KEGG   Symphalangus syndactylus (siamang): 129484345
Entry
129484345         CDS       T10134                                 
Symbol
TPH1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn00380  Tryptophan metabolism
ssyn00790  Folate biosynthesis
ssyn01100  Metabolic pathways
ssyn04726  Serotonergic synapse
Module
ssyn_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    129484345 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    129484345 (TPH1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    129484345 (TPH1)
Enzymes [BR:ssyn01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     129484345 (TPH1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT ACT_4 zf-C2HE
Other DBs
NCBI-GeneID: 129484345
NCBI-ProteinID: XP_055138184
LinkDB
Position
6:38117594..38144582
AA seq 444 aa
MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTVKEDGMETVPWFPKKISDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA
MNELQHDLDVVSDALAKVSRKPSI
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgattgaagacaataaggagaacaaagaccattccttagaaaggggaagagcaagtctc
attttttccttaaagaatgaagttggaggacttataaaagccttgaaaatttttcaggag
aagcatgtgaatctgttacatatcgaatcccgaaaatcaaaaagaagaaactcagaattt
gagatttttgttgactgtgacatcaacagagaacaactgaatgatatttttcatctgctg
aagtctcataccaatgttctctctgtgaatccaccagataattttactgtgaaggaagat
ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccattgtgccaac
agagttctgatgtatggatctgaactagatgcagaccatcctggcttcaaagacaatgtc
taccgcaaacgtcgaaagtattttgcggacttggctatgaactataaacatggagacccc
attccaaaggttgaattcactgaagaggagattaagacctggggaaccgtattccaagag
ctcaacaaactctacccaacccatgcttgcagagagtatctcaaaaacttacctttgctt
tctaaatattgtggatatcgggaagataatatcccacaattggaagatgtctccaacttt
ttaaaagagcgtacaggtttttccatccgtcctgtggctggttacttatcaccaagagat
ttcttatcaggtttagcctttcgagtttttcattgcactcaatatgtgagacacagttca
gatcccttctataccccagagccagatacctgccatgaactcttaggccatgtccctctt
ttggctgaacctagttttgcccaattctcccaagaaattggcttggcttctcttggcgct
tcagaggaggctgttcaaaaactggcaacgtgctactttttcactgtggagtttggtcta
tgtaaacaagatggacagctaagagtctttggtgctggcttactttcttctatcagtgaa
ctcaaacatgcactttctggacatgccaaagtaaagccctttgatcccaagattacctgc
aaacaggaatgtcttatcacaacttttcaggatgtctactttgtatctgaaagttttgaa
gatgcaaaggagaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag
tataatccatatacacggagtattcagatcctgaaagacaccaagagcataaccagtgcc
atgaacgagttgcagcatgatcttgatgttgtcagtgatgcccttgctaaggtcagcagg
aagccaagtatctaa

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