Streptomyces subrutilus: CP968_11395
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Entry
CP968_11395 CDS
T07087
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ssub
Streptomyces subrutilus
Pathway
ssub00020
Citrate cycle (TCA cycle)
ssub00630
Glyoxylate and dicarboxylate metabolism
ssub00785
Lipoic acid metabolism
ssub01100
Metabolic pathways
ssub01110
Biosynthesis of secondary metabolites
ssub01120
Microbial metabolism in diverse environments
ssub01200
Carbon metabolism
ssub01210
2-Oxocarboxylic acid metabolism
Module
ssub_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ssub_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ssub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP968_11395
00630 Glyoxylate and dicarboxylate metabolism
CP968_11395
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP968_11395
Enzymes [BR:
ssub01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP968_11395
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP968_11395
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP968_11395
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP968_11395
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEU78816
UniProt:
A0A5P2UHS6
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All DBs
Position
2674629..2678561
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AA seq
1310 aa
AA seq
DB search
MSPQSPSNSTTTTEGAGGGKNPASGFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGAAAPVKAEEPKTSPTTDGASAQAAPAVAAAPRATAASGAADTGSVSGSSGATAAPAPA
PTSAAAPTPVSAPAPAPATPSGAPAVTATSQAQAAAPAAPAPQAAAPAAAPSSAAPKAAP
AAEAPAGPELVTLRGPSAAVVKNMNASLEVPTATSVRAVPVKLLFDNRIVINNHLKRARG
GKISFTHLIGYAMVQAIKAMPSMNHSFAEKDGKPTLVKPEHINFGLAIDLVKPNGDRQLV
VAGIKKAETLNFFEFWQAYEDIVRRARVGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMP
GQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVANL
LLGENGFYDDVFEALRIPYEPVRWLRDIDASHDDDVTKAARVFELIHSYRVRGHVMADTD
PLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSMMKLRDILGVLRDSYCRTTGVEF
MHIQDPKQRRWIQDRIERPHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGG
ESVIPLLDAVIDSAAEARLEEVAIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMH
GSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVVRAKQDIINKGGTDFT
VLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYAT
DVARMIEAPIFHVNGDDPEAVVRIARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFT
QPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREAATQPAA
GAPVAPVQVAQVFPVAVNTAISQEFVKRIAEAQVNIPDNVTVHPRLLPQLQRRAAMIDEG
TIDWGMGETLAFGSLLMEGTPVRLSGQDSRRGTFGQRHAVLIDRETGEDYTPLQYLSDDQ
ARYNVYDSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNGAQTVVDEFISSAEQKWG
QTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPTLPSNYFHLLRWQVHNPH
HKPLIVFTPKSMLRLKAAASKAEEFTTGSFRPVIGDSTVDPNAVRKVVFCAGKVYYDLEA
EREKRGITDTAIIRIERLYPLAGAELQAEIAKFPNAAKYIWAQEEPANQGAWPFIALNLI
DHLDLAVGADVPAGERLRRISRPHGSSPAVGSAKRHQAEQQLLLNEVFEA
NT seq
3933 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgaccaccacgaccgaaggagcagggggcgggaag
aaccctgcctcaggcttcggcgccaatgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaactcggtcgaccgggcctggtgggacttcttcgccgactacaagccg
gggggcgctgccgctcccgtgaaggccgaagagccgaagacgtccccgacgacggacggc
gcctccgcacaggccgcccccgccgtcgccgcggccccgcgggccaccgccgcctcgggg
gcggcggacaccggttccgtctccggctcctccggagcgacggccgcacccgcgcccgcg
ccgacctctgccgccgcgcccacgcccgtgtcagctcctgcccctgctcctgccaccccc
tctggtgcccctgctgtgactgccacctcccaggcccaggccgccgcaccggccgcgccc
gcccctcaggccgcggctccggccgccgctccctcctccgcagccccgaaggccgcgcct
gccgccgaggcccccgcgggccccgagctggtgacgctccgcggcccgtccgctgccgtc
