Symphalangus syndactylus (siamang): 129468352
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Entry
129468352 CDS
T10134
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn04022
cGMP-PKG signaling pathway
ssyn04024
cAMP signaling pathway
ssyn04062
Chemokine signaling pathway
ssyn04071
Sphingolipid signaling pathway
ssyn04270
Vascular smooth muscle contraction
ssyn04310
Wnt signaling pathway
ssyn04360
Axon guidance
ssyn04510
Focal adhesion
ssyn04520
Adherens junction
ssyn04530
Tight junction
ssyn04611
Platelet activation
ssyn04670
Leukocyte transendothelial migration
ssyn04810
Regulation of actin cytoskeleton
ssyn04921
Oxytocin signaling pathway
ssyn05132
Salmonella infection
ssyn05135
Yersinia infection
ssyn05163
Human cytomegalovirus infection
ssyn05200
Pathways in cancer
ssyn05205
Proteoglycans in cancer
ssyn05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
129468352 (ROCK2)
04071 Sphingolipid signaling pathway
129468352 (ROCK2)
04024 cAMP signaling pathway
129468352 (ROCK2)
04022 cGMP-PKG signaling pathway
129468352 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
129468352 (ROCK2)
04520 Adherens junction
129468352 (ROCK2)
04530 Tight junction
129468352 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129468352 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129468352 (ROCK2)
04670 Leukocyte transendothelial migration
129468352 (ROCK2)
04062 Chemokine signaling pathway
129468352 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
129468352 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
129468352 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
129468352 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129468352 (ROCK2)
05205 Proteoglycans in cancer
129468352 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
129468352 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
129468352 (ROCK2)
05135 Yersinia infection
129468352 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129468352 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssyn01001
]
129468352 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ssyn03036
]
129468352 (ROCK2)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
129468352 (ROCK2)
Protein kinases [BR:
ssyn01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
129468352 (ROCK2)
Chromosome and associated proteins [BR:
ssyn03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
129468352 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
129468352
NCBI-ProteinID:
XP_055109771
LinkDB
All DBs
Position
18:100983119..101151119
Genome browser
AA seq
1388 aa
AA seq
DB search
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
WDNIRETAAPVVPELSSDIDSSNFDDIEEDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEIQAKEELEQKCKSVNTRLEKT
AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRISGLEEDLKNGKI
LFAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
QLAPNKPS
NT seq
4167 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccgccgacggggaaaatgcccggcgcccccgagaccgcgccgggggac
ggggcaggcgcgagccgccagaggaagctggaggcgctgatccgagaccctcgctccccc
atcaacgtggagagcttgctggatggcttaaattccttggtccttgatttagattttcct
gctttgaggaaaaacaagaacatagataatttcttaaatagatatgagaaaattgtgaaa
aaaatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtgcagttggttcgtcataaggcatcgcagaaagtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatcagattctgcctttttttgggaagaa
agagatattatggcctttgccaatagcccctgggtggttcagcttttttatgcctttcaa
gatgataggtatctgtacatggtaatggagtacatgcctggtggagaccttgtaaacctt
atgagtaattatgacgtgcctgaaaaatgggccaaattttacactgctgaagttgttctt
gctctggatgcaatacactccatgggtttaatacacagagatgtgaagcctgacaacatg
