcccgcgtcggcaagctgacgatggaggacttcaccggcgtcacg
gtctcgctgaccaaccccggcggcctcggcacggtccactccgtgccgcgtctgatgccc
ggacagtcggtcatcatgggcgtcggctcgatggactacccggccgagttccagggcacg
agccaggacaccctcaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctac
gaccaccgggtgatccagggcgccgcctccggcgagttcctgcgcatcgtcgcgaacctg
ctcctcggcgaggacggcttctacgacgacatcttcaaggccctgcgcatcccctacgag
ccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcg
cgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgac
ccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctcacc
ctgtgggacctggagcgcgagttcgcggtcggcggcttcgccggcaagtcgatgatgaag
ctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcgtcgagttc
atgcacatccaggacccgaagcagcgcaagtggatccaggaccgcgtcgagcgctcgcac
tccaagccggagcgcgaggagcagctgcggatcctgcgccgtctgaacgccgcggaggcg
ttcgagaccttcctgcagaccaagtacgtcggtcagaagcgcttctcgctggagggcggc
gagtccgtcatcccgctgctcgacgcggtcatcgactcggccgccgagtcgcgcctggac
gaggtcgtcatcggcatggcccaccgcggccggctgaacgtcctcgccaacatcgtcggc
aagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggc
gagcagatcaaggtctcgctggtcgccaacccctcgcacctggaggcggtcgacccggtc
ctggagggtgtcgtccgcgccaagcaggacgtcatcaacaagggcggcacggacttcacc
gtcctgccggtcgccctgcacggcgacgcggccttcgcgggccagggcgtcgtggccgag
acgctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatc
aacaaccaggtcggcttcaccgccgccccggagtcctcgcgttcctcgatgtacgcgacc
gacgtggcccgcatgatcgaggcgccgatcttccacgtgaacggcgacgacccggaggcc
gtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttcaacaaggacgtcgtc
atcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccgcagttcacc
aacccgcagatgtacaacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgag
tcgctcatcggtcgcggcgacatcaccctcgaagaggcggagcaggcgctccaggacttc
cagggccagctggagaaggtcttcgcggaggtccgcgaggccacctcggcgccggccccg
gtgcacgtccctgacacccgcgccgagttcccggtcgccgtgagcaccgcggtctcccag
gaggtcgtgaagcggatcgccgagtcgcaggtgaacgtccccgagcggatcaccgtccac
ccgcgcctgatgccgcagatgcagcgccgcgcggcctcggtcgaggacggcacgatcgac
tggggcatgggcgagaccctggccatcggttcgctgctgatggagggcaccacggtccgg
ctcgccggccaggactcccgccgcggcaccttcggccagcgccacgcggtcctggtcgac
caggagaccggcgaggactacaccccgctgctctacctggccgacgaccaggcccggtac
aacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcg
ctggcccgcccggacgcgctggtcatctgggaggcccagttcggtgacttcgtcaacggc
gcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggccagacctcc
ggcgtcacgctgctgctgccgcacggctacgagggccagggcccggaccactcgtccgcc
cgcccggagcgcttcctccagatgtgcgcgcaggacaacatgacggtcgcgatgccgacc
ctgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccg
ctgatcgtcttcaccccgaagtcgatgctgcgcctgaaggccgcggcctcgaaggcggag
gagttcaccaccggcggcttccgcccggtgatcggcgacgactcggtgaacccggccgac
gtccgcaaggtcgtcttctgcgccggcaaggtctactacgacctggaggccgagcggcag
aagcgcggcaacacggacaccgcgatcatccgcgtggagcgcctgtacccgctgccgggt
gccgagctccaggccgagatcgccaagtacccgaacgccgcgaagtacatctgggcgcag
gaggagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctgatcgaccacctg
gacctggcggtcggcgcggacctgcccccggcggagcggctgcggcgcatctcgcgcccg
cactcctcctcgccggcggtcggctcggccaagcgtcaccaggcggagcagcagcagctg
tgcaacgaggtcttcgaggcgtag
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