Streptomyces malaysiensis HNM0141: I1A49_10780
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Entry
I1A49_10780 CDS
T07406
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ssoi
Streptomyces malaysiensis HNM0141
Pathway
ssoi00270
Cysteine and methionine metabolism
ssoi00450
Selenocompound metabolism
ssoi00670
One carbon pool by folate
ssoi01100
Metabolic pathways
ssoi01110
Biosynthesis of secondary metabolites
ssoi01230
Biosynthesis of amino acids
ssoi04980
Cobalamin transport and metabolism
ssoi04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ssoi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
I1A49_10780 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
I1A49_10780 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
I1A49_10780 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
I1A49_10780 (metH)
04980 Cobalamin transport and metabolism
I1A49_10780 (metH)
Enzymes [BR:
ssoi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
I1A49_10780 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
QPI55344
LinkDB
All DBs
Position
complement(2816214..2819720)
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AA seq
1168 aa
AA seq
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MASYTPSPTSAARADALREALATRVVVADGAMGTMLQAQDPSLDDFQQLEGCNEILNVTR
PDIVRSVHEAYYAVGVDCVETNTFGANHAALGEYDIPDRVHELSEAGARIAREVADEFGA
DGRQRWVLGSMGPGTKLPTLGHAPYTILRDAYQANAEGMIAGGADALLVETTQDLLQTKA
AIIGARRALDATGANLPVICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGPT
EMSEHLRHLARHSRIPLSCMPNAGLPVLGKDGAHYPLTPGELADAQETFVREYGLSLVGG
CCGTTPEHLRQVVERVRELTPTERSPRPEPGAASLYQTVPFRQDTSYLAIGERTNANGSK
KFREAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMEELAGRFATASTLPIV
LDSTEVDVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTQLAREHGAALIALTIDEEG
QARTPEHKVEIAERLIADLTGNWGIREDDILIDCLTFTICTGQEESREDGIATIEAIREL
KRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIARFEDE
EVETALDLIYDRRAEGYDPLQKLMGLFEGATAKSLKAGKAEELAALPLEERLKRRIIDGE
RNGLEADLDEALQERPALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAHL
EPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEAAE
EHRADVIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEIYEG
EVRYARDAFEGLRLMDALIAVKRGVPGATLPELRQRRVPQRAAQVREPEPDQGPARSDVA
TDNPVPTPPFWGTRVVKGIQQADYASWLDEGALFKGQWGLKQSRTGDGPGYEELVEREGR
PRLRGWLDRLHTGNLLEAAVVYGYFPCVSKGDDLVLLNEDGSERTRFTFPRQRRGRRLCL
ADFFRPEESGETDVVGLQVVTVGSKIGEMTAELFAADSYRDYLELHGLSVQLAEALAEYW
HARVRAELGFAGEDPGEMEDMFALKYRGARFSLGYGACPDLEDRAKIADLLGPERIGVKL
SEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3507 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgtacacgccatcgcccacatccgccgcccgagccgacgcgcttcgtgaagcg
ctggccacccgcgtggtggtcgccgacggcgcgatggggacgatgctccaggctcaggac
cccagtctcgacgacttccagcagctcgaaggctgcaacgagatcctcaacgtcacccgc
ccggacatcgtccgctcggtccacgaggcgtactacgccgtcggtgtggactgtgtcgag
accaacaccttcggcgccaaccacgcggcgctcggcgagtacgacatccccgaccgcgtc
catgagctctccgaggccggcgcccggatcgcccgtgaggtcgccgacgagttcggcgcc
gacggacgccagcgctgggtgctcggctcgatgggccccggcaccaagctgcccaccctc
ggccacgcgccctacaccatcctccgcgacgcctaccaggccaacgccgagggcatgatc
gccggcggcgcggacgccctcctggtggagaccacccaggacctgctccagaccaaggcc