gtcaagaacatgaacgcctcgctggaggtgcccacggccacgtccgtgcgcgccgtcccg
gtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccggggc
gggaagatctccttcacccacctcatcggctacgcgatggtgcaggccatcaaggccatg
ccgtcgatgaaccactccttcgcggagaaggacggcaagccgaccctggtcaagccggag
cacatcaacttcggcctggcgatcgacctggtgaagccgaacggcgaccgccagctcgtc
gtcgccggcatcaagaaggccgagaccctcaacttcttcgagttctggcaggcgtacgag
gacatcgtccgccgcgcccgcgtcggcaagctgacgatggacgacttcaccggcgtcacg
gtctcgctgaccaaccccggcggcctgggcaccgtccactccgtgccccgcctgatgccc
ggacagtcggtcatcatgggcgtcggctccatggactaccccgccgagttccagggcacc
tcgcaggacaccctgaacaagctgggcatctccaaggtcatgacgctgacctcgacctac
gaccaccgggtcatccagggcgcggcctccggcgagttcctgcggatcgtcgcgaacctg
ctgctcggcgagaacggcttctacgacgacgtcttcgaggcgctgcgcatcccgtacgag
ccggtccgctggctccgggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcc
cgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgac
ccgctggagtacaagcagcgcaagcaccccgacctcgacatcaccgagcacggcctcacc
ctgtgggacctggagcgcgagttcgcggtcggcggcttctccggcaagtcgatgatgaag
ctccgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcgtcgagttc
atgcacatccaggacccgaagcagcgccgctggatccaggaccgcatcgagcgcccgcac
agcaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgcggaggcc
ttcgagaccttcctgcagacgaagtacgtcggccagaagcggttctccctggagggcggc
gagtccgtcatcccgctgctcgacgcggtcatcgactcggccgccgaggcccgcctcgaa
gaggtcgcgatcggcatggcacaccgcggccggctgaacgtgctggcgaacatcgtcggc
aagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtccatgcac
ggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggcctggacggc
gagcagatcaaggtctcgctcgtcgccaacccctcccacctggaggccgtggacccggtc
ctggagggcgtggtccgcgccaagcaggacatcatcaacaagggcggcacggacttcacg
gtcctgccggtcgccctgcacggcgacgcggccttcgcgggccagggcgtggtcgcggag
acgctgaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacgtggtcatc
aacaaccaggtcggcttcaccgccgccccggagtcctcgcgttcctcgatgtacgcgacc
gacgtggcccgcatgatcgaggcgccgatcttccacgtgaacggcgacgacccggaggcc
gtggtccgcatcgcgcggctcgccttcgagttccgccaggcgttcaacaaggacgtggtc
atcgacctcatctgctaccgccgccgcggccacaacgagtccgacaacccggccttcacg
cagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgag
tccctcatcggtcgtggcgacatcacgctggaagaggccgagcaggcgctccaggacttc
cagggccagttggagaaggtgttcgcggaggtccgcgaggccgccacgcagccggccgcc
ggcgccccggtggcgcccgtgcaggtcgcgcaggtgttcccggtcgccgtgaacaccgcg
atctcccaggagttcgtgaagcggatcgccgaggcccaggtcaacatccccgacaacgtc
accgtgcacccgcgcctgctgccgcagctgcagcgccgcgcggcgatgatcgacgagggc
accatcgactggggcatgggcgagaccctggccttcggttcgctgctgatggagggcact
ccggtccggctctccggccaggactcgcgccgcggcacgttcggccagcgccacgcggtc
ctcatcgaccgggagaccggcgaggactacaccccgctgcagtacctgtcggacgaccag
gcccgctacaacgtctacgactcgctgctctccgagtacgcggccatgggcttcgagtac
ggctactcgctggcccgcccggacgcgctggtgctgtgggaggcgcagttcggcgacttc
gtcaacggcgcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggc
cagacctccggcgtcacgctgctgctgccgcacggctacgagggccagggcccggaccac
tcgtccgcgcgtcccgagcgcttcctgcagatgtgcgcgcaggacaacatgacggtcgcg
atgccgaccctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcac
cacaagccgctcatcgtcttcaccccgaagtcgatgctgcgcctgaaggccgcggcgtcg
aaggcggaggagttcaccaccggttcgttccgtccggtcatcggcgacagcacggtggac
ccgaacgcggtccgcaaggtcgtcttctgcgcgggcaaggtctactacgacctggaggcc
gagcgggagaagcgcggcatcacggacaccgcgatcatccgcatcgagcggctgtacccg
ctggccggcgcggaactccaggcggagatcgccaagttcccgaacgccgcgaagtacatc
tgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctgaacctgatc
gaccacctcgacctggcggtcggcgcggacgtcccggcgggcgagcgcctgcggcgcatc
tcgcgcccgcacggctcgtccccggcggtgggctcggccaagcggcaccaggcggagcag
cagctcctcctgaacgaggtcttcgaggcctag
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