Streptomyces spinosirectus: LXH13_34735
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Entry
LXH13_34735 CDS
T08958
Symbol
vanA-Sc
Name
(GenBank) D-alanine--(R)-lactate ligase VanA-Sc
KO
K15739
D-alanine---(R)-lactate ligase [EC:
6.1.2.1
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn01502
Vancomycin resistance
sspn02020
Two-component system
Module
sspn_M00651
Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09130 Environmental Information Processing
09132 Signal transduction
02020 Two-component system
LXH13_34735 (vanA-Sc)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LXH13_34735 (vanA-Sc)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
sspn01504
]
LXH13_34735 (vanA-Sc)
Enzymes [BR:
sspn01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.2 acid-alcohol ligases (ester synthases)
6.1.2.1 D-alanine---(R)-lactate ligase
LXH13_34735 (vanA-Sc)
Antimicrobial resistance genes [BR:
sspn01504
]
Gene sets
Vancomycin resistance modules
Vancomycin resistance, D-Ala-D-Lac type [MD:
M00651
]
LXH13_34735 (vanA-Sc)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
ATP-grasp_3
CPSase_L_D2
ATPgrasp_ST
TTL
Motif
Other DBs
NCBI-ProteinID:
UIR21886
LinkDB
All DBs
Position
7589434..7590474
Genome browser
AA seq
346 aa
AA seq
DB search
MSRLNVGIVFGGCSEEHPVSVKSAREVARNLDTAKYEPFYIGITKNGDWKLCDGPDPDWE
NGGSRPVVLSPDRGVHGLLVLEQGRYRTIRLDVVLPVLHGRLGEDGAMQGLLELSGIPYV
GCDVPSSALCMDKSLAYVVAGSAGIATPKFWTVAAGENIDTESLTYPVFVKPARSGSSFG
VSKVSRKEELHSAVETARHYDAKVLIEEAVVGSEIGCAILGNDLDLVAGEVDRIALSHGF
FRIHQEDEPESGSENSTAIVPADIPEASRARVQETAKAVYRALGCKGLARVDLFLTEDGQ
VVLNEVNTLPGMTSYSRYPRMMAAADLPLAEVLDRLVSLALTGKLR
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atgtccaggctgaacgtcggcatcgtattcgggggctgctccgaggagcaccccgtctcc
gtcaagtccgcgcgggaagtggcgcgaaacctcgataccgcgaagtacgaaccgttctac
atcggcatcacgaagaacggcgactggaagctctgcgacggccctgacccggactgggag
aacggcggcagccgtccggtcgtactgtcaccggaccgcggcgtccacggactcctcgta
ctggagcaggggcgataccgaacgatccgcctggacgtcgtgctgccggtgctgcacggc
agactcggtgaggacggcgcgatgcagggcctgctggaactctccggcatcccctatgtc
ggctgcgacgtgccgagttccgcgctgtgcatggacaagtcccttgcctacgtggtcgcc
gggagcgcgggaatcgccactccgaagttctggaccgtcgcggcgggcgagaacatcgat
accgaaagcctcacctaccccgtcttcgtgaagccggcccgttcgggatcgtccttcggc
gtcagcaaggtctcccgaaaggaagagctgcacagtgcggtggaaaccgctcggcactac
gacgcgaaggtgctgatcgaagaggccgtcgtcggcagcgagatcggatgcgccatcctg
ggcaacgacctggatctggtcgcgggcgaggtggatcgcatcgcgctctcgcacggcttc
ttcagaatccaccaggaggacgagcccgaaagcggctcggagaactcgacggcgatcgtg
ccggccgacatccccgaggcgtcgcgggcacgcgtgcaggagacggcgaaggccgtgtac
cgcgccttggggtgcaaggggctcgcgcgggtggacctgttcctcaccgaggacgggcaa
gtggtcctcaacgaggtcaacaccctgcccggcatgacctcgtacagccgctatccgagg
atgatggcggcggccgacctgccgctcgccgaagtgctcgaccgtctggtgtcgttggca
ttgaccgggaaactgcgatga
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