KEGG   Symphalangus syndactylus (siamang): 129465288
Entry
129465288         CDS       T10134                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn01522  Endocrine resistance
ssyn04110  Cell cycle
ssyn04115  p53 signaling pathway
ssyn04151  PI3K-Akt signaling pathway
ssyn04218  Cellular senescence
ssyn04530  Tight junction
ssyn04660  T cell receptor signaling pathway
ssyn04933  AGE-RAGE signaling pathway in diabetic complications
ssyn04934  Cushing syndrome
ssyn05160  Hepatitis C
ssyn05162  Measles
ssyn05163  Human cytomegalovirus infection
ssyn05164  Influenza A
ssyn05165  Human papillomavirus infection
ssyn05166  Human T-cell leukemia virus 1 infection
ssyn05167  Kaposi sarcoma-associated herpesvirus infection
ssyn05169  Epstein-Barr virus infection
ssyn05200  Pathways in cancer
ssyn05203  Viral carcinogenesis
ssyn05212  Pancreatic cancer
ssyn05214  Glioma
ssyn05218  Melanoma
ssyn05219  Bladder cancer
ssyn05220  Chronic myeloid leukemia
ssyn05222  Small cell lung cancer
ssyn05223  Non-small cell lung cancer
ssyn05224  Breast cancer
ssyn05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    129465288 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    129465288 (CDK4)
   04115 p53 signaling pathway
    129465288 (CDK4)
   04218 Cellular senescence
    129465288 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    129465288 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    129465288 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129465288 (CDK4)
   05203 Viral carcinogenesis
    129465288 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    129465288 (CDK4)
   05225 Hepatocellular carcinoma
    129465288 (CDK4)
   05214 Glioma
    129465288 (CDK4)
   05220 Chronic myeloid leukemia
    129465288 (CDK4)
   05218 Melanoma
    129465288 (CDK4)
   05219 Bladder cancer
    129465288 (CDK4)
   05224 Breast cancer
    129465288 (CDK4)
   05222 Small cell lung cancer
    129465288 (CDK4)
   05223 Non-small cell lung cancer
    129465288 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129465288 (CDK4)
   05160 Hepatitis C
    129465288 (CDK4)
   05164 Influenza A
    129465288 (CDK4)
   05162 Measles
    129465288 (CDK4)
   05163 Human cytomegalovirus infection
    129465288 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129465288 (CDK4)
   05169 Epstein-Barr virus infection
    129465288 (CDK4)
   05165 Human papillomavirus infection
    129465288 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129465288 (CDK4)
   04934 Cushing syndrome
    129465288 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129465288 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssyn01001]
    129465288 (CDK4)
Enzymes [BR:ssyn01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     129465288 (CDK4)
Protein kinases [BR:ssyn01001]
 Serine/threonine kinases: CMGC group
  CDK family
   129465288 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 129465288
NCBI-ProteinID: XP_055103136
LinkDB
Position
17:32017492..32021679
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEELGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtcgctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgtgaggtggccttactg
aggcgactggaggcttttgagcatcccaatgttgtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaggaccta
aggacatatctggacaaggcgcccccaccaggcttgccagccgaaaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctagccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagcc
gaccagttgggcaaaatctttgacctgattgggctgcctccagaagatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagttgggagcacagctgctgctggaaatgctgacttttaacccg
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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