Streptomyces spongiicola: DDQ41_03610
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Entry
DDQ41_03610 CDS
T06937
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sspo
Streptomyces spongiicola
Pathway
sspo00010
Glycolysis / Gluconeogenesis
sspo00020
Citrate cycle (TCA cycle)
sspo00620
Pyruvate metabolism
sspo00785
Lipoic acid metabolism
sspo01100
Metabolic pathways
sspo01110
Biosynthesis of secondary metabolites
sspo01120
Microbial metabolism in diverse environments
sspo01200
Carbon metabolism
sspo01210
2-Oxocarboxylic acid metabolism
Module
sspo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sspo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DDQ41_03610 (aceE)
00020 Citrate cycle (TCA cycle)
DDQ41_03610 (aceE)
00620 Pyruvate metabolism
DDQ41_03610 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DDQ41_03610 (aceE)
Enzymes [BR:
sspo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DDQ41_03610 (aceE)
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Paralog
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Transket_pyr
PepSY_TM_like_2
Motif
Other DBs
NCBI-ProteinID:
AWK08174
UniProt:
A0ABM6V2W0
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Position
853698..856400
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AA seq
900 aa
AA seq
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MTDPVAMLPSELDQLPDRDTEETAEWAASLDAVTKAAGPHRAAYLMRRTLQHAEGVAGLD
LPKLLETDHVNTIPTAAEPLPAGDEEMERRITAWNRWNAAAMVTRGSRHGVGGHIATFAS
AAWLYETGFNHFFRGKEGGGTSEAGDSGDQLYIQGHASPGIYARAFLDGRLTEAHLDNFR
REAGGGGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRRIKDVSASHVWA
FLGDGEMDEPESTAALALAAREGLDNLTFVVNCNLQRLDGPVRANFKIVQELEAQFRGAG
WNVVKTLWGNAWDELFRLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALAE
MAKLLSDDRILECFHLSRGGHEPRKVYAAYKAAVEFKGAPTVILAQTVKGHTLGQGFASK
NANHQMKKLTVDEFKAMRDLLDLPIGDGDFADGQVPYGHPGADSPEVRYLKERRAALGGP
APARRVHPVAPLPAPAEKAFAAFDKGSGNQSVATTMAFVRLVKDLIRDRETGRRWVPIVP
DEARTFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYREAENGQILNEGITEAGSMADFIA
AASSYATHGETMIPFYIFYSMFGWQRTADQMWQLADQLGRGFLVGATAGRTTLTGEGLQH
ADGHSPVIAATNPAALSYDPAFAYEVAAIVKDGLRRMFGEARPDEDPDVFYYLTVYNEPM
PQPAKPEGVDEGIVRGLYRFRAGEGTADGPRIQLLASGTAIHWALEAQRLLAAEWGVTAD
VWSATSWTELRRDALEADEALLRGESRVPYVRQALEGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAQSVVVAALAQLARRGEVPASAVKEARERYGF
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtagccatgcttccgagcgagctcgaccagctcccggaccgtgacacc
gaggagaccgccgaatgggcggcctccctggacgccgtcaccaaggccgccggcccgcat
cgcgccgcgtacctgatgcgccgcaccctccagcacgccgagggtgtggcagggctcgat
ctgcccaagctcctggagacggaccacgtcaacaccatcccgaccgccgccgagccgctc
ccggccggcgacgaggagatggagcgccggatcaccgcctggaacaggtggaacgcggcg
gcgatggtcacccgcggctcccggcacggcgtcggcgggcacatcgccaccttcgcctcc
gccgcctggctctacgagaccggcttcaaccacttcttccgcgggaaggagggcgggggc
acctcagaggccggcgactccggcgaccagctgtacatccagggccacgcctcccccggc
atctacgcccgggccttcctcgacggccgcctcaccgaggcgcacctcgacaacttccgc
cgggaggccggcggcggcggtctgccgtcgtacccgcacccgcgccgactgccctggctg
tgggagttcccgacggtctccatggggctgggcccgctgtcggcgatctaccaggcgcgc
ttcaaccgctatctgaccagccgccgcatcaaggacgtctccgcgtcgcacgtctgggcg
ttcctcggcgacggcgagatggacgagcccgagtcgaccgcggcgctcgcgctggccgct
cgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcagcgcctcgacggc
ccggtgcgcgccaacttcaagatcgtgcaggagctggaggcccagttccgcggcgccggc
tggaacgtcgtgaagaccctctggggcaacgcctgggacgagctcttccggctcgacacc
acgggcgccctggtccgccggctgcgcgaggtcccggacgcgcaggtccagacgtaccag
acccgtgacgccgcctacatccgcgaggacttcttcggcaaggaccccgcgctcgccgag
atggcgaagctgctgagcgacgacaggatcctcgagtgcttccacctctcgcgcggcggt
cacgaaccgcgcaaggtgtacgccgcctacaaggccgccgtggagttcaagggcgccccg
acggtgatcctggcccagacggtcaagggccacacgctcggccagggcttcgcgtcaaag
aacgccaaccaccagatgaagaagctgacggtggacgagttcaaggcgatgcgggacctg
ctcgacctgccgatcggggacggcgacttcgccgacggacaggtgccctacggccacccc
ggcgccgactcccccgaggtccgctatctgaaggagcgccgcgcggcgctcggcggcccg
gccccggcccgccgcgtgcacccggtcgccccgctgcccgcgcccgccgagaaggcgttc
gccgccttcgacaagggctccggcaaccagtcggtggcgacgacgatggccttcgtccgc
ctggtcaaggacctgatccgcgacagggagaccgggcggcgctgggtgccgatcgtcccc
gacgaggcccgcaccttcggtatggagtcgctgttcccctcgctcggcatctactcgccg
aagggccagacgtacgagccggtcgaccgcgaccagctgatgtactaccgcgaggcggag
aacgggcagatcctcaacgagggcatcaccgaggccggctcgatggcggacttcatcgcc
gccgcttcgtcgtacgccacgcacggcgagacgatgatccccttctacatcttctactcg
atgttcggctggcagcggaccgccgaccagatgtggcagctcgccgaccagctcggcagg
ggcttcctcgtcggcgccacggccggccgcaccacgctgaccggcgagggcctgcagcac
gcggacggccactcgccggtgatcgcggcgacgaacccggcggcgctcagctacgacccg
gcgttcgcctacgaggtcgcggccatcgtcaaggacggtctgcgccgcatgttcggcgag
gcccgcccggacgaggacccggacgtcttctactacctgacggtctacaacgagccgatg
ccgcagcccgcgaagccggagggcgtggacgagggcatcgtccgcggcctgtaccggttc
cgggcgggcgagggcaccgcggacggcccgcgcatccagctcctcgcctcgggcacggcg
atccactgggcgcttgaggcacagcgcctgctggccgccgagtggggcgtcacggcggac
gtgtggtcggcgacctcctggaccgagctgcggcgcgacgcgctggaggccgacgaggcg
ctgctgcgcggcgagtcccgcgtcccgtatgtgcgccaggccctggagggcgccgagggc
ccggtgctcgcggtgagcgactacatgaggcaggtgccggaccagatcgcccagtgggtg
gagcaggactggtcgtcgctgggcgcggacggcttcggcctgtcggacacccgtgaggcg
gcgcgccgccacttcggtgtcgacgcgcagtcggtcgtggtcgcggcactggcacagctc
gcccgccgcggcgaggtgccggcctccgcggtcaaggaggcacgcgagcgttacggcttc
tga
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