Streptomyces spongiicola: DDQ41_04850
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Entry
DDQ41_04850 CDS
T06937
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sspo
Streptomyces spongiicola
Pathway
sspo00010
Glycolysis / Gluconeogenesis
sspo00020
Citrate cycle (TCA cycle)
sspo00620
Pyruvate metabolism
sspo00785
Lipoic acid metabolism
sspo01100
Metabolic pathways
sspo01110
Biosynthesis of secondary metabolites
sspo01120
Microbial metabolism in diverse environments
sspo01200
Carbon metabolism
sspo01210
2-Oxocarboxylic acid metabolism
Module
sspo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sspo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DDQ41_04850 (aceE)
00020 Citrate cycle (TCA cycle)
DDQ41_04850 (aceE)
00620 Pyruvate metabolism
DDQ41_04850 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DDQ41_04850 (aceE)
Enzymes [BR:
sspo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DDQ41_04850 (aceE)
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Gene cluster
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF5576
Motif
Other DBs
NCBI-ProteinID:
AWK08372
UniProt:
A0A2S1YWI3
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All DBs
Position
1132360..1135107
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETREWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAFLLDRLNETQLDGFRQ
EKSKFPDGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLIWDRTWDPLLARDRDGVLVNKLNTTPDGQFQTYATETGDYIRRHFFGDDQRLR
AMVENMTDHQVLMLGRGGHDHRKIFAAYSAARAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHLPIGDRELESGLPPYYHPGRDSEEIQYMHDRRRGLGGYVP
TRVVRSQPLALPGDKAYAAVKKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAFGFEIAHIVRDGLRRMYGGDAEHPHGEDVFYYLTVYNEPIQH
PAEPEDVDVDGILKGIHRFREGQAGRIPAQIMASGVAVPWALQAQRILAEEWDVKAGVWS
ATSWNELRREAVAAEEYNLLHPEEEQRVPYVTRKLGGAEGPFVAVSDWMRSVPDQIARWV
PGRYTSLGADGFGFADTRGAARRYFHIDAQSIVLAVLTELAHEGRVDRSVLKQALDRYQL
LDVAAADPGPAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatcagatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gacttcgatccggaggagacccgggagtggctcgactcgctcgacgccgccgtcgacgag
cgcggccgtgagcgggcccgctacctcatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtgaacaccatcgcgaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcggaagatcctcaacgccacccgctgg
aacgccgcggtgatggtgtcccgcgcccagcgccccgggatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctccctctacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccatgcctcgcccggcgtc
tacgcccgcgcgttcctgctggaccggctgaacgagacccagctcgacggcttccgccag
gagaagtcgaagttccccgacggtctgtcgtcgtacccgcacccccggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgatcggggcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggtatcgccgacacctcccgctcgcacgtgtgg
gccttcctcggcgacggcgagatggacgagcccgagtcgctcggccagctctcgatcgcc
gcccgcgagggcctggacaacctgaccttcgtggtgaactgcaacctgcagcggctcgac
ggcccggtacgcggcaacggcaagatcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtgatcaagctgatctgggaccgcacctgggacccgctgctcgcgcgggac
cgcgacggagtgctggtcaacaagctgaacacgacaccggacggccagttccagacgtac
gccacggagacgggcgactacatccgccggcacttcttcggcgacgaccagcggctgcgc
gccatggtcgagaacatgaccgaccaccaggtcctgatgctgggccgcggcggccacgac
caccggaagatcttcgcggcgtactccgcggcccgcgcccacaagggccagccgacggtg
atcctcgcccagacggtcaagggctggacgctgggaccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagggcttccgcgaccggctgcac
ctcccgatcggcgaccgcgagctggagtccggcctgccgccgtactaccacccgggccgc
gactcggaggagatccagtacatgcacgaccgccgcaggggcctgggcgggtacgtgccg
acccgggtggtgcggtcgcagccactggccctgcccggcgacaaggcgtacgcggccgtg
aagaagggctcggggcagcagtcgatcgccaccaccatggcgttcgtcaggctgctgaag
gacctcatgcgggacaaggagatcggcaggcggttcgtgctgatcgctccggacgagtac
cgcacgttcggcatggactcgttcttcccgagcgccaagatctacaacccgctcggccag
cagtacgaggcagtggaccgcgagctgctgctggcgtacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcaccgcctcgctgatcgcggccggctcg
gcctacgccacccacggcgagccgctgatcccggtctacgtcttctactcgatgttcggt
ttccagcggaccggcgaccagttctggcagatggccgaccagctctcgcgcggattcgtc
ctcggcgcgaccgccgggcgcacgaccctgaccggcgagggcctgcagcacgcggacggc
cactcccagctgctggcctccaccaacccggcctgcgtcgcgtacgacccggcgttcggc
ttcgagatcgcgcacatcgtccgggacggcctgcgccggatgtacggcggcgacgccgag
cacccgcacggcgaggacgtcttctactacctgaccgtctacaacgagccgatccagcac
ccggccgagcccgaggacgtcgacgtggacggcatcctcaagggcatccaccgcttccgg
gaaggccaggcgggccggatcccggcgcagatcatggcgtccggcgtcgccgtcccctgg
gcccttcaggcccagcggatcctcgccgaggagtgggacgtgaaggccggcgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtggcggccgaggagtacaacctgctc
caccccgaggaggagcagcgcgtcccgtatgtgacgcggaagctcggcggcgccgaggga
cccttcgtggcggtgtccgactggatgcgcagcgtcccggaccagatcgcccgctgggtg
cccggccgctacacctcgctgggtgcggacggcttcggcttcgcggacacccggggcgcg
gcccgccgctacttccacatcgacgcgcagtcgatcgtgctggcggtcctcaccgaactc
gcccacgagggcagggtcgaccgctcggtgctgaagcaggccctggaccgctaccagctg
ctggacgtggcggcggccgacccgggccccgcgggcggcgacgcgtag
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