gcgatcatcggcgcccgccgcgccctggacgccaccggtgccaacctccccgtgatctgc
tcggtcactgtcgagaccaccggcaccatgctgctcggctccgagatcggcgcggcgctc
accgccctcgagccgctcggcatcgacatgatcggcctcaactgcgccaccggccccacc
gagatgagcgagcacctgcgccatctcgcccgccactcccgtatcccgctgtcctgcatg
cccaacgccggccttccggtgctgggcaaggacggcgcccactaccccctcactcccggc
gaactggccgacgcccaggagaccttcgtccgcgagtacgggctctccctggtcggcggc
tgctgcgggaccacccccgaacatctgcgccaggtcgtcgagcgggtccgcgagctgacc
cccaccgagcgctccccgcgccccgagcccggcgccgcctcgctctaccagaccgtgccg
ttccgccaggacacctcgtatctggcgatcggcgagcgcaccaacgccaacggctccaag
aagttccgcgaggccatgctggagggccgctgggacgactgcgtggagatggcccgggag
cagatccgcgagggcgcccatctgctcgacctgtgcgtggactacgtcggccgggacggc
gtggcggacatggaggagctggccgggcggttcgccaccgcctccaccctccccatcgtc
ctggactccaccgaggtcgacgtcatccgggccgggctggagaagctcggcggacgcgcg
gtcatcaactccgtcaactacgaggacggggacggccccgagtcgcggttcgccaaggtc
acccagctcgcgcgggagcacggcgccgccctgatcgcgctgaccatcgacgaggagggc
caggcccgcaccccggagcacaaggtggagatcgccgagcggctgatcgccgatctgacc
ggcaactggggcatccgcgaggacgacatcctcatcgactgtctgaccttcaccatctgc
accggtcaggaggagtcccgcgaggacggcatcgccaccatcgaggcgatccgcgagctc
aagcggcgccacccggacgtccagaccaccctcggcctgtcgaacatctccttcggcctc
aacccggccgcccgcatcgtgctcaactccgtcttcctcgacgaatgcgtcaaggcgggc
ctggactcggcgatcgtgcacgcctccaagatcctgccgatcgcgcggttcgaggacgag
gaggtcgagacggccctggacctgatctacgaccgccgcgccgagggctacgaccccttg
cagaagctgatggggctcttcgagggcgccaccgccaagtccctcaaggcgggcaaggcc
gaggagctggccgcgctgcccctggaggagcgcctcaagcggcgcatcatcgacggtgag
cgcaacggcctggaggccgacctcgacgaggccctccaggagcgccccgccctcgacatc
gtcaacgagacgctgctggacggcatgaaggtggtcggcgagctgttcggctccggccag
atgcagctgccgttcgtcctccagtccgccgaggtcatgaagacggccgtggcgcatctg
gagccgcacatggagaagtcggacgacgagggcaagggcaccatcgtgctggccaccgtc
cgcggcgacgtccatgacatcggtaagaacctcgtggacatcatcctgtccaacaacggc
tacaacgtggtcaacctcggcatcaagcagccggtctccgcgatcctggaggccgccgag
gagcaccgggccgatgtgatcggcatgtccgggctgctggtgaagtccacggtgatcatg
aaggagaacctggaggagctcaaccagcgcaagctggccgccgactaccccgtcatcctc
ggcggcgccgccctcacccgggcctatgtcgaacaggatctgcacgagatctacgagggc
gaggtgcgctacgcccgcgacgccttcgaggggctgcggctcatggacgccctgatcgcc
gtcaagcgcggggtgcccggcgccacgctccccgagctccggcagcgccgggtcccccag
cgcgccgcccaggtgcgggaaccggagccggaccagggcccggcgcgctccgacgtggcc
accgacaaccccgtacccaccccgccgttctggggcacccgcgtcgtcaagggcatccag
caggccgactacgcctcctggctggacgagggggcgctcttcaagggccagtgggggctc
aagcagtcccgcaccggcgatggccccggctacgaggaactggtggagcgcgagggccgg
ccccggctgcgcggctggctggaccggctgcacaccgggaacctgctggaggcggccgtg
gtctacggctacttcccgtgcgtctccaagggcgacgacctggtcctgctgaacgaggac
ggcagcgagcgcacccgcttcaccttcccgcgccagcggcgcggccgccggctgtgcctg
gccgacttcttccggcccgaggagtccggggagaccgatgtcgtcgggctccaggtggtg
accgtcggctcgaagatcggcgagatgaccgcggagctgttcgccgccgactcctaccgc
gactatctggagctgcacggtctgtccgtccagctggcggaggcgctggccgagtactgg
cacgcccgggtccgcgccgagctgggcttcgccggtgaggacccgggcgagatggaggac
atgttcgcgctgaagtaccgcggcgcgcgcttctcgctgggctacggcgcctgccccgac
ctggaggaccgcgcgaagatcgccgatctgctggggcccgagcggatcggggtgaagctc
tcggaggagttccagctccaccccgagcagtccacggacgccatcgtgatccaccacccg
gaggcgaagtacttcaacgcgcggtag
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