Symphalangus syndactylus (siamang): 129463687 Help Entry 129463687         CDS       T10134                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism ssyn  Symphalangus syndactylus (siamang) Pathway ssyn04022   cGMP-PKG signaling pathway ssyn04068   FoxO signaling pathway ssyn04081   Hormone signaling ssyn04140   Autophagy - animal ssyn04152   AMPK signaling pathway ssyn04211   Longevity regulating pathway ssyn04213   Longevity regulating pathway - multiple species ssyn04910   Insulin signaling pathway ssyn04920   Adipocytokine signaling pathway ssyn04923   Regulation of lipolysis in adipocytes ssyn04930   Type II diabetes mellitus ssyn04931   Insulin resistance ssyn04932   Non-alcoholic fatty liver disease ssyn04935   Growth hormone synthesis, secretion and action ssyn05010   Alzheimer disease ssyn05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:ssyn00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     129463687 (IRS2)    04022 cGMP-PKG signaling pathway     129463687 (IRS2)    04152 AMPK signaling pathway     129463687 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     129463687 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     129463687 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     129463687 (IRS2)    04923 Regulation of lipolysis in adipocytes     129463687 (IRS2)    04920 Adipocytokine signaling pathway     129463687 (IRS2)    04935 Growth hormone synthesis, secretion and action     129463687 (IRS2)   09149 Aging    04211 Longevity regulating pathway     129463687 (IRS2)    04213 Longevity regulating pathway - multiple species     129463687 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     129463687 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     129463687 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     129463687 (IRS2)    04932 Non-alcoholic fatty liver disease     129463687 (IRS2)    04931 Insulin resistance     129463687 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  129463687 NCBI-ProteinID:  XP_055100369 LinkDB All DBs Position 15:10444089..10476036 Genome browser AA seq 1331 aa AA seqDB search MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCNSCR VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAATVPPAGPAPTSAGGRTFPASGG GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFS AALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGADSDQYVLMSSPVGRILEEERLEPQATP GAGPTQPPHPVVPSPVRPSGGLGGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLP PEPKSPGEYINIDFGESGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSR QRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEATPYPPLPPRPSASPSSSLQP PPPPPPPGELYRLPPASAAATAQGPGAASLSSSDTGDNGDYTEMAFGVAATPPQPIAAPP KPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSET FSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAL PAPPLAPQGRPWTPGQPGGLIGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQP QPQPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASIDFLS HHLKEATIVKE NT seq 3996 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcacgggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg acggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccggagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacctgacaggcgtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctcatgaacatccgccgctgcggccactcggacagcttctttttcatcgaggtgggc cgctcagccgtcacaggccccggcgagctgtggatgcaggcggacgactcggtggtggcg cagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttc cggccgcgcagcaagagccagtcgtcggggtcgtcggccacacaccccatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctgccccctagccagacaggcctggtgcgc cgctcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcaactcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggggcggcggccgcgggcgcc aggccggtgtcggtggctgggagccccctgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcagcacagccgctccatgtcaatgcccgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgcccggcccgcacccgcccctgccgcatccgctgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcgggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagcccaggcgacctgcgcgccttctgcagtcaccgaagcaacacg cccgagtccatcgcggagacgcccccagcccgagacggcggcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgccgggtctcg ggggacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccaca ccggcccggcagcgaccggtgccccagccctcttctgcctcgctggatgagtacaccctg atgcgggccaccttctcgggcagcgcgggccgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagacatcgagatcggctcccac aggagctccagcagcaacctgggcgcagacgacggctacatgcccatgacgcccggcgcg gccctcgcgggcagtgggagcggtagctgcaggagcgacgactacatgcccatgagcccc gccagcgtgtccgcccccaagcagatcttgcaacctagggccgccgccgccgccaccgtg ccccctgcggggccagcgcccacctctgcggggggcaggacattcccggcgagcgggggt ggctacaaggccagctcgcccgccgagagctcccccgaggacagtgggtacatgcgcatg tggtgcggctccaagctgtccatggagcatgcagatggcaagctgctgcccaacggggac tacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgacttcttctcc gcagccctgcacgccggcggggagccgctcaggggcgttcccggctgctgctacagctcc ttgccccgctcctacaaggccccgtacacctgtggcgcggacagcgaccagtacgtgctc atgagctccccggtggggcgcatcctggaggaggagcggctggagcctcaggccacgcca ggggccggccccacgcagccccctcaccccgtagtgccttcgcccgtgcggcccagcggc ggcctaggcggcggccgcccggagggcttcttgggccagcgcggccgggcagtgcggccc acgcgcctgtccctggaggggctgcccagcctgcccagcatgcacgagtacccactgccg ccggagcccaagagccccggcgagtacatcaacatcgacttcggcgagtccggggcccgc ctgtcgccgcccgcgcctcccctgctggcgtcggcggcctcgtcctcctcgctcttgtcc gccagcagcccggcctcgtcgctgggctcaggcaccccaggcaccagcagcgacagccgg cagcgctctccgctctccgactacatgaacctcgacttcagctcccccaagtctcctaaa ccgggcgccccgagcggccatcccgtgggctccttggacggtctcctgtcccccgaggcc accccgtatccgccgctgcccccgcgtccgtccgcgtccccgtcgtcgtccctacagccg ccgccaccgccgccgcccccgggggagctgtaccgcctgccccccgcctcggccgctgcc actgcccagggcccgggcgccgcctcattgtcgtcctcggacaccggggacaatggtgac tacaccgagatggcttttggtgtggccgccaccccgccgcaacccatcgcggcccccccg aagccagaagcggcccgcgtggccagcccgacgtcgggcgtgaagaggctgagcctcatg gagcaggtgtcaggggtcgaggccttcctgcaggccagccagcccccggacccccaccgc ggcgccaaggtcatccgcgcagacccgcaggggggccgccgccgccacagttccgagacc ttctcctccaccacgacggtcacccccgtgtccccgtccttcgcccacaaccccaagcgc cacaactcggcctccgtagaaaatgtctctctcaggaaaagcagcgagggcggtgtgggt gtcggccctggagggggcgacgagccgcccacctcccctcgacagttgcagccggcgctc ccggcgccccctttggcaccgcagggccggccgtggaccccgggtcagcccgggggcttg atcggttgtcctgggagcggtggatcgccaatgcgcagggagacctctgccggcttccag aatggtctcaactacatcgccatcgacgtgagggaggagcccgggctgccaccccagccg cagccgcagccgccgccgccgcttcctcagccgggagacaagagctcctggggtcggacc cgaagcctcgggggtctcatcagcgctgtgggcgttggcagcaccggcggcgggtgcggg gggccgggtcccggtgccctgccacctgccaacacctacgccagcattgacttcttgtcc caccacttgaaggaggccaccatcgtgaaagagtga

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