ctcttggataaacatggacatctaaaattagcagattttggcacgtgtatgaagatggat
gaaacaggcatggtacattgtgatacagcagttggaacaccggattatatatcacctgag
gttctgaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgta
ggtgttttcctttatgagatgctagtgggggatactccattttatgcggattcacttgtg
ggaacatatagcaaaattatggatcataagaattcactgtgtttccctgaagatgcagaa
atttccaaacacgcaaagaatctcatctgtgctttcttaacagatagggaggtacgactt
gggagaaatggggtggaagaaatcagacagcatcctttctttaagaatgatcagtggcat
tgggataacataagagaaacggcagctcctgtagtacctgaactcagcagtgacatagac
agcagcaattttgatgacattgaagaagacaaaggagatgtagaaaccttcccaattcct
aaagcttttgttggaaatcagctgcctttcataggatttacctactatagagaaaattta
ttattaagtgactctccatcttgtagagaaaatgattcaatacaatcaaggaaaaatgaa
gaaagtcaagagattcagaaaaaactgtatacattagaagaacatcttagcaatgagata
caagccaaagaggaactggaacagaagtgcaaatctgttaatactcgcctagaaaaaaca
gcaaaggagctagaagaggagattaccttacggaaaagtgtggaatcagcattaagacag
ttagaaagagaaaaggcgcttcttcagcacaaaaatgcagaatatcagaggaaagctgat
catgaagcagataaaaaacgaaatttggaaaatgatgttaacagcttaaaagatcaactt
gaagatttgaaaaaaagaaatcaaaactctcaaatatccactgagaaagtgaatcaactc
cagagacaactagatgaaaccaatgctttactgcgaacagaatctgatactgcagcccga
ttaaggaaaacccaggcagaaagttcaaaacagattcagcagctggaatctaacaataga
gatctacaagataaaaactgcctgctggagactgccaagttaaaacttgaaaaggaattt
atcaatcttcagtcagctctagaatctgaaaggagggatcgaactcatggatcagagata
attaatgatttacaaggtagaatatctggcctagaagaagatttaaagaacggcaaaatc
ttatttgcgaaagtagaactggagaagagacaactacaggagagatttactgatttggaa
aaggaaaaaagcaacatggaaatagatatgacataccaactaaaagttatacagcagagc
ctagaacaagaagaagctgaacataaggccacaaaggcacgactagcagataagaataag
atctatgagtccatcgaagaagccaaatcagaagccatgaaagaaatggagaagaagctc
ttggaggaaagaactttaaaacagaaagtggagaacttattgctagaagctgagaaaaga
tgttctctattagactgtgacctcaaacagtcacagcagaaaataaatgagctccttaaa
cagaaagatgtgctaaatgaggatgttagaaacctgacgttaaaaatagagcaagaaact
cagaagcgctgccttacacaaaatgacctgaagatgcaaacacaacaggttaacacacta
aaaatgtcagaaaagcagttaaagcaagaaaataaccatctcatggaaatgaaaatgaac
ttggaaaaacaaaatgctgaacttcgaaaagaacgtcaggatgcagatgggcaaatgaaa
gagctccaggatcagctcgaagcagaacagtatttctcaaccctttataaaacacaagtt
agggagcttaaagaagaatgtgaagaaaagaccaaacttggtaaagaattgcagcagaag
aaacaggaattacaggatgaacgggactccttggctgcccaactggagatcaccttgacc
aaagcagattctgagcaactggctcgttcaattgccgaagaacaatattctgatttggaa
aaagagaagatcatgaaagagctagagatcaaagagatgatggctagacacaaacaggaa
cttactgaaaaagatgctacaattgcttctcttgaagaaactaataggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaattgaaagatgttcaa
gagcaactgtcaagattgaaagatgaagaaataagcgcagcagctattaaagcacagttt
gagaaacagctattaacagaaagaacactcaaaactcaagctgtgaataagttggctgag
atcatgaatcgaaaagaacctgtcaagcgtggtaatgacacagatgtgcggagaaaagag
aaggagaatagaaagctacatatggagcttaaatctgaacgtgagaaattgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggcacaaatagctgaagagagccag
attcgaattgaactgcagatgacattggacagtaaagacagtgacattgagcagctgcgg
tcacaactccaagccttgcatattggtctggatagttccagtataggcagtggaccaggg
gatgctgaggcagatgatgggtttccagaatcaagattagaaggatggctttcattgcct
gtacgaaacaacactaagaaatttggatgggttaaaaagtatgtgattgtaagcagtaag
aagattcttttctatgacagtgaacaggataaagaacaatccaatccttacatggtttta
gatatagacaagttatttcatgtccgaccagttacacagacagatgtatatagagcagat
gctaaagaaattccaaggatattccagattctgtatgccaatgaaggagaaagtaagaag
gaacaagaatttccagtggagccagttggagaaaaatctaattatatttgccacaaggga
catgagtttattcctactctttatcatttcccaaccaactgtgaggcttgtatgaagccc
ctgtggcacatgtttaagcctcctcctgctttggagtgccgccgttgccatattaagtgt
cataaagatcacatggacaaaaaggaggagattatagcaccttgcaaagtatattatgat
atttcaacggcaaagaatctgttattactagcaaattctacagaagagcagcagaagtgg
gttagtcggttggtgaaaaagatacctaaaaagcccccagctccagacccttttgcacga
tcatctcctagaacttcaatgaagatacagcaaaaccagtctattagacggccaagtcga
cagcttgccccaaacaaacctagctaa
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