Streptomyces spinosirectus: LXH13_12815
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Entry
LXH13_12815 CDS
T08958
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00010
Glycolysis / Gluconeogenesis
sspn00020
Citrate cycle (TCA cycle)
sspn00620
Pyruvate metabolism
sspn00785
Lipoic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01120
Microbial metabolism in diverse environments
sspn01200
Carbon metabolism
sspn01210
2-Oxocarboxylic acid metabolism
Module
sspn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LXH13_12815 (aceE)
00020 Citrate cycle (TCA cycle)
LXH13_12815 (aceE)
00620 Pyruvate metabolism
LXH13_12815 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LXH13_12815 (aceE)
Enzymes [BR:
sspn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LXH13_12815 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
UIR17864
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Position
2754745..2757492
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AA seq
915 aa
AA seq
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MASGSDRSPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDQRGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAYLLDRLSAEQLDGFRQ
EKSKSPNGLSSYPHPRSMPDFWEFPTVSMGLGPIGAIYQARMNRYMHARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGLLVNRMNTTPDGQFQTYATESGAYIREHFFGDDQRLR
AMVEGMTDHQILMLGRGGHDHRKIYAAYKAALEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHLPITDKELEDGAPPYYHPGRDSEEIQYMHDRRKGCGGYVP
TRVVRSKPLDLPDDKAYATVKKGSGQQSIATTMAFVRLLKDLMRDKEFGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
QSQLLASTNPACVAYDPAYSYEIAYIVQDGLRRMYGASEEHPHGEDVFFYLTVYNEPIRH
PAEPANVDVEGIVRGLHRIGEGTSGTIPAQVIASGVAVPWAVEAQKILAEDWNVKADVWS
ATSWNELRREAVEVERHNLLHPEEEQRVPYVTRKLSGAEGPVVAVSDWMRSVPDQIARWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELAREGKVDRSVLKQAIDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatcagatcgcagcccgatcatcattggcggccttccgagtcaggttcct
gacttcgaccccgaggagacccaggagtggctcgactccctggatgccgccgtcgatcag
cgcggccgtgagcgagcccgttatctgatgctgcggctcatcgagcgggcccgcgagaag
cgcgtggccgtgccggagatgcgcagcacggactacgtgaacacgatcgcgaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaaggtcctgaacgcgacccgctgg
aacgcggcggtgatggtctcgcgcgcccagcgccccggcatcggtgtcggcgggcacatc
gccaccttcgcctcctccgcgtcgctgtacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccaggggcatgcctcccccggtatc
tacgcacgcgcctacctgctcgaccggctcagcgccgagcagctcgacggcttccgccag
gagaagtccaagagccccaacggcctgtccagctacccgcacccgcgctccatgccggac
ttctgggagttcccgacggtctccatgggcctcggcccgatcggtgcgatctaccaggcg
cggatgaaccgctacatgcacgcgcgcgggatcgccgacacctcgaaatcgcatgtgtgg
gccttcctcggcgacggcgagatggacgagcccgagtcgctcggccagctgtccatcgcc
gcccgcgagggtttggacaacctgaccttcgtcgtcaactgcaacctgcagcgcctggac
gggccggtgcgcggcaacggcaagatcatccaggagctggagtcggtcttccgcggtgcc
ggctggaacgtcatcaagctgatctgggaccgctcctgggacccgctgctcgcccaggac
cgcgacgggctgctggtcaaccggatgaacaccacgccggacggccagttccagacgtac
gccaccgagtccggcgcgtacatccgcgagcacttcttcggtgacgaccagcggctgcgc
gccatggtcgagggcatgaccgaccaccagatcctgatgctgggccgcggcggtcacgac
caccgcaagatctacgcggcgtacaaggcggccctggagcacaagggccagccgacggtg
atcctggccaagacgatcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagggcttccgcgaccggctgcac
ctgccgatcaccgacaaggagctggaggacggggcgccgccgtactaccacccggggcgc
gactccgaggagatccagtacatgcacgaccgccgcaagggctgcggcggttacgtcccc
acgcgcgtggtgcgctccaagccgctcgacctgccggacgacaaggcgtacgcgaccgtg
aagaagggttccggtcagcagtcgatcgccacgaccatggcgttcgtgcggctgctcaag
gacctcatgcgggacaaggagttcggcaagcggttcgtgctgatcgcgccggacgagtac
cgcaccttcggcatggactcgttcttcccgagtgcgaagatctacaacccgctcggccag
cagtacgagtcggtggaccgtgaactcctgctcgcctacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcacggcctcgctgatcgcggcgggctcg
gcctacgccacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcgga
ttccagcgcaccggcgaccagttctggcagatggccgaccagctcgcgcgcggattcgtg
ctgggtgcgaccgccggccgtacgaccctgaccggtgagggtctgcagcacgcggacggc
cagtcccagctgctcgcctcgaccaacccggcctgcgtcgcctacgacccggcgtactcg
tacgagatcgcgtacatcgtccaggacgggctgcgccggatgtacggcgcctccgaggag
cacccgcacggcgaggacgtcttcttctacctcaccgtctacaacgagcccatccggcac
ccggccgagccggcgaacgtggacgtcgagggcatcgtcaggggcctgcaccggatcggg
gagggcacctcgggcacgatcccggcgcaggtcatcgcctcgggcgtggccgtgccgtgg
gcggtcgaggcgcagaagatcctcgccgaggactggaacgtcaaggcggacgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtggaggtcgagcggcacaatctgctg
cacccggaggaggagcagcgggtgccgtacgtgacgcggaagctgagcggcgccgagggc
ccggtggtggccgtctccgactggatgcgctcggtgccggaccagatcgcgcggtgggtg
ccggggacgtaccagtcgctgggcgccgacgggttcggcttcgccgacacccgtggcgcg
gcccggcgcttcttccacatcgacgcgcagtcgatcgtggtggcggtgctgaccgagctg
gcccgggagggcaaggtcgaccgctcggtgctcaagcaggcgatcgaccgctaccagctg
ctcgacgtgtcggcggccgatcccggggccgccgggggcgacgcgtag
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