Streptomyces subrutilus: CP968_23765
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Entry
CP968_23765 CDS
T07087
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ssub
Streptomyces subrutilus
Pathway
ssub00010
Glycolysis / Gluconeogenesis
ssub00020
Citrate cycle (TCA cycle)
ssub00620
Pyruvate metabolism
ssub00785
Lipoic acid metabolism
ssub01100
Metabolic pathways
ssub01110
Biosynthesis of secondary metabolites
ssub01120
Microbial metabolism in diverse environments
ssub01200
Carbon metabolism
ssub01210
2-Oxocarboxylic acid metabolism
Module
ssub_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP968_23765 (aceE)
00020 Citrate cycle (TCA cycle)
CP968_23765 (aceE)
00620 Pyruvate metabolism
CP968_23765 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP968_23765 (aceE)
Enzymes [BR:
ssub01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP968_23765 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QEU80899
UniProt:
A0A5P2URB2
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Position
complement(5351623..5354307)
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AA seq
894 aa
AA seq
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MSDPVGKLPSELDQLPDRDTEETAEWAASLDAVAQAAGTRRAEYLLRRTLQHAEAAGLAL
PKLLETDYVNTIPTAAEPEFPGDEEMEARITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFQHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRISEQQLDNFRQESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLHNRSIKDTANSHVWAFLGDGEM
DEPESTAALALASREQLDNLTFVINCNLQRLDGPVRANFRVVQELEAQFRGAGWNVIKSL
WGSAWDELFRLDTTGALVRRLREVPDAQFQTYATRDVAYIRDHFFGADPALVQLASVLSD
AKIAECFHTSRGGHEPRKVYAAYKAALEHKGAPTVILAQTVKGYTLGAGFESKNANHQMK
KLTIDEFKSMRDKLGLPIPDSAFADGQVPYGHPGADSPEVRYLNERRAALGGPAPARKVK
PVALPAPADRSFAPLLKGSGKQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAACTSYATH
GEPMIPFYIFYSMFGWQRTADQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVKDGLRRMYGEQPEDVFYYLTVYNEPKVQPAIPEGVEEG
IVKGLYRFNTAADLAEAAPAAGAPKLQLLASGTAIHWALDAQKLLAAEWNVAADVWSATS
WGELRREALECDEALLRGEVRTPYVTRALEGAAGPVLAVSDWMRQVPDQISQWVEQDWTS
LGTDGFGLSDTRAGARRHFGVDAQSIVVAALAQLARRGEVPASSVKEARERYGL
NT seq
2685 nt
NT seq
+upstream
nt +downstream
nt
atgtccgaccccgtaggaaagcttccgagcgagctcgaccagctcccggaccgcgacacc
gaggagaccgccgaatgggcggcctcactcgacgccgtcgcccaggccgccggtacgcgc
cgcgccgaatacctgctccgccgtacgctccagcacgccgaggccgccggcctcgcgctg
ccgaagctgctggagacggactacgtcaacaccatccccaccgccgcggagcccgagttc
cccggtgacgaggagatggaagcccggatcaccgcctggaaccgctggaacgcggccgcc
atggtgacccgcggctccaagcacggcgtcggcggccacatcgccaccttcgcctccgcc
gcgtggctgtacgagaccggcttccagcacttcttccgcgggaaggaggccgacgggtcg
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggatctccgagcagcagctcgacaacttccgccaggagtccggcggcaacggt
ctgccgtcctacccgcacccgcggcgcctgccgtggctgtgggagttcccgacggtctcc
atgggcctcggcccgctgtcggcgatctaccaggcgcggttcaaccgctacctgcacaac
cgcagcatcaaggacaccgccaactcgcacgtctgggccttcctgggcgacggcgagatg
gacgagcccgagtcgaccgcggccctggccctcgcctcccgcgagcagctcgacaacctg
accttcgtgatcaactgcaacctgcagcgcctcgacggtccggtccgcgcgaacttccgc
gtggtccaggagctggaggcccagttccgcggcgccggctggaacgtcatcaagtcgctg
tggggctccgcctgggacgagctgttccggctcgacaccacgggcgccctggtgcgccgc
ctgcgcgaggtgcccgacgcgcagttccagacgtacgcgacccgcgacgtggcctacatc
cgcgatcacttcttcggcgcggaccccgcgctcgtgcagctggcctcggtgctctccgac
gccaagatcgccgagtgcttccacacctcccgcggcggccacgagccccgcaaggtctac
gccgcgtacaaggccgccctggagcacaagggcgcgccgacggtgatcctcgcgcagacc
gtcaagggctacacgctgggcgccgggttcgagtcgaagaacgcgaaccaccagatgaag
aagctgacgatcgacgagttcaagagcatgcgcgacaagctcggactcccgatcccggac
agcgccttcgccgacggccaggtcccctacggccacccgggcgcggacagccccgaggtc
cggtacctcaacgaacgccgtgcggcgctcggcggcccggccccggcccgcaaggtcaag
cccgtggccctgcccgctccggcggaccgctccttcgccccgctgctcaagggctccggc
aagcaggagatggccaccaccatggccttcgtccggctcgtcaaggacctgatgcgggac
aaggagaccggcaggcgctgggtgccgatcgtccccgacgaggcccgcaccttcggcatg
gagtcgctcttcccgtcggccggcatctactcgccgctgggccagacgtacgagccggtc
gaccgcgaccagctcatgtactacaaggaagccaaggacggccagatcctcaacgagggg
atcaccgaggccggcgccatggccgacttcatcgccgcctgcacgtcgtacgcgacgcac
ggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcgcaccgcc
gaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccaccgcc
ggccgcaccacgctgaccggcgagggcctgcagcacgcggacggccactcgcacctgatc
gcgtccacgaacccggcgtcgctcaactacgacccggccttcgcgtacgagatcgcggtg
atcgtcaaggacggtctgcgccggatgtacggcgagcagccggaggacgtcttctactac
ctgacggtctacaacgagccgaaggtgcagcccgcgatccccgagggcgtcgaagagggc
atcgtcaagggcctgtaccgcttcaacaccgcggcggacctcgccgaggcggccccggcc
gccggggcgccgaagctgcagctgctggcgtcgggcacggcgatccactgggcgctcgac
gcccagaagctgctcgccgccgagtggaacgtggccgccgacgtctggtccgccacctcc
tggggcgagctgcgccgcgaggcgctggagtgcgacgaggcgctgctgcgcggcgaggtg
cgcaccccgtacgtcacccgcgccctggagggcgccgcaggcccggtcctggccgtgtcc
gactggatgcgccaggtcccggaccagatcagccagtgggtcgagcaggactggacctcg
ctcggtacggacggcttcggcctctccgacacccgcgcgggcgcccgccgccacttcggc
gtcgacgcccagtcgatcgtggtggccgcgctggcccagctcgcccgccgcggcgaggtg
ccggcgtcctccgtcaaggaggcccgggagcgctacggcctctga
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