Solea solea (common sole): 131475547
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Entry
131475547 CDS
T10853
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ssoe Solea solea (common sole)
Pathway
ssoe00140
Steroid hormone biosynthesis
ssoe01100
Metabolic pathways
Module
ssoe_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
ssoe_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
ssoe_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ssoe00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
131475547 (hsd3b1)
Enzymes [BR:
ssoe01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
131475547 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
131475547 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
KR
NmrA
adh_short
Motif
Other DBs
NCBI-GeneID:
131475547
NCBI-ProteinID:
XP_058509740
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Position
2:36964093..36967573
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AA seq
373 aa
AA seq
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MSLRGDVCVVTGACGFLGKRLVQLLLEEEKMAEIRLLDKHVQPQVLLTLEDCRGSTKLSV
FEGDIRDAEFVRKVCRGASLVFHTASIIDVNDSVEYREIHGVNVKGTQVLLEACIQENVV
SFIYTSTIEVMGPNPRGEPIVNGNEDTIYNCTLKFTYSKTKKEAEQCTLHAHGEVLQNGG
RLATCALRPMYIFGEGCRFLLGHMGDGIRNKDVLLRMSRRDALVNPVYVGNVAAAHLQAA
RGLKDPQKRNLIGGKFYFIADDTPPVSYSDFNHAVMSPLGFGIQEKLMLPLRLLYVVCFF
VEILCALLRPVVRVVPPLNRQLLTMLNTPFTFSYQRAEKDLGYKPRYSWEEARLHTVEWL
ASELPKERGRIRG
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggcgacgtgtgtgtggtgacgggagcgtgtggattcctggggaagagg
ctggtgcagctgctgctggaggaagagaagatggccgagattcggctgctggacaaacat
gtgcagccgcaggttttactcacactggaggactgcagaggcagcacaaagctgagcgtg
ttcgagggcgacatcagagacgctgagtttgtgagaaaagtctgtcgaggcgcgtcgctc
gtcttccacaccgcgtccatcatcgacgtgaacgactcggtggagtacagagaaattcac
ggggtcaacgtcaaaggaacccaggttcttctggaggcgtgcatccaggagaacgtggtg
tccttcatctacaccagtaccatcgaggtgatgggccccaaccccagaggtgaacccatc
gtgaacggcaacgaggacacgatctataactgcactctgaagttcacctacagtaagacc
aagaaggaggcggagcagtgcacgctgcacgctcacggcgaggtgctacaaaatggaggc
cgactcgccacgtgtgccctcagacccatgtacatcttcggcgagggctgccgcttcctg
ctgggccacatgggcgacgggatacggaacaaggacgtcctgctgcgaatgtctcgccgc
gacgcgcttgtgaatcccgtctacgtgggcaacgtggcggcggctcacctccaagccgct
cgcggcctcaaagatccacaaaaacgaaacctcatcggagggaagttttacttcatcgcc
gacgacacaccgcccgtgagctactccgacttcaaccacgccgtgatgtcaccgctgggc
ttcggcattcaggagaaactcatgcttcccctccgcctcctctacgtcgtctgtttcttt
gtggagattctgtgcgcgctgctgcgacccgtcgtgcgagtcgtgccgccgttgaaccgg
cagcttctcaccatgttgaacacgccgttcaccttctcctaccagagagccgagaaggat
ctgggatacaagcccaggtacagctgggaggaggcacgcttacacaccgtggagtggctc
gcctccgagttaccaaaggagagggggcggataagaggttaa
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