Streptomyces subrutilus: CP968_22945
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Entry
CP968_22945 CDS
T07087
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ssub
Streptomyces subrutilus
Pathway
ssub00010
Glycolysis / Gluconeogenesis
ssub00020
Citrate cycle (TCA cycle)
ssub00620
Pyruvate metabolism
ssub00785
Lipoic acid metabolism
ssub01100
Metabolic pathways
ssub01110
Biosynthesis of secondary metabolites
ssub01120
Microbial metabolism in diverse environments
ssub01200
Carbon metabolism
ssub01210
2-Oxocarboxylic acid metabolism
Module
ssub_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP968_22945 (aceE)
00020 Citrate cycle (TCA cycle)
CP968_22945 (aceE)
00620 Pyruvate metabolism
CP968_22945 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP968_22945 (aceE)
Enzymes [BR:
ssub01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP968_22945 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QEU80757
UniProt:
A0A5P2UVI3
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All DBs
Position
complement(5172473..5175205)
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AA seq
910 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSSDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLSEQQLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMQARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLIWDRSWDPLLAQDRDGILVNKMNSTPDGQFQTYATESGAYIREHFFGGDQRLR
AMVENMTDQQIQHLGRGGHDHKKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHIPVTDAQLEGGAPPYYHPGRNSPEIQYMHDQRSAHGGYVP
TRVVRAKPLQLPDEKAYAAARKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYGYEIAHIVRDGLRRMYGPDAEDVFYYLTVYNEPIQHPAEPA
DVDVDGILKGIHRVSRGTSGTIGAQIMASGVAVPWALEAQRLLAEEWNVRADVWSATSWN
ELRREAVAVEEHNLLHPEEEQRVPYVTRKLSGAEGPFVAVSDWMRSVPDQISRWVPGTYT
SLGADGFGFADTRGAARRFFHIDAQSVVLATLTELARDGKIDRSVLKQAVDRYQLLDVTA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaacccgatcatcattggcggcctgcccagtcaggtcccg
gacttcgatccggaggagacgcaggagtggctcgactccctcgacgcggccgtcgacgag
cggggccgtgagcgcgcccgctacctgatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgctcctcggactacgtcaacaccatcgcgaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaaggtcctcaacgccacccggtgg
aacgcggccgtcatggtctcgcgcgcccagcgtcccgggatcggggtcggcggccacatc
gccaccttcgcctcctccgcctccctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccagatcttcttccaggggcacgcctcccccggcatc
tacgcccgcgcgttcctcctggaccggctctccgagcagcagctcgacgcgttccggcag
gagaagtcgaaggccccgtacggcctgtccagctacccgcacccgcgactgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggcgcgatctaccaggcc
cggatgaaccgctacatgcaggcgcgcggcatcgccgacacctcgaagtcgcacgtctgg
gcgtacctgggcgacggcgagatggacgagccggagtcgctcggccagctgtcgatcgcg
gcccgcgaggggctggacaacctgaccttcgtggtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctgatctgggaccgctcctgggacccgctgctggcgcaggac
cgcgacggcatcctggtcaacaagatgaactccacgcccgacggccagttccagacgtac
gccaccgagtcgggcgcgtacatccgcgagcacttcttcggcggcgaccagcggctgcgc
gcgatggtcgagaacatgaccgaccagcagatccagcacctgggccgcggcggccacgac
cacaagaaggtctacgcggcgtacgcggcggccaaggcccacaagggccagccgacggtg
atcctggcgcagacggtcaagggttggacgctgggcccgaacttcgagggccgcaacgcg
acgcaccagatgaagaagctgacggtcgacgacctgaagcgcttccgcgaccgcctgcac
atcccggtcacggacgcgcagttggagggcggcgcccctccgtactaccacccgggccgc
aactcccccgagatccagtacatgcacgaccagcgcagcgcgcacggcggctacgtgccg
acgcgcgtggtgcgcgcgaagccgctgcagctgccggacgagaaggcgtacgcggcggcc
cgcaagggctcgggccagcagtcgatcgccacgacgatggccttcgtccgcatcctgaag
gacctgatgcgggacaaggagatcggcaagcggttcgtgctgatcgcgcccgacgagtac
cgcaccttcggcatggacgcgttcttcccgagcgccaagatctacaacccgctgggtcag
cagtacgaggcggtcgaccgcgagctgctgctcgcgtacaaggagtcgccgacgggccag
atgctgcacgacggcatttcggaggcgggctgcacggcctcgctgatcgcggcgggctcg
gcgtacgcgacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcggc
ttccagcgcacgggtgaccagttctggcagatggccgaccagctcgcgcgcggtttcgtc
ctgggcgcgaccgcgggccggaccaccctcacgggtgagggcctccagcacgccgacggc
cattcccagctgctggcctcgaccaacccgggctgcgtggcgtacgacccggcctacggg
tacgagatcgcccacatcgtgcgggacggtctgcgccggatgtacggtcccgacgccgag
gacgtcttctactacctgaccgtctacaacgagccgatccagcacccggccgagccggcc
gacgtggacgtcgacggcatcctcaagggcatccaccgggtgtcgcggggcacctcgggc
accatcggggcgcagatcatggcctcgggcgtggcggtgccgtgggcgctggaggcgcag
cggctgctggccgaggagtggaacgtccgggcggacgtgtggtcggcgacctcgtggaac
gagctgcgccgcgaggccgtcgcggtggaggagcacaacctgctgcacccggaggaggag
cagcgggtcccgtacgtgacgcgcaagctgtcgggtgccgaggggccgttcgtggccgtc
tcggactggatgcgctcggtgccggaccagatctcgcgctgggtgccgggcacgtacacc
tcgctgggcgcggacggcttcggcttcgcggacacgcgcggcgccgctcggcgcttcttc
cacatcgacgcccagtcggtggtgctggcgacgctgaccgagctggcgcgggacgggaag
atcgaccgttcggtgctgaagcaggccgtcgaccggtaccagctgctcgacgtcacggcg
gccgacccgggcgccgcgggcggcgacgcctga
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