Streptomyces spinosirectus: LXH13_11465
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Entry
LXH13_11465 CDS
T08958
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00010
Glycolysis / Gluconeogenesis
sspn00020
Citrate cycle (TCA cycle)
sspn00620
Pyruvate metabolism
sspn00785
Lipoic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01120
Microbial metabolism in diverse environments
sspn01200
Carbon metabolism
sspn01210
2-Oxocarboxylic acid metabolism
Module
sspn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LXH13_11465 (aceE)
00020 Citrate cycle (TCA cycle)
LXH13_11465 (aceE)
00620 Pyruvate metabolism
LXH13_11465 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LXH13_11465 (aceE)
Enzymes [BR:
sspn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LXH13_11465 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
UIR17614
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Position
2475130..2477841
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AA seq
903 aa
AA seq
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MTDPHAIQPSELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTAAEPSVPGDEEMERRITAWNRWNAAAMVTRGAKHGVGGHIATFASA
AWLYETGFNHFFHGKESQESPGSGDQLYIQGHASPGIYARAFLDGRLTEAHLDNFRQEAG
GGGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGVKDVSSSHVWAFLGD
GEMDEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVI
KTLWGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALAEMAKL
LSDDKILECFHLSRGGHEARKVYAAYKAAVEFKGAPTVILAQTVKGHTLGEGFASKNANH
QMKKLTVDEFKAMRDRLELPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPAR
RTHALAPLPAPADKAFAAFDKGSGSQNVATTMAFVRLVKDLVRDKETGRRWVPIVPDEAR
TFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTA
YATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGH
SPVIAATNPAALSYDPAFAYEIAVIVKDGLRRMYGEAAPGEDPNVFYYLTVYNEPMPQPA
KPSAPGVDEGIVKGLYRFNTAESAGLSPVANAPRIQLLGSGTAIHWTLQAQKLLAEEWGV
AADVWSATSWTELRRDAMEADAALLRGEERVPYVRQALHGAEGPVLAVSDYMRQVPDQIA
QWVEQDWSSLGADGFGLSDTRDAARRHFGVDAPSIVVAALAQLARRGEVKATAVKEARER
YGL
NT seq
2712 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccccacgccatccagccgagcgagctcgaccagctcccggaccgggacccc
gaggagaccgccgaatggcaggcctccctggacgcggtcgccaaggcggcgggcccgcac
cgtgccgcgtacctgatgcggcgcacgctggagcgggcggagggcaacggcatcgcgctg
cccaagctcctcgagaccgactacgtcaacaccatcccgaccgccgccgagccgagcgtg
cccggtgacgaggagatggagcgccggatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccggggcgccaagcacggcgtaggcggccacatcgccaccttcgcctccgcg
gcctggctctatgaaacgggcttcaaccacttcttccacggcaaggaatcccaggaatcg
cccggctccggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccgcctcaccgaggcgcacctcgacaacttccgccaggaggcgggc
ggcggcggcctgccgtcgtacccgcacccgcggcgcctgccctggctgtgggagttcccg
acggtgagcatgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctac
ctcaccgcccgcggcgtcaaggacgtgtcgtcctcgcacgtgtgggcgttcctcggcgac
ggcgagatggacgagccggagtcgacggccgccctcgcgctcgcctcccgcgagggcctg
gacaacctgaccttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgcg
aacttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtgatc
aagaccctgtggggcacggcctgggacgagctgttccagctggacaccacgggcgcgctg
gtacgccggctgcgcgaggtaccggacgcgcaggtgcagacgtaccagacgcgtgacgcg
gcctacatccgcgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctg
ctgagcgacgacaagatcctcgagtgcttccacctctcccgcggtggccacgaggcgcgc
aaggtctacgccgcctacaaggccgccgtcgagttcaagggcgcgccgaccgtgatcctg
gcccagacggtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccac
cagatgaagaagctgacggtggacgagttcaaggcgatgcgtgaccgcctcgaactgccc
atcaaggacagcgacttcgtggacggcgtggtcccctacggccacccgggcgccgactcc
cccgaggtccgctacctccaggagcgccgcgcggccctcggcggcccggctccggcccgc
cgcacgcacgcgctcgccccgctgcccgcccccgcggacaaggccttcgccgccttcgac
aagggctccggctcgcagaacgtggcgaccacgatggccttcgtccgcctggtcaaggac
ctggtccgggacaaggagaccggcaggcgctgggtgccgatcgtccccgacgaggcgcgc
accttcggcatggagagcctcttcccctcgctcgggatctactcccccaagggccagacg
tacgagccggtcgaccgcgaccagctcatgtactacaaggaggccaagaacggccagatc
ctcaacgaggggatcaccgaggccggttcgatggccgacttcatcgccgcgtccaccgcg
tacgcgacgcacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctgg
cagcgcacggccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctggtg
ggcgccaccgcgggccggacgacgctgaccggtgagggtctgcagcacgccgacggccac
tcgccggtgatcgccgcgaccaacccggcggcgctgtcgtacgaccccgcgttcgcctac
gagatcgcggtgatcgtcaaggacggtctgcgccgtatgtacggcgaggcggcgccgggc
gaggacccgaacgtcttctactacctcaccgtctacaacgagccgatgccgcagccggcg
aagccgtccgcgcccggcgtcgacgagggcatcgtcaagggcctgtaccgcttcaacacc
gctgagtcggcgggcctctccccggtcgcgaacgccccgcggatccagctgctcggctcc
ggtacggccatccactggaccctccaggcgcagaagctgctcgccgaggagtggggcgtg
gccgcggacgtctggtcggcgaccagctggaccgaactgcgccgcgacgcgatggaggcg
gatgccgcgctgctgcggggcgaggagcgggtgccgtacgtccggcaggcgctgcacggc
gccgaggggccggtgctcgcggtctccgactacatgcggcaggtgccggaccagatcgcc
cagtgggtcgagcaggactggtcctcgctcggcgccgacggcttcggcctctccgacacc
cgcgacgcggcccgccgccacttcggcgtcgacgccccgtccatcgtcgtggcagcgctg
gcccagctggcacggcgcggggaggtcaaggcgacggccgtcaaggaggcccgggagcgg
tacgggctgtga
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