Streptomyces sp. SirexAA-E: SACTE_1862
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Entry
SACTE_1862 CDS
T01601
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ssx
Streptomyces sp. SirexAA-E
Pathway
ssx00010
Glycolysis / Gluconeogenesis
ssx00020
Citrate cycle (TCA cycle)
ssx00620
Pyruvate metabolism
ssx00785
Lipoic acid metabolism
ssx01100
Metabolic pathways
ssx01110
Biosynthesis of secondary metabolites
ssx01120
Microbial metabolism in diverse environments
ssx01200
Carbon metabolism
ssx01210
2-Oxocarboxylic acid metabolism
Module
ssx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SACTE_1862
00020 Citrate cycle (TCA cycle)
SACTE_1862
00620 Pyruvate metabolism
SACTE_1862
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SACTE_1862
Enzymes [BR:
ssx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SACTE_1862
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AEN09769
UniProt:
G2NBT2
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All DBs
Position
2068935..2071754
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AA seq
939 aa
AA seq
DB search
MGAAYSSLPGGTFPGYQAPKSTTEQRRNSVASGSDRNPIIIGGLPSQVPDFDPEETQEWL
DSLDAAVDERGRERARYLMLRLIERAREKRVAVPEMRSTDYVNTIATKDEPFFPGDEEIE
RKVLNATRWNAAVMVSRAQRPGIGVGGHIATFASSASLYDVGFNHFFRGKDDGLGGDQIF
FQGHASPGIYARAFLLDRLSEAQLDGFRQEKSKAPNGLSSYPHPRLMPDFWEFPTVSMGL
GPLGAIYQARMNRYMEARGIADTSASHVWAYLGDGEMDEPESLGQLSIAAREGLDNLTFV
VNCNLQRLDGPVRGNGKIIQELESQFRGAGWNVIKLVWDRTWDPLLAQDRTGILVNKLNT
TPDGQFQTYATETGAYIRDHFFGGDPRLRDMVKDMSDDQILHLGRGGHDHRKVYAAYAAA
KAHKGQPTVILAQTVKGWTLGPNFEGRNATHQMKKLTVEDLKRFRDRLHLPIADKELEDG
NPPYYHPGRDSEEIQYMHDRRKGLGGYVPTRVVRAKPLALPDDKVYAAAKKGSGQQSIAT
TMAFVRVLKDLMRDKEIGKRFVLIAPDEYRTFGMDAFFPSAKIYNPLGQQYESVDRELLL
TYKESPTGQMLHDGISEAGCTASLIAAGSAYATHGEPLIPVYVFYSMFGFQRTGDQFWQM
ADQLARGFVLGATAGRTTLTGEGLQHADGHSQLLASTNPGCVAYDPAFGYEIAHIVKDGL
RRMYGEDSEDVFYYLTVYNEPIQHPAEPADVDVDGILKGVYRYRGGEKGRIPAQIMASGV
AVPWAVEAQRILADEWDVQADVWSATSWNELRREAVDVERYNLLHPEEEQRVPYVTRKLS
GAQGPFVAVSDWMRSVPDQIARWVPGTYQSLGADGFGFADTRGAARRFFHIDAQSIVLAV
LTELAKEGKIDRSALKTAVDRYELLDVAAADPGAAGGDA
NT seq
2820 nt
NT seq
+upstream
nt +downstream
nt
atgggggcggcgtacagcagccttcccgggggtacgttccccggataccaggccccgaag
agcaccaccgaacagcgaaggaacagcgtggcttccggatccgatcgcaacccgatcatc
attggcggccttccgagccaggtcccggacttcgatcctgaagagacccaggaatggctc
gactccctcgacgccgccgtcgacgagcgaggccgtgaacgtgcccgctacctgatgctc
cggctcatcgagcgcgcgcgtgagaagcgtgtcgccgtgccggagatgcgcagcacggac
tacgtgaacacgatcgccacgaaggacgagccgttcttccccggcgacgaggagatcgag
cgcaaggtcctcaacgcgacccggtggaacgcggcggtgatggtctcgcgcgcccagcgt
ccggggatcggcgtcggcgggcacatcgccaccttcgcctcctccgcctcgctgtacgac
gtgggcttcaaccacttcttccggggcaaggacgacgggctgggcggcgaccagatcttc
ttccagggacacgcctcccccggtatctacgcccgcgccttcctgctcgaccggctgagc
gaggcccagctggacggcttccggcaggagaagtcgaaggcgcccaacgggctgtccagc
tacccgcacccgcggctgatgccggacttctgggagttcccgaccgtctcgatgggcctc
ggcccgctaggtgcgatctaccaggcgcggatgaaccgctacatggaggcgcgcggcatc
gccgacacctccgcctcgcacgtctgggcctacctcggcgacggcgagatggacgagccc
gagtcgctcggccagctgtccatcgcggcccgcgagggactggacaacctcaccttcgtg
gtcaactgcaacctccagcgcctcgacgggccggtgcggggcaacggcaagatcatccag
gagctggagtcgcagttccgcggcgccggctggaacgtgatcaagctcgtctgggaccgg
acctgggacccgctgctcgcccaggaccgcacgggcatcctggtcaacaagctgaacacc
accccggacggccagttccagacgtacgccaccgagaccggggcgtacatccgggaccac
ttcttcggtggtgacccgcgcctgcgcgacatggtcaaggacatgtccgacgaccagatc
ctgcacctgggccgcggcgggcacgaccaccgcaaggtctacgcggcctacgcggcggcc
aaggcccacaagggccagccgacggtgatcctggcccagacggtcaagggctggacgctc
ggcccgaacttcgagggccgcaacgcgacgcaccagatgaagaagctgaccgtcgaggac
ctcaagcggttccgcgaccggctgcacctcccgatcgcggacaaggagctggaggacggc
aacccgccgtactaccacccgggccgggactcggaggagatccagtacatgcacgaccgc
cgcaagggcctgggcggttacgtcccgacccgtgtggtgcgcgcgaagccgctcgccctg
ccggacgacaaggtgtacgccgctgcgaagaaggggtccggtcagcagtcgatcgccacg
accatggcgttcgtccgcgtcctgaaggacctcatgcgggacaaggagatcggcaagcgt
ttcgtgctgatcgcacccgacgagtaccgcaccttcggcatggacgccttcttcccgagt
gcgaagatctacaacccgctgggtcagcagtacgagtccgtggaccgcgagctgctgctc
acgtacaaggagtccccgaccgggcagatgctgcacgacgggatctccgaggcgggctgc
acggcctcgctgatcgccgcgggctcggcgtacgccacccacggcgagccgctgatcccg
gtgtacgtcttctactcgatgttcggtttccagcgcaccggcgaccagttctggcagatg
gccgatcagctcgcacgcggtttcgtgctgggcgcgaccgccgggcgcacgacgctgacc
ggcgagggcctccagcacgcggacggccactcgcagctgctcgcctcgaccaacccgggc
tgtgtcgcgtacgacccggcgttcgggtacgagatcgcgcacatcgtcaaggacggtctg
cgcaggatgtacggcgaggacagcgaggacgtcttctactacctcaccgtctacaacgag
ccgatccagcacccggccgagccggccgacgtggacgtcgacggcatcctcaagggggtg
taccgctaccgcggcggcgagaagggccggatcccggcccagatcatggcgtcgggcgtg
gcggtgccgtgggcggtcgaggcgcagcggatcctcgcggacgaatgggacgtgcaggcg
gacgtctggtcggcgacctcctggaacgagctgcgccgcgaggccgtcgacgtcgagcgg
tacaacctgctgcaccccgaggaggagcagcgtgtcccgtacgtgacgcggaagctgtcg
ggtgcgcagggaccgttcgtggcggtgtcggactggatgcgttcggtgcccgaccagatc
gcccgctgggtgcccgggacgtaccagtcgctgggcgcggacggcttcggcttcgcggac
acgcggggcgctgcccgccgcttcttccacatcgacgcgcagtcgatcgtgctcgcggtg
ctgaccgagctggcgaaggaggggaagatcgaccgttcggcgctgaagacggcggtcgac
cgctacgagctgctggacgtggccgcggcggaccccggcgcggcgggcggcgacgcgtaa